Obesity in the elderly: peculiarities of treatment in outpatient practice

Today there is a worldwide trend of population aging, in addition, the proportion of older people with obesity is increasing. In order to adequately manage these patients in the outpatient setting, it is critical to understand the dynamic relationship between body weight, chronic disease prevalence, development of functional disability, life expectancy, and health care costs. While the obesity epidemic has affected people of all age groups, empirical knowledge about the management of obese older people remains largely scarce. Currently, there is no single therapeutic approach to this problem. Weight loss should be treated with caution in people over 60 years of age. The risk of sarcopenia, malnutrition, bone loss, increased risk of falls and injury must be considered, which can lead to an increase in the number of people with disabilities and the associated costs of medical and social care. The analytical review focuses on the relationship between two of the greatest epidemiological trends: aging and obesity. This paper highlights the features of the pathophysiology of obesity in the elderly, the phenomenon of the «obesity paradox». Also from the perspective of evidence-based medicine approaches to the treatment of obesity in the elderly, including surgical interventions aimed at reducing body weight, are analyzed

Vortex shedding behind an obstacle in a channel under transition to turbulence in steady and pulsating flows

© Published under licence by IOP Publishing Ltd. Experimental research and DNS of separated flow over a spanwise semicylindrical rib mounted in a rectangular channel have been performed for the cases of steady and pulsating flow with transition to turbulence. Spiral motion of fluid behind the rib directed from the channel walls towards the channel symmetry plane has been shown to govern the formation of large vortices in the mixing layer starting from some critical Reynolds number. The mechanism of origination of such motion has been hypothesized. The effect of frequency and amplitude of forced freestream pulsations on the vortex pattern behind the rib has been described

Characteristic of the current of acute covid-19 at newborn children

The aim of the study – analysis of clinical and laboratory data of the current of acute COVID-19 at newborn children depending on the mother’s COVID-status.Цель исследования – анализ клинико-лабораторных данных течения острого COVID-19 у новорождённых детей в зависимости от COVID-статуса матерей

Spectral Analysis of a Vortex Wake Behind a Circular Cylinder in a Channel at Moderate Reynolds Numbers

Abstract: Direct numerical simulation is employed to study the complex vortical flow in the wake of a circular cylinder in a rectangular channel at 102. Formation and development of vortices behind bodies are governed by two phenomena: Karman street in the central part of the channel and a pair of spiral peripheral vortices near the channel sidewalls. Both of these phenomena introduce their own disturbances to the flow and can be essential depending on the Reynolds number and geometry of the cross section. Fourier transform yielded spectral density of kinetic energy of velocity fluctuations at fixed sample points in the flow and also revealed the patterns in formation of vortical properties of the wake, including the transition to turbulence and self- oscillations of aerodynamics coefficients of the streamlined body

Formation and turbulent breakdown of large-scale vortical structures behind an obstacle in a channel at moderate Reynolds numbers

© 2019 Author(s). This paper deals with experimental investigation and direct numerical simulation of three-dimensional separated laminar and transitional flows behind a semicircular spanwise rib on a bottom wall of a rectangular channel at Reynolds numbers of up to 480. Particular emphasis is given to the formation mechanism of quasiperiodic large-scale vortex clouds in the mixing layer behind the rib. Vortical structures near the channel axis are formed due to pairing of spiral vortices emerging close to the vertical walls when the corner boundary layers impact on the rib. The effect of the Reynolds number and normalized channel size on the spiraling motion, generation, and shedding of large-scale vortex clouds has been estimated

Vortex Patterns in a Cross Flow Past a Cylinder Near the Channel Wall at Moderate Reynolds Numbers

Abstract: Physical experiment and direct numerical simulation are employed to study a transitional flow of viscous fluid past a spanwise circular cylinder mounted near the wall of a rectangular channel. The Reynolds number varies in the range of 60 to 480. Spiraling tornado-like motion of fluid directed from the sidewalls toward the center of the channel behind the cylinder is discovered. The evolution of this motion with the Reynolds number is outlined. Formation of large-scale vortical structures (analogue of Karman vortex street) and their turbulent breakdown in the cylinder wake are described. The behavior of the drag coefficient of the cylinder and the nearest wall with the Reynolds number is revealed

Vortex shedding behind an obstacle in a channel under transition to turbulence in steady and pulsating flows

© Published under licence by IOP Publishing Ltd. Experimental research and DNS of separated flow over a spanwise semicylindrical rib mounted in a rectangular channel have been performed for the cases of steady and pulsating flow with transition to turbulence. Spiral motion of fluid behind the rib directed from the channel walls towards the channel symmetry plane has been shown to govern the formation of large vortices in the mixing layer starting from some critical Reynolds number. The mechanism of origination of such motion has been hypothesized. The effect of frequency and amplitude of forced freestream pulsations on the vortex pattern behind the rib has been described

Formation and turbulent breakdown of large-scale vortical structures behind an obstacle in a channel at moderate Reynolds numbers

© 2019 Author(s). This paper deals with experimental investigation and direct numerical simulation of three-dimensional separated laminar and transitional flows behind a semicircular spanwise rib on a bottom wall of a rectangular channel at Reynolds numbers of up to 480. Particular emphasis is given to the formation mechanism of quasiperiodic large-scale vortex clouds in the mixing layer behind the rib. Vortical structures near the channel axis are formed due to pairing of spiral vortices emerging close to the vertical walls when the corner boundary layers impact on the rib. The effect of the Reynolds number and normalized channel size on the spiraling motion, generation, and shedding of large-scale vortex clouds has been estimated

Cyclic amp modulation of fc receptor expression on a pre-b cell lymphoma.

© 2014, Pleiades Publishing, Ltd. Results of laboratory research and numerical simulation of 3D separated channel flow behind a semi-cylindrical spanwise rib in laminar and transitional to turbulence flow regimes are presented. Data on dynamics of flow structure and evolution of large-scale vortical structures generated in the obstacle wake zone have been obtained