19 research outputs found
Effectiveness of septoplasty versus non-surgical management for nasal obstruction due to a deviated nasal septum in adults: study protocol for a randomized controlled trial
Intranasal ketamine for anesthetic premedication in children: a systematic review.
Aim
In children, intravenous anesthetic premedication can be distressing. Intranasal (IN) ketamine offers a less invasive approach.
Materials and Methods
We included randomized trials of IN ketamine in anesthetic premedication in children 0-19 years. We performed electronic searches of MEDLINE, EMBASE, Google Scholar, CINAHL, Cochrane Library, Web of Science, Scopus, clinical trial registries and conference proceedings.
Results
Among the 23 trials (n = 1680) included, IN ketamine adequately sedated 220/311 (70%) for face mask application, 217/308 (70%) for caregiver separation, 200/371 (54%) for iv. insertion and 19/30 (63%) for monitor application. Vomiting was the most common adverse effect (35/1579 [2.2%]).
Conclusion
There is a need for sufficiently powered, methodologically rigorous trials, using psychometrically evaluated, objective outcome measures to meaningfully inform practice
Sirtuin-1 Controls Poly (I:C)–Dependent Matrix Metalloproteinase 9 Activation in Primary Human Nasal Epithelial Cells
Endoscopic-assisted septoplasty versus traditional septoplasty: assessment by the NOSE scale
Myeloperoxydase Expression in The Pathogenesis of Nasal Polyps
Nasal polyps are benign mucosal protrusions that expand into the nasal cavity. There are no any etiological factors that may explain the pathogenesis of nasal polyps but currently inflammation continues to be the major factor. As a result of inflammation, neutrophils become activated and migrate to the inflammatory area and form their bactericidal effects by producing free oxygen radicals. The objective of our study is to investigate the expression of myeloperoxydase enzyme, which is usually an indicator of leukocyte infiltration and is responsible in the formation of free oxygen radicals in polyp tissues and to determine its role in the pathogenesis of nasal polyps