The Geometric Phase and Gravitational Precession of D-Branes

We study Berry's phase in the D0-D4-brane system. When a D0-brane moves in the background of D4-branes, the first excited states undergo a holonomy described by a non-Abelian Berry connection. At weak coupling this is an SU(2) connection over R^5, known as the Yang monopole. At strong coupling, the holonomy is recast as the classical gravitational precession of a spinning particle. The Berry connection is the spin connection of the near-horizon limit of the D4-branes, which is a continuous deformation of the Yang and anti-Yang monopole.Comment: 23 pages; v3: typos correcte

Interpersonal sensorimotor contingencies: Information-theoretic relevance of subjective experience

Peer reviewedFinal Published versio

Head Trajectory Diagrams for Gait Symmetry Analysis Using a Single Head-Worn IMU

Gait symmetry analysis plays an important role in the diagnosis and rehabilitation of pathological gait. Recently, wearable devices have also been developed for simple gait analysis solutions. However, measurement in clinical settings can differ from gait in daily life, and simple wearable devices are restricted to a few parameters, providing one-sided trajectories of one arm or leg. Therefore, head-worn devices with sensors (e.g., earbuds) should be considered to analyze gait symmetry because the head sways towards the left and right side depending on steps. This paper proposed new visualization methods using head-worn sensors, able to facilitate gait symmetry analysis outside as well as inside. Data were collected with an inertial measurement unit (IMU) based motion capture system when twelve participants walked on the 400-m running track. From head trajectories on the transverse and frontal plane, three types of diagrams were displayed, and five concepts of parameters were measured for gait symmetry analysis. The mean absolute percentage error (MAPE) of step counting was lower than 0.65%, representing the reliability of measured parameters. The methods enable also left-right step recognition (MAPE ≤ 2.13%). This study can support maintenance and relearning of a balanced healthy gait in various areas with simple and easy-to-use devices

The surface accessibility of α-bungarotoxin monitored by a novel paramagnetic probe

The surface accessibility of {alpha}-bungarotoxin has been investigated by using Gd2L7, a newly designed paramagnetic NMR probe. Signal attenuations induced by Gd2L7 on {alpha}-bungarotoxin C{alpha}H peaks of 1H-13C HSQC spectra have been analyzed and compared with the ones previously obtained in the presence of GdDTPA-BMA. In spite of the different molecular size and shape, for the two probes a common pathway of approach to the {alpha}-bungarotoxin surface can be observed with an equally enhanced access of both GdDTPA-BMA and Gd2L7 towards the protein surface side where the binding site is located. Molecular dynamics simulations suggest that protein backbone flexibility and surface hydration contribute to the observed preferential approach of both gadolinium complexes specifically to the part of the {alpha}-bungarotoxin surface which is involved in the interaction with its physiological target, the nicotinic acetylcholine receptor

Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway

We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair. In the current study, we confirmed that Dnmt3b ablation in mesenchymal progenitor cells (MPCs) resulted in impaired endochondral ossification, delayed fracture repair, and reduced mechanical strength of the newly formed bone in Prx1-Cre;Dnmt3bf/f (Dnmt3bPrx1) mice. Mechanistically, deletion of Dnmt3b in MPCs led to reduced chondrogenic and osteogenic differentiation in vitro. We further identified Rbpjκ as a downstream target of Dnmt3b in MPCs. In fact, we located 2 Dnmt3b binding sites in the murine proximal Rbpjκ promoter and gene body and confirmed Dnmt3b interaction with the 2 binding sites by ChIP assays. Luciferase assays showed functional utilization of the Dnmt3b binding sites in murine C3H10T1/2 cells. Importantly, we showed that the MPC differentiation defect observed in Dnmt3b deficiency cells was due to the upregulation of Rbpjκ, evident by restored MPC differentiation upon Rbpjκ inhibition. Consistent with in vitro findings, Rbpjκ blockage via dual antiplatelet therapy reversed the differentiation defect and accelerated fracture repair in Dnmt3bPrx1 mice. Collectively, our data suggest that Dnmt3b suppresses Notch signaling during MPC differentiation and is necessary for normal fracture repair

Sensor node localisation using a stereo camera rig

In this paper, we use stereo vision processing techniques to detect and localise sensors used for monitoring simulated environmental events within an experimental sensor network testbed. Our sensor nodes communicate to the camera through patterns emitted by light emitting diodes (LEDs). Ultimately, we envisage the use of very low-cost, low-power, compact microcontroller-based sensing nodes that employ LED communication rather than power hungry RF to transmit data that is gathered via existing CCTV infrastructure. To facilitate our research, we have constructed a controlled environment where nodes and cameras can be deployed and potentially hazardous chemical or physical plumes can be introduced to simulate environmental pollution events in a controlled manner. In this paper we show how 3D spatial localisation of sensors becomes a straightforward task when a stereo camera rig is used rather than a more usual 2D CCTV camera

Parallel vs. Sequential Belief Propagation Decoding of LDPC Codes over GF(q) and Markov Sources

A sequential updating scheme (SUS) for belief propagation (BP) decoding of LDPC codes over Galois fields, $GF(q)$, and correlated Markov sources is proposed, and compared with the standard parallel updating scheme (PUS). A thorough experimental study of various transmission settings indicates that the convergence rate, in iterations, of the BP algorithm (and subsequently its complexity) for the SUS is about one half of that for the PUS, independent of the finite field size $q$. Moreover, this 1/2 factor appears regardless of the correlations of the source and the channel's noise model, while the error correction performance remains unchanged. These results may imply on the 'universality' of the one half convergence speed-up of SUS decoding