On 'Light' Fermions and Proton Stability in 'Big Divisor' D3/D7 Swiss Cheese Phenomenology

Building up on our earlier work [1,2], we show the possibility of generating "light" fermion mass scales of MeV-GeV range (possibly related to first two generations of quarks/leptons) as well as eV (possibly related to first two generations of neutrinos) in type IIB string theory compactified on Swiss-Cheese orientifolds in the presence of a mobile space-time filling D3-$brane restricted to (in principle) stacks of fluxed D7-branes wrapping the "big" divisor \Sigma_B. This part of the paper is an expanded version of the latter half of section 3 of a published short invited review [3] written up by one of the authors [AM]. Further, we also show that there are no SUSY GUT-type dimension-five operators corresponding to proton decay, as well as estimate the proton lifetime from a SUSY GUT-type four-fermion dimension-six operator to be 10^{61} years. Based on GLSM calculations in [1] for obtaining the geometric Kaehler potential for the "big divisor", using further the Donaldson's algorithm, we also briefly discuss in the first of the two appendices, obtaining a metric for the Swiss-Cheese Calabi-Yau used, that becomes Ricci flat in the large volume limit.Comment: v2: 1+25 pages, Title modified and text thoroughly expanded including a brief discussion on obtaining Ricci-flat Swiss Cheese Calabi-Yau metrics using the Donaldson's algorithm, references added, to appear in EPJ

A self-optimised approach to synthesising DEHiBA for advanced nuclear reprocessing, exploiting the power of machine-learning

In an effort to advance the development of hydrometallurgical reprocessing of used nuclear fuel across the globe, this work sets out to explore and identify an optimised, cost effective pathway to synthesise the ligand DEHiBA (N,N-di-(2-ethylhexyl)isobutyramide). Currently, very few chemical suppliers stock and distribute this specialist ligand, designed for selective uranium chelation and extraction from nuclear fuel. The current high cost of DEHiBA therefore restricts access to essential large-scale testing of this promising ligand designed to advance nuclear reprocessing. This work utilises an automated flow reactor platform for the efficient optimisation of four synthetic routes to DEHiBA. These optimisations focus on optimising cost, reagent efficiency, yield, and productivity target functions by exploiting the power of machine-learning algorithms for rapid process development. Ultimately, we have identified an efficient and cost-effective solvent-free route to DEHiBA from isobutyric anhydride and di-2-ethylhexylamine for 99%, at a purity of 76%, and a process mass intensity of 1.29 g g−1, whilst alternative conditions demonstrated productivities >75 kg L−1 h−1, all whilst maintaining a high level of process control with outlet temperatures not exceeding 35 °C

Duality Twists, Orbifolds, and Fluxes

We investigate compactifications with duality twists and their relation to orbifolds and compactifications with fluxes. Inequivalent compactifications are classified by conjugacy classes of the U-duality group and result in gauged supergravities in lower dimensions with nontrivial Scherk-Schwarz potentials on the moduli space. For certain twists, this mechanism is equivalent to introducing internal fluxes but is more general and can be used to stabilize some of the moduli. We show that the potential has stable minima with zero energy precisely at the fixed points of the twist group. In string theory, when the twist belongs to the T-duality group, the theory at the minimum has an exact CFT description as an orbifold. We also discuss more general twists by nonperturbative U-duality transformations.Comment: 30 pages, harvmac, references and brief comments on gauged supergravity adde

Status of cassava begomoviruses and their new natural hosts in Nigeria

A diagnostic survey was conducted in 2002-03 to determine the status of cassava mosaic begomoviruses in Nigeria and to ascertain if the virulent Ugandan variant of East African cassava mosaic virus (EACMV-Ug2) was present. Of the 418 farms visited, 48% had cassava with moderately severe or severe symptoms, whereas 52% had cassava with mild symptoms. These distributions were at random. Of the 1,397 cassava leaf samples examined, 1,106 had symptoms. In polymerase chain reaction tests, 74.1% of the symptom-bearing samples tested positive for African cassava mosaic virus (ACMV) alone, 0.3% for EACMV alone, 24.4% for mixed infections by the two viruses, and 1.2% did not react with any of the primers used. The two viruses also were detected in 32% of the 291 symptomless plants and in the whitefly vector samples. EACMV-Ug2, Indian cassava mosaic virus, and South African cassava mosaic virus were not detected in any of the whitefly or leaf samples. Most farms had ACMV in single infection as well as in mixed infections with EACMV. Most doubly infected plants showed severe symptoms. Two biological variants of ACMV were identified based on symptom expression on cassava in the field. ACMV and EACMV were detected in the leguminous plant Senna occidentalis (L.) Link and the weed Combretum confertum Lams.; these are new natural hosts of the viruses. Although the virulent EACMV-Ug2 was not detected, the occurrence of variants of ACMV and a high proportion of mixed infections by ACMV and EACMV, which could result in recombination events such as the one that produced EACMV-Ug2, demands appropriate measures to safeguard cassava production in Nigeria

The occurrence of African cassava mosaic virus and East African cassava mosaic Cameroon virus in natural hosts other than cassava in Nigeria

Cassava mosaic disease (CMD) in Africa is caused by six distinct cassava mosaic viruses (family eminiviridae, genus Begomovirus). Among them, African cassava mosaic virus (ACMV) and East African cassava mosaicCameroon virus (EACMCV) have been reported in CMD-infected cassava plants in Nigeria. Based on PCR tests using virus-specific primers, a leguminous plant Senna occidentalis and the weed Combreturn confertumwere previously identified as natural hosts for ACMV and EACMCV and castor oil plant Ricinus cornmunis as a host for ACMV. In a recent study, we identified a second leguminous plant Leucana leucocephala as a host for ACMV and EACMCV. In order to confirm the PCR results, we have amplified 1 kbp DNA fragments specific to ACI and AV2 open reading frames (OW) of ACMV and AC3 and ACI ORFs of EACMCV. The amplicons were cloned and nucleotide sequences compared with corresponding sequences of ACMV and EACMCV isolates from cassava. All ACMV isolates from the four natural hosts showed sequence identity between 95 and 96 percent with cassava isolates. Similarly, all EACMCV isolates from the three natural hosts showed nucleotide sequence identity above 98 percent with isolates from cassava. The results confirm the natural occurrence of ACMV and EACMCV in four plant species other than cassava and indicate that theymay play a role in the epidemiology of CMD in Nigeria

Alternate hosts of African cassava mosaic virus and East African cassava mosaic Cameroon virus in Nigeria

Published online: 26 July 2008Cassava mosaic disease (CMD) caused by African cassava mosaic virus (ACMV) and East African cassava mosaic Cameroon virus (EACMCV) is the major constraint to cassava production in Nigeria. Sequences of the DNA-A component of ACMV and EACMCV isolates from leguminous plant species (Senna occidentalis, Leucana leucocephala and Glycine max), castor oil plant (Ricinus communis), a weed host (Combretum confertum) and a wild species of cassava (Manihot glaziovii) were determined. All ACMV isolates from these hosts showed 96–98% nucleotide sequence identity with cassava isolates from West Africa. EACMCV was found only in four hosts (S. occidentalis, L. leucocephala, C. confertum, M. glaziovii), and sequences of these isolates showed 96–99% identity with cassava isolates from West Africa. These results provide definitive evidence for the natural occurrence of ACMV and EACMCV in plant species besides cassava