1,039 research outputs found
The Ethnic 'Other' in Ukrainian History Textbooks: The Case of Russia and the Russians
This paper examines portrayals of Russia and the Russians in two generations of Ukrainian history textbooks. It observes that the textbooks are highly condemning of Ukraine's main ethnic other in the guise of foreign ruler: the tsarist authorities and the Soviet regime are always attributed dubious and malicious intentions even if there is appreciation for some of their policies. By contrast, the books, certainly those of the second generation, refrain from presenting highly biased accounts of the ethnic other as a national group (i.e. Russians). Instances where negative judgements do fall onto Russians are counterbalanced by excerpts criticizing ethnic Ukrainians or highlighting conflicting interests within the Ukrainian ethnic group. The negative appraisal of the ethnic other as foreign ruler is clearly instrumental for the nation-building project as it sustains a discourse legitimating the existence of Ukraine as independent state. However, recent trends in history education, the paper concludes, suggest that the importance of nurturing patriotism as a national policy objective is diminishing
Microwave Current Imaging in Passive HTS Components by Low-Temperature Laser Scanning Microscopy (LTLSM)
We have used the LTLSM technique for a spatially resolved investigation of
the microwave transport properties, nonlinearities and material inhomogeneities
in an operating coplanar waveguide YBa_2Cu_3O_{7-\delta} (YBCO) microwave
resonator on an LaAlO_3 (LAO) substrate. The influence of twin-domain blocks,
in-plane rotated grains, and micro-cracks in the YBCO film on the nonuniform rf
current distribution were measured with a micrometer-scale spatial resolution.
The impact of the peaked edge currents and rf field penetration into weak links
on the linear device performance were studied as well. The LTLSM capabilities
and its future potential for non-destructive characterization of the microwave
properties of superconducting circuits are discussed.Comment: 8 pages, 9 figures, 2-column format, presented at High Temperature
Superconductors in High Frequency Fields 2004, Journal of Superconductivity
(in press
Investigating human audio-visual object perception with a combination of hypothesis-generating and hypothesis-testing fMRI analysis tools
Primate multisensory object perception involves distributed brain regions. To investigate the network character of these regions of the human brain, we applied data-driven group spatial independent component analysis (ICA) to a functional magnetic resonance imaging (fMRI) data set acquired during a passive audio-visual (AV) experiment with common object stimuli. We labeled three group-level independent component (IC) maps as auditory (A), visual (V), and AV, based on their spatial layouts and activation time courses. The overlap between these IC maps served as definition of a distributed network of multisensory candidate regions including superior temporal, ventral occipito-temporal, posterior parietal and prefrontal regions. During an independent second fMRI experiment, we explicitly tested their involvement in AV integration. Activations in nine out of these twelve regions met the max-criterion (A < AV > V) for multisensory integration. Comparison of this approach with a general linear model-based region-of-interest definition revealed its complementary value for multisensory neuroimaging. In conclusion, we estimated functional networks of uni- and multisensory functional connectivity from one dataset and validated their functional roles in an independent dataset. These findings demonstrate the particular value of ICA for multisensory neuroimaging research and using independent datasets to test hypotheses generated from a data-driven analysis
Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle.
