Lower Cretaceous stage durations combining radiometric data and orbital chronology : towards a more stable relative time scale ?

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Sedimentology and sequence stratigraphy of Aquitanian and Burdigalian stratotypes in the Bordeaux area (southwestern France)

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ZnO nanowire / CuSCN heterojunctions for self-powered ultra-violet photodetectors

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Discusion “Depositional dynamics of glaucony-rich deposits in the Lower Cretaceous of the Nice arc, southeast France” (Cretaceous Research 25(2004):179-489), Discussion

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Campagne Transmerou: Etude d'un stade initial d'ouverture au nord de la mer Rouge

New bathymetric, geologic and geophysical data obtained during the R.V. Jean Charcot Transmerou cruise in the northern Red Sea lead to a regional synthesis of the geology of this segment. Detailed surveys of the Mabahiss Deep (near 25 degree 20N) Shaban Deep (Jean Charcot near 26 degree 13N) and the Red Sea-Aqaba Suez, triple junction were made during the cruise. Ship's tracks of Transmerou are represented

The Scedosporium apiospermum species complex: seroprevalence in patients with cystic fibrosis and clinical relevance

International audienceSpecies of the Scedosporium apiospermum complex are emerging fungal pathogens widely recognized now as causing chronic colonization of the airways in patients with cystic fibrosis (CF). Some recent studies performed in Canada 1 and France 2 suggested that the chronic colonization of the airways by another fungal pathogen, Aspergillus fumigatus, may contribute to the progressive deterioration of the lung function observed in some patients. We studied retrospectively the seroprevalence of the S. apiospermum species complex, as a marker of close contact between patient and the fungi, in a large monocentric cohort of CF patients attended in the reference centre in Lyon, France, and evaluated the clinical parameters associated with seropositivity.RESULTS:Serum samples from 373 CF patients were analysed. Serum antibodies against the S. apiospermum species complex were detected in 35 patients (9.4% of studied population). In multivariate analysis, seropositivity to the S. apiospermum species complex was associated only with seropositivity to A. fumigatus.CONCLUSIONS:This study does not suggest an association between sensitization against the S. apiospermum species complex and poorer lung function in patients with CF. Nevertheless, prospective studies are needed to evaluate more precisely the impact of both seropositivity to this species complex and its impact on the airway colonization by these fungi and on evolution of the lung function in patients with CF and the course of the disease.</p