Increased intrapharyngeal pressure with combined use of high-flow nasal cannula and a surgical face mask: a preliminary study

OBJECTIVES: Nasal high-flow (NHF) therapy provides continuous positive airway pressure (CPAP), flushes the anatomical dead space, and improves mucociliary clearance. CPAP is usually applied at a flow rate at or above an established threshold value with the mouth closed because it is hard to maintain it with an open mouth. We conducted a prospective study to validate our hypothesis that CPAP can be applied with the mouth open through a surgical face mask. METHODS: We inserted 12-Fr nasogastric tubes through the noses of 18 healthy individuals and fixed each tube within the pharynx to monitor the intrapharyngeal pressure. We monitored the pressure during the following two conditions: NHF oxygen with the mouth open (condition O) and NHF oxygen with the mouth open and wearing a surgical face mask (condition OM). We set the NHF rate at 40 L/min and the oxygen concentration at 21%, under all conditions. We measured the intrapharyngeal pressure five times during each inspiration and expiration, and calculated mean values. RESULTS: The mean expiratory intrapharyngeal pressure (median [interquartile range]) increased significantly from the baseline during conditions O (2.08 [1.58–4.02] cm H(2)O) and OM (3.35 [2.72–3.79] cm H(2)O). In addition, there was a significant difference in pressure between conditions O and OM (p=0.0263, Wilcoxon signed-rank test). CONCLUSIONS: In our healthy volunteers, the intrapharyngeal pressures increased during expiration with an open mouth while wearing a surgical face mask

Momentum reconstruction of charged particles using multiple Coulomb scatterings in a nuclear emulsion detector

This paper describes a new method for momentum reconstruction of charged particles using multiple Coulomb scatterings (MCS) in a nuclear emulsion detector with a layered structure of nuclear emulsion films and target materials. The method utilizes the scattering angles of particles precisely measured in the emulsion films. The method is based on the maximum likelihood to newly include information on the decrease of the energy as the particle travels through the detector. According to the MC simulations, this method can measure momentum with a resolution of 10% for muons of 500 MeV/c passing through the detector perpendicularly. The momentum resolution is evaluated to be 10-20%, depending on the momentum and emission angle of the particle. By accounting for the effect of the energy decrease, the momentum can be reconstructed correctly with less bias, particularly in the low-momentum region. We apply this method to measure the momentum of muon tracks detected in the NINJA experiment where the momentum is also measured independently by using the track range. The two measurements agree well within experimental uncertainties of a 2% difference, verifying the method experimentally. This method will extend the measurable phase space of muons and hadrons in the NINJA experiment.Comment: 19 pages, 14 figure

Early Spectroscopy of the 2010 Outburst of U Scorpii

We present early spectroscopy of the recurrent nova U~Sco during the outburst in 2010. We successfully obtained time-series spectra at $t_{\rm d}=$0.37--0.44~d, where $t_{\rm d}$ denotes the time from the discovery of the present outburst. This is the first time-resolved spectroscopy on the first night of U Sco outbursts. At $t_{\rm d}\sim 0.4$~d the H$\alpha$ line consists of a blue-shifted ($-5000$ km s$^{-1}$) narrow absorption component and a wide emission component having triple peaks, a blue ($\sim -3000$ km s$^{-1}$), a central ($\sim 0$ km s$^{-1}$) and a red ($\sim +3000$ km s$^{-1}$) ones. The blue and red peaks developed more rapidly than the central one during the first night. This rapid variation would be caused by the growth of aspherical wind produced during the earliest stage of the outburst. At $t_{\rm d}=1.4$~d the H$\alpha$ line has a nearly flat-topped profile with weak blue and red peaks at $\sim \pm 3000$ km s$^{-1}$. This profile can be attributed to a nearly spherical shell, while the asphericity growing on the first night still remains. The wind asphericity is less significant after $t_{\rm d}=9$ d.Comment: 5 pages, 3 figures, Accepted for publication of PASJ Letter

Case Analysis on the Diversity of Business Action

経済のグローバル化の進展,情報通信技術(IT)の飛躍的発展,種々の規制緩和の実施,環境保全意識の高揚,少子・高齢化の急速な進行など,日本企業をめぐる経済的・社会的環境が大きく変化している今日,環境適応のための企業の経営行動は多様化してきている.この論文は,このような変革期の時代に企業の経営行動がどのような方向性をもち,どのような変化を追求しているのかについて,2つのケース分析を通じて検討を行っている.第1のケースは,日本における新しいタイプの社会福祉事業を実践する「ヤマト福祉財団」を取り上げ,非営利組織の経営革新の実態を分析している.第2のケースは,「ソニー」を取り上げ,出井伸之氏がトップマネジメントとして牽引した10年間の経営行動の成否を分析している.The economical social environment around the Japanese enterprises, such as the globalization of the economy, the rapid development of information technology, the various deregulations, the increasing awareness of environmental preservation, and the coming of the society with the falling birthrates and the aging population, changes rapidly. The business action of Japanese enterprises is diversified for the adaptation to this environmental change. We examine what kind of directionality the business action has and what kind of change the enterprises pursue in the reform period through two case analyses. The first case takes up "Yamato Welfare Foundation", and analyzes the reality of management innovation of a nonprofit organization. The second case takes up "Sony", and analyzes the success or failure factors of the business action throughout the period Mr. Nobuyuki Idei has assumed Chief Operating Officer and Chief Executive Officer

4/3-Law of Granular Particles Flowing through a Vertical Pipe

Density waves of granular material (sand) flowing through a vertical pipe have been investigated. Clear density waves emerge when the cock attached to bottom end of the pipe is closed. The FFT power spectra were found to show a stable power-law form $P(f) \sim f^{-\alpha}.$ The value of the exponent was evaluated as $\alpha \cong 4/3$. We also introduce a simple one-dimensional model which reproduces $\alpha = 4/3$ from both simulation and theoretical analysis. (to be published in Phys.Rev.Lett.)Comment: 4 pages, 4 figures, a style fil

Study on development policy for new cryogenic structural material for superconducting magnet of fusion reactor

A fusion DEMO will require large-scale cryogenic structure including TF coil cases. Because of huge electromagnetic forces, extra thick plates and/or wrought products will be supplied. Since the midsection of the huge block is weaker than the block surface region, the design yield stress must be determined taking account of this lower strength part. To search the manufacturing process to improve the midsection strength, the crystal refinement strengthening and the precipitation strengthening are considered together with the carbon and nitrogen solid solution strengthening. XM-19 was focused based on the variation of the yield stress and the fracture toughness, a 100 mm thick block and a 30 mm thick plate were trial produced, and strength and the fracture toughness at the midsection were evaluated. This study will present the experimental data and discuss the development policy for a new cryogenic structural material for a fusion reactor