Chaperones TAPBPR and tapasin associate with class I major histocompatibility complexes (MHC-I) to promote optimization (editing) of peptide cargo. Here, we use solution NMR to investigate the mechanism of peptide exchange. We identify TAPBPR-induced conformational changes on conserved MHC-I molecular surfaces, consistent with our independently determined X-ray structure of the complex. Dynamics present in the empty MHC-I are stabilized by TAPBPR and become progressively dampened with increasing peptide occupancy. Incoming peptides are recognized according to the global stability of the final pMHC-I product and anneal in a native-like conformation to be edited by TAPBPR. Our results demonstrate an inverse relationship between MHC-I peptide occupancy and TAPBPR binding affinity, wherein the lifetime and structural features of transiently bound peptides control the regulation of a conformational switch located near the TAPBPR binding site, which triggers TAPBPR release. These results suggest a similar mechanism for the function of tapasin in the peptide-loading complex
State transfer in dissipative and dephasing environments
By diagonalization of a generalized superoperator for solving the master
equation, we investigated effects of dissipative and dephasing environments on
quantum state transfer, as well as entanglement distribution and creation in
spin networks. Our results revealed that under the condition of the same
decoherence rate , the detrimental effects of the dissipative
environment are more severe than that of the dephasing environment. Beside
this, the critical time at which the transfer fidelity and the
concurrence attain their maxima arrives at the asymptotic value
quickly as the spin chain length increases. The transfer
fidelity of an excitation at time is independent of when the system
subjects to dissipative environment, while it decreases as increases when
the system subjects to dephasing environment. The average fidelity displays
three different patterns corresponding to , and . For
each pattern, the average fidelity at time is independent of when the
system subjects to dissipative environment, and decreases as increases when
the system subjects to dephasing environment. The maximum concurrence also
decreases as increases, and when , it arrives at an
asymptotic value determined by the decoherence rate and the structure
of the spin network.Comment: 12 pages, 6 figure
Equation-Free Multiscale Computations in Social Networks: from Agent-based Modelling to Coarse-grained Stability and Bifurcation Analysis
We focus at the interface between multiscale computations, bifurcation theory
and social networks. In particular we address how the Equation-Free approach, a
recently developed computational framework, can be exploited to systematically
extract coarse-grained, emergent dynamical information by bridging detailed,
agent-based models of social interactions on networks, with macroscopic,
systems-level, continuum numerical analysis tools. For our illustrations we use
a simple dynamic agent-based model describing the propagation of information
between individuals interacting under mimesis in a social network with private
and public information. We describe the rules governing the evolution of the
agents emotional state dynamics and discover, through simulation, multiple
stable stationary states as a function of the network topology. Using the
Equation-Free approach we track the dependence of these stationary solutions on
network parameters and quantify their stability in the form of coarse-grained
bifurcation diagrams
Vascular time-activity variation in patients undergoing 123I-MIBG myocardial scintigraphy: implications for quantification of cardiac and mediastinal uptake
For the quantification of cardiac (123)I-metaiodobenzylguanidine (MIBG) uptake, the mediastinum is commonly used as a reference region reflecting nonspecific background activity. However, variations in the quantity of vascular structures in the mediastinum and the rate of renal clearance of (123)I-MIBG from the blood pool may contribute to increased interindividual variation in uptake. This study examined the relationship between changes in heart (H) and mediastinal (M) counts and the change in vascular (123)I-MIBG activity, including the effect of renal function. Fifty-one subjects with ischemic heart disease underwent early (15 min) and late (4 h) anterior planar images of the chest following injection of (123)I-MIBG. Vascular (123)I-MIBG activity was determined from venous blood samples obtained at 2 min, 15 min, 35 min, and 4 h post-injection. From the vascular clearance curve of each subject, the mean blood counts/min per ml at the time of each acquisition and the slope of the clearance curve were determined. Renal function was expressed as the estimated creatinine clearance (e-CC) and the estimated glomerular filtration rate (e-GFR). Relations between H and M region of interest (ROI) counts/pixel, vascular activity, and renal function were then examined using linear regression. Changes in ROI activity ratios between early and late planar images could not be explained by blood activity, the slope of the vascular clearance curves, or estimates of renal function. At most 3% of the variation in image counts could be explained by changes in vascular activity (p = 0.104). The e-CC and e-GFR could at best explain approximately 1.5% of the variation in the slopes of the vascular clearance curve (p = 0.194). The change in measured H and M counts between early and late planar (123)I-MIBG images is unrelated to intravascular levels of the radiopharmaceutical. This suggests that changes in M counts are primarily due to decrease in soft tissue activity and scatter from the adjacent lung
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