Phytochemical, Proximate Analysis and Mineral Composition of Aqueous Crude Extract of Ficus Asperifolia Miq.

To determine the chemical constituents, proximate, phytochemical analysis and mineral composition of the crude aqueous extract of the leaves of Ficus asperifolia. The extracts were subjected to proximate and phytochemical screening. The mineral contents were determined using standard biochemical methods and equipment. Phytochemical studies carried out on aqueous extract of Ficus asperifolia leaves showed the presence of alkaloid, saponin, phenol, tannin, cardiac glycoside, steroid, cardenolides and phlobatannins while terpenes, flavonoids, anthraquinones and chalcones were not detected. Analyses showed that the sample has high level of Carbohydrate (42.64%), moderate amount of Crude Fibre and Protein (18.41 and 14.73%), respectively and little amount of Ash content (9.78%) and Crude Fat (3.16%). Also a considerable level (11.29%) of moisture was shown. This composition shows that the sample could be a good source of Carbohydrate, Dietary Fibre and Protein. Sodium and Potassium content (0.185±0.002 and 0.367±0.007%), respectively indicates the tendency of Ficus asperifolia to be able to regulate or control the osmotic balance of the body fluid as well as body pH. Ficus asperifolia is also found to be rich in Phosphorus (0.349±0.002%) and Calcium (0.203±0.002%), which is essential for bone formation. Magnesium, (0.428±0.003%) is also present, which could help to lower the blood pressure. Antioxidant minerals Zinc (64.45±0.15 mg/kg), Iron (7.00±0.20 mg/kg), Copper (13.35±0.15 mg/kg) and Selenium (0.0027±0.01 mg/kg) are also present. Our findings therefore, suggest that there is an indication that Ficus asperifolia contains important phytochemicals, proximate and mineral compounds that may be linked to its beneficial effects on health

Persistence of Rhizobium inoculants originating from Leucaena leucocephala fallowed plots in Southwest Nigeria

Ten core soil samples were collected from experimental plots at IITA, SW Nigeria that were previously inoculated with Rhizobium strains (IRC1045 and IRC 1050) specific for Leucaena leucocephala at two depths; 0—15 cm and 15—30 cm. The control soil samples were collected at similar depths from an adjacent field with no previous history of legume cultivation. Six weeks after planting of L. leucocephala in the soil samples in the greenhouse shoots, roots and nodules were harvested aseptically. Typing of the nodules as well as the identification of the persisting population of the introduced strains were based on the intrinsic resistance of IRC 1045 and IRC 1050 to streptomycin at 500 mg/ml and nodules were found to be made up of 100% of previously introduced strains. The potency and competitive ability of the recovered IRC 1045 and IRC 1050 were thus confirmed via the pot experiment and plant reinfection experiment in the greenhouse. At 0—15 cm and 15—30 cm depths 8.0 x 104 and 9.0 x 104 rhizobia/g of soil were recovered respectively in spite of the 10-year fallow period. Biomass production with the three woody legumes revealed Root and Shoot dry weights of the following order of magnitude Senna siamea > L. leucocephala > Senna spectabilis. This report showed the great potential of application of Rhizobium technology in low input sustainable agricultural practice and environmental pollution abatement for non-use of chemical nitrogen fertilizers. (African Journal of Biotechnology: 2002 1(1): 23-27

Efficacy of Collaborative in Improving Learning Outcomes of Graphic Design in Higher Education

Published ArticleThis article presents collaborative design projects done by 28 second-year graphic design students. These projects were identified by the lecturer to be examples of ‘real’ world and ‘hands-on’ projects that are complex, challenging enough and could be impossible for an individual student to complete alone within the limited time frame. These projects not only require students to synthesise their work in a true collaboration, but also to complete work separately and turn it in together at the end. What set these collaborative design projects apart from other graphic design projects are the adept outcome and the amount of control that the students are given over the design

The effectiveness of Information and Communication Technologies (ICTs) in teaching and learning in high schools in Eastern Cape Province

