Laparoscopic Removal of an Incidental Ectopic Liver: Short Report of a Case

Ectopic liver is a rare clinical entity, which may be rarely of clinical importance. It is generally reported to be small in size and without a connection to the mother liver. A case of an incidental ectopic liver nodule that was connected with a vascular peduncle to the Couinad segment IVa of the liver has been reported. Microscopic examination revealed chronic inflammatory changes, which should be considered to be the result of intermittent circulatory disturbances

Medicolegal Approach to Child Physical Abuse in an Emergency Clinic

Child abuse is a global health problem. For this reason, it is important to perform suitable medical approaches in suspected cases of child abuse in the emergency room. The first consideration is performing life-saving medical approaches. Reporting the case to judicial authorities and the correlation of medical examination findings with medicolegal history are other important steps. We report a case of a 3-year-old male child who died after severe physical abuse. In suspected cases of child abuse, examination of the fundus is important. If death occurs, histopathological examination of eye globes must be performed to determine the cause of death. The present case was the first in which eye globe examination was performed in Izmir, Turkey. Autopsy findings revealed subdural hemorrhage and subarachnoid hemorrhage caused by blunt trauma. The cause of death was blunt head trauma, and the manner of death was listed as homicide. Except for microhemorrhages in the optic nerve sheath, no pathological finding was identified in the retina. Retinal hemorrhage can be seen in child abuse cases, and it is associated with a poor prognosis if present; however, the absence of retinal hemorrhage does not exclude child abuse. Crime scene investigation findings, witnesses' statements, medical records, and autopsy findings must all be taken into consideration in child abuse cases in a correlative and holistic manner

Medicolegal Approach to Child Physical Abuse in an Emergency Clinic

Child abuse is a global health problem. For this reason, it is important to perform suitable medical approaches in suspected cases of child abuse in the emergency room. The first consideration is performing life-saving medical approaches. Reporting the case to judicial authorities and the correlation of medical examination findings with medicolegal history are other important steps. We report a case of a 3-year-old male child who died after severe physical abuse. In suspected cases of child abuse, examination of the fundus is important. If death occurs, histopathological examination of eye globes must be performed to determine the cause of death. The present case was the first in which eye globe examination was performed in Izmir, Turkey. Autopsy findings revealed subdural hemorrhage and subarachnoid hemorrhage caused by blunt trauma. The cause of death was blunt head trauma, and the manner of death was listed as homicide. Except for microhemorrhages in the optic nerve sheath, no pathological finding was identified in the retina. Retinal hemorrhage can be seen in child abuse cases, and it is associated with a poor prognosis if present; however, the absence of retinal hemorrhage does not exclude child abuse. Crime scene investigation findings, witnesses' statements, medical records, and autopsy findings must all be taken into consideration in child abuse cases in a correlative and holistic manner

Silymarin attenuates the renal ischemia/reperfusion injury-induced morphological changes in the rat kidney

Objectives Renal ischemia/reperfusion (I/R) injury is associated with increased mortality and morbidity rates due to acute renal failure (ARF). Oxidative stress induced with renal I/R injury directly affects glomerular and tubular epithelium through reactive oxygen species. Several studies have been directed to the treatment of renal I/R injury. The aim of this study was to test the attenuation with silymarin (SM) treatment of renal I/R injury-induced morphological changes in the rat kidney

Protective effects of vitamin E on central nervous system in streptozotocin-induced diabetic rats

Objective: To evaluate the histopathological and antioxidant effects of vitamin E (VE) treatment on brain tissue in streptozotocin (STZ)-induced diabetic rats. Methods: Thirty two male Wistar albino rats were used. The study comprised four groups of 8 rats: Group A - untreated group, group B - diabetic group, group C - VE and group D - diabetic plus VE. In the diabetic groups, diabetes was induced by a single intraperitoneal injection of 65 mg/kg STZ. Vitamin E was given 50 mg/kg/day i.p. for three weeks. Concentrations of glucose, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were detected in the haemolysate. Results: Glucose concentrations were increased in the blood of the STZ-treated rats compared with those in the diabetic groups (group B and D). The MDA concentrations in the brain from diabetic rats increased, whereas the GPx, SOD, CAT concentrations decreased. Treatment with VE returned concentrations of MDA, GPx, SOD and CAT toward control values. The MDA concentration in the diabetic group (20.65±2.24 nmol/mg Hb) was decreased compared with the VE treated group (15.54±1.32 nmol/mg Hb). There were no pathological differences between untreated and VE treated rats’ brains. Neuronal ischemic damages were determined in STZ-induced diabetic rats. Ischemic neuronal alterations in group B (diabetic) had more damage than group D (diabetic + VE). Conclusion: The study revealed neuroprotective effects of VE on ischemic damage in diabetic central neuronal cells, caused by diabetic oxidative stress