446 research outputs found

    Antecedents and Consequences of Global Supply Chain Process Integration

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    Global business executives and researchers recently highlight the importance of understanding the dynamics of supply chain process integration in a global context. The literature still lacks studies that provide a comprehensive understanding of the major antecedents and consequences of supply chain process integration from a global perspective. This dissertation builds on several theoretical foundations such as the resource based view (RBV), the relational view (RV) of the firm and transaction cost analysis (TCA) to develop a framework that explains the drivers and outcomes of global supply chain process integration. This global study responds to these challenges through exploring the antecedents and consequences of global supply chain process integration for 320 supply chain and purchasing managers that source from over 33 countries. A theoretical framework is proposed that builds on research in strategic management, supply chain management, and international business and tests 8 proposed hypotheses. One new construct – global supply chain process integration – is developed and tested. Another construct, logistics performance, is modified from its existing form in the current literature. Significant results and good fit indices tested with structural equation modeling generate a number of interesting implications for global supply chain managers and researchers. For executives and strategists who are concerned about better managing their supply chains, this study provides insights for how manufacturing firms can develop a competitive edge through a higher level of flexibility by integrating its supply chain processes with its global suppliers. The study also provides empirical evidence on how supplier flexibility in a global environment can lead to improvements in process and firm performance

    Kernel-Based Estimation of P(X less than Y)With Paired Data

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    A point estimation of P(X \u3c Y) was considered. A nonparametric estimator for P(X \u3c Y) was developed using the kernel density estimator of the joint distribution of X and Y, may be dependent. The resulting estimator was found to be similar to the estimator based on the sign statistic, however it assigns smooth continuous scores to each pair of the observations rather than the zero or one scores of the sign statistic. The asymptotic equivalence of the sign statistic and the proposed estimator is shown and a simulation study is conducted to investigate the performance of the proposed estimator. Results indicate that the estimator has a good overall performance

    Solving Modal Equations of Motion with Initial Conditions Using MSC/NASTRAN DMAP

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    By utilizing MSC/NASTRAN DMAP (Direct Matrix Abstraction Program) in an existing NASA Lewis Research Center coupled loads methodology, solving modal equations of motion with initial conditions is possible using either coupled (Newmark-Beta) or uncoupled (exact mode superposition) integration available within module TRD1. Both the coupled and newly developed exact mode superposition methods have been used to perform transient analyses of various space systems. However, experience has shown that in most cases, significant time savings are realized when the equations of motion are integrated using the uncoupled solver instead of the coupled solver. Through the results of a real-world engineering analysis, advantages of using the exact mode superposition methodology are illustrated

    Solving modal equations of motion with initial conditions using MSC/NASTRAN DMAP. Part 1: Implementing exact mode superposition

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    Within the MSC/NASTRAN DMAP (Direct Matrix Abstraction Program) module TRD1, solving physical (coupled) or modal (uncoupled) transient equations of motion is performed using the Newmark-Beta or mode superposition algorithms, respectively. For equations of motion with initial conditions, only the Newmark-Beta integration routine has been available in MSC/NASTRAN solution sequences for solving physical systems and in custom DMAP sequences or alters for solving modal systems. In some cases, one difficulty with using the Newmark-Beta method is that the process of selecting suitable integration time steps for obtaining acceptable results is lengthy. In addition, when very small step sizes are required, a large amount of time can be spent integrating the equations of motion. For certain aerospace applications, a significant time savings can be realized when the equations of motion are solved using an exact integration routine instead of the Newmark-Beta numerical algorithm. In order to solve modal equations of motion with initial conditions and take advantage of efficiencies gained when using uncoupled solution algorithms (like that within TRD1), an exact mode superposition method using MSC/NASTRAN DMAP has been developed and successfully implemented as an enhancement to an existing coupled loads methodology at the NASA Lewis Research Center

    Citric acid strongly inhibits visceral pain response in mice

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    Citric acid introduced into the stomach of mice at increasing concentrations of 0.1, 1 or 10 % (4.8 µM-0.48 mM; 95 µmol/kg-9.5 mmol/kg, 0.5 ml) caused dose-dependent inhibition of abdominal constrictions induced 1 h later by i. p. acetic acid injection by -51 % to -69.5 %. When administered at 10 % (0.48 mM, 0.5 ml) 15 min before nociceptive challenge, citric acid inhibited the nociceptive response by 96.8 %. Inhibition of the acetic acid-induced abdominal constrictions was also observed when lower doses of citric acid were introduced into the stomach (0.2 ml of 0.1-1 %; 38.1 µmol/kg-0.38 mmol/kg). The effect was evident as early as 5 min after administration of citric acid into the stomach and with the maximal effect being at 15-30 min after dosing. Lidocaine given orally 5 min prior to citric acid (1 %, 48 µM; 0.38 mmol/kg, 0.2 ml) prevented antinociception by citric acid, but lidocaine given 15 min before oral introduction of citric acid enhanced the citric acid-induced inhibition of the nociceptive response to acetic acid. The antinociceptive effect of orally administered citric acid (1 %, 48 µM; 0.38 mmol/kg, 0.2 ml) was increased by pre-treatment with propranolol (4 mg/kg, s. c.), yohimbine (4 mg/kg, s. c.), guanethidine (32 mg/kg, s. c.), but reduced after treatment with atropine (3 mg/kg, s. c.), which itself increased the nociceptive behavior. Similar inhibition of the acetic acid-induced nociceptive behavior was also observed when sodium citrate (pH 7.21) or 0.1 N HCl (pH 3) or 1 % sucrose solution (0.2 ml) was intragastrically given. It is suggested that citric acid might act to stimulate sensory afferents and that transmission of nociceptive information centrally leads to the activation of descending antinociceptive mechanism to a noxious stimulus

    West Texas Intermediate and Brent Spread during Organization of the Petroleum Exporting Countries Supply Disruptions

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    This paper investigates the price spread between West Texas Intermediate and Brent during periods of supply disruptions. Using a sample of 50 events of Organization of the Petroleum Exporting Countries (OPEC) - related unplanned upstream production outages, this paper documents a statistically significant tightening in the price differential. The finding is robust even after accounting for 22 OPEC - related political conflicts, 104 extreme weather conditions in the Atlantic basin, and the period of infrastructural bottlenecks in and around the Cushing, Oklahoma. The result is further confirmed when examining the spread between Light Louisiana sweet and Brent. These findings suggest the need to hedge against such risks and give rise to speculative trading which can be facilitated using the vibrant paper markets. Keywords: Crude Oil, Benchmarks, Organization of the Petroleum Exporting Countries, Supply Disruptions JEL Classifications: G12, Q34, Q4

    Response of Polycrystalline Solar Cell Outputs to Visible Spectrum and other Light Sources-a Case Study

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    In this case study, two polycrystalline solar modules were installed outdoors (irradiated by sunlight) and indoors (irradiated by artificial lights). The solar cells in both cases were installed using different color filters that allowed the passage of certain light frequencies. The amount of energy produced by each module were measured and compared to a reference module with no filter. The results indicated the variable response of polycrystalline solar cells to natural and artificial light sources, being more responsive in both cases to red band color as could be deduced from their % current outputs (72.5% sunlight radiation; 84.38% artificial light sources). Other colors, including yellow, green, orange and violet afforded acceptable outputs. The results indicated that electrical outputs of indoor solar cells decreased when colored filters were used, but red filter in general afforded the maximum outputs, for both the artificially radiated indoor and naturally radiated outdoor solar cells. The case study suggests the possible complementary advantage of using indoor mounted solar cells for the production of electricity during artificial illumination period of the day
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