The effectiveness of the use of information and communication technologies (ICTs) in teaching and learning is germane to the recent educational innovations in South Africa. The study examined the level of availability and utilisation of ICT facilities by teachers and students in high schools in Eastern Cape Province, South Africa as well as the factors influencing and challenging its effectiveness. A random sampling technique was adopted to select a sample of 600 (450 students and 150 teachers) for the study. Four research questions were answered with the aid of self-developed instruments tagged Teachers’ Questionnaire on Effectiveness of ICTs in Teaching and Learning (TQEICTTL) and Students’ Questionnaire on Effectiveness of ICTs in Teaching and Learning (SQEICTTL). Frequency and a simple percentage were used to analyse the data obtained. It was revealed that the highest available ICT facilities in all selected schools were mobile phones being used by students to download relevant information on their various courses and exchange ideas and knowledge among other students. It was, therefore, recommended that government play an active role in the effectiveness of the use of ICTs by funding ICTs in schools through training and re-training of teachers and exposure of stakeholders to the relevance of the pedagogy relating to the use of ICTs for teaching and learning.Keywords: effectiveness; high schools; Information Communication Technologies (ICTs); learning; South Africa; students; teachers; teaching and learning; utilisatio

Efficacy of collaborative in improving learning outcomes of graphic design in higher education

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Prevalence of diabetes mellitus and the associated behavioral risks factors among the staff of three secondary schools in Owo, Ondo State, Nigeria

Objective: The prevalence of type 2 Diabetes is associated with significant morbidity and mortality, hence the need for early identification of risk factors. This study, therefore, aimed to determine the prevalence of diabetes mellitus and the associated behavioral risks among secondary school staff in Owo, Ondo State, Nigeria.Methods: A cross-sectional survey of 118 staff at three secondary schools in Owo was conducted using a structured interviewer-administered questionnaire. Demographic and clinical data were obtained as well as fasting or random blood glucose measurements using standard methods. Data were analyzed with SPSS version 21.0.Results: The mean age of participants was 43 ± 8 years, 59.3% were females. Type 2 Diabetes Mellitus was found in 2.8% of the participants, 18.5% were hypertensive, 22.0% were Obese while 25.4% had abdominal obesity. In all, 13.6% smoke cigarette, 35.6% drank alcohol, 49.2% does not add at least a spoonful of vegetable to their meals, 27.1% does not engage in physical exercise while 78.0% do not eat fruits at least once a day. About 58.4% of the respondents had at least one risky behaviour. More male respondents (22.9%) had a self-perceived risk of Diabetes Mellitus (p=0.001), 40.0% of female respondents had abdominal obesity (p<0.001). Correlation (r=0.347) exist between Waist/Hip ratio and random blood glucose, (p=0.012)Conclusion: Despite low prevalence of diabetes mellitus, many had at least one risky behaviour. Intensifying efforts on educating the general population on the risk factors for Diabetes Mellitus and lifestyle modification is important.Keywords: Diabetes Mellitus, behavioural risk factors, lifestyle, blood pressure, obesit

Accumulation of heavy metal pollutants in soil and cassava leaf and their effects on soil microbial population on roadsides in Ogbomoso, Nigeria

Acute toxicity of heavy metals is a rare phenomenon in nature but the intake of sub-­‐lethal doses over an extended period is of great concern. This research investigated the heavy metal concentrations in soil and cassava leaf and assessed the effects of the metals on microbial populations along Ogbomoso-­‐Oyo, high traffic density (HTD) (A) and Ogbomoso-­‐Ife Odan, low traffic density (LTD) (B) roads. The results show that the metals were statistically higher in concentration at A (Pb= 0.53, Cd= 0.57. Cr =0.19, and Zn= 4.67 mg/kg) than B (Pb= 0.36, Cd= 0.40, Cr= 0.12, and Zn= 2.70 mg/kg) road. The mean metal content of cassava leaf indicated that all the metals were higher in the leaf at high traffic density than at low traffic density road. Also, at A 20-­‐30 m recorded lowest heavy metal concentration in the leaf (except Zn = 3.87±0.35 mg/kg) than the distances closer to the road. The same trend was observed at B except that Zn was highest (2.90±0.20 mg/kg) at 10-­‐20 m than 0-­‐10 m and 20-­‐30 m from the road edge. The total microbial count was significantly higher at low traffic density (17.23 Cfug1(x105)) than high traffic density (11.58 Cfug1(x105)). Total microbial count and Total fungi count were found to be lowest at 20-­‐30 m away from the road compared with 0-­‐10 and 10-­‐20 m. The results of this research show that crop cultivation along the roads within 30 m from the roads constitutes a potential source of chronic heavy metal toxicity to the general populace who feed on the crops

Prevalence and clinical relevance of thyroid autoantibodies in patients with goitre in Nigeria

Background: Thyroid autoimmunity was thought to be rare in Africans but there is evidence that its prevalence is increasing. Since undetected autoimmune thyroid disease carries considerable morbidity, this study set out to determine the proportion of patients with goitre who have thyroid autoantibodies and the relationship, if any, between the presence of thyroid autoantibodies, thyroid function and thyroid size. Methods: The study was cross-sectional and conducted over a 12-month period. It involved 100 subjects with goitre and 50 apparently healthy controls without goitre, matched for age and sex. Thyroid dysfunction was assessed by history, clinical examination and biochemical tests, thyroid peroxidase and thyroglobulin antibodies. The size of the thyroid gland was assessed by ultrasound. Results: Fifty-seven percent (57%) of study subjects were euthyroid, 38%were hyperthyroid, while 2%were hypothyroid. The overall prevalence of elevated thyroid peroxidase antibody (TPOAb) in the subjects with goitre was 35% and 8% in the controls (p < 0.001). Elevated thyroglobulin antibody (TgAb) was found in 24% of subjects with goitre and 12% of controls (p = 0.083). Elevated TPOAb was found in 76.3% of subjects who were hyperthyroid, 7% of subjects who were euthyroid and 100% of subjects who were hypothyroid (p < 0.001). Elevated TgAb level was present in 36.8%, 15.8% and 50% of subjects with hyperthyroid, euthyroid and hypothyroid goitre respectively (p = 0.068). A positive correlation was observed between TPOAb and erythrocyte sedimentation rate (r = 0.582, p < 0.001) and TgAb and erythrocyte sedimentation rate (r = 0.176, p = 0.08). The correlation between TPOAb and thyroid volume (r = –0.139, p = 0.167) and that of TgAb and thyroid volume (r = –0.119, p = 0.238) was not significant. Conclusion: The prevalence of thyroid autoantibodies in patients with goitre is high in Nigeria. Thyroid peroxidase antibody ismoreprevalent than thyroglobulin antibody in thyroid disorders and appears to be a better marker than thyroglobulin antibody in detecting autoimmune thyroid dysfunction

Teenage Pregnancy and Home Environment Factors in Ogbomoso, Nigeria

One of the basic social problems affecting the life and future development of the youths these days is the issue of teenage pregnancy. In this study, we relate the problem with factors of home environment using data from household surveys. With correlation and other relationship-depicting statistical analyses, the study observes that incidence of teenage pregnancy is related to residential density, parenthood, heterogeneity of the housing environment, peer group pressures, pornographic videos, among others. The study calls on all stakeholders to be alive to their responsibility, and ensure that a good living and social environment that discourages illicit behaviours is maintained

COMPARATIVE ASSESSMENT OF DIFFERENT DIAGNOSTIC TECHNIQUES IN THE IDENTIFICATION OF MYCOBACTERIUM TUBERCULOSIS IN SUSPECTED CASES OF TUBERCULOSIS

Statement of the Problem: Tuberculosis remains a serious public-health threat in developing countries though it has been eradicated in some advanced countries. This disease constitutes a significant threat to global health, being the second highest cause of morbidity and mortality resulting from infectious agents. Prompt diagnosis of active TB facilitates timely therapeutic intervention and minimizes community transmission. Aim: This study aimed at determining a ‘Point of Care’ diagnostic tool for pulmonary tuberculosis (PTB) by comparing the efficiency of four different PTB diagnostic tools for different age groups. Methodology: Zeihl Nelson (ZN) staining, culture, Gene xpert (GX) and Lipoarabinomanan (LAM) assay were employed in this study The culture method was used for confirmation. Sputum and urine samples were collected from each of 100 patients symptomatically diagnosed of PTB. Findings: Fifty-seven percent of the population was male while 43% were female. Mycobacterium tuberculosis was isolated from 9 (9%) of 100 patients. Similarly, GX detected Mycobacterium tuberculosis in 9 (9%) of the patients while the rate of detection using LAM was 10% and with ZN it was 7%. Gene xpert produced no true or false positive and negative result, LAM had one false positive result and ZN had two false negative results. The maximum time frame to generate result was 25 minutes for LAM, two hours for Gene xpert, eight weeks for culture and two days for ZN. Two positive isolates were observed at the same frequency for age group 21-30 and 31- 40 while age groups 1-10, 10-20, 41-50, 50-60 and above has 1 positive result each. Gene xpert had 98.11% sensitivity while LAM had 96.23% and ZN had 86.79%. The choice of ‘Point of Care’ diagnostic tool is of great concern to clinicians and the general public. Conclusion & Significance: This study identified LAM assay as suitable ‘Point of Care’ diagnostic and an add-on tool for PTB diagnosis because of its relatively high sensitivity and short maximum time frame to generate result compare to other three diagnostic techniques.     &nbsp