Detection Statistics of Pulse Signals at Declinations from +42o+42^o to +52o+52^o at the Frequency 111 MHz

A search for pulse signals was carried out in a new sky area included in the monitoring program for the search for pulsars and transients. Processing of several months data recorded in six frequency channels with a total bandwidth of 2.5 MHz showed that, on average, 4 pulses per hour are observed in each of the 24 connected stationary beams. Of these pulses, 18.3% are similar to those of pulsars. They are visible in one or two neighboring beams and have a pronounced dispersion shift, that is, they are recorded first at a high and then at a low frequency, which indicates the possible passage of the signal through the interstellar medium. Almost 68% of such detected pulses belong to six known pulsars with dispersion measures from 9 to 141 $pc/cm^3$, and almost all of the remaining pulses are either noise of an unknown nature or artifacts of the proposed pulse separation technique. An additional study of the selected array of 3650 obvious pulsar pulses revealed 13 pulses belonging to four rotating radio transients (RRATs). Their dispersion measures are in the range of 17-51 $pc/cm^3$. A search for regular (periodic) RRAT emission was carried out using power spectra summed over 121 days. Periodic radiation was not detected, but for two RRATs, upper estimates of the periods were obtained from measurements of the time intervals between pulses. The upper estimates of the integrated flux density of the detected RRATs are in the range 2-4 mJy at the frequency 111 MHz.Comment: published in Astronomy Report, translated by Yandex translator with correction of scientific lexis, 6 pages, 3 figures, 2 table

Core acid treatment influence on well reservoir properties in Kazan oil-gas condensate field

The research involves investigation of the influence of hydrochloric acid (HCI-12%) and mud acid ( mixture: HCl - 10 % and HF - 3 %) treatment on the Upper-Jurassic reservoir properties in Kazan oil-gas condensate field wells. The sample collection included three lots of core cylinders from one and the same depth (all in all 42). Two lots of core cylinders were distributed as following: first lot - reservoir properties were determined, and, then thin sections were cut off from cylinder faces; second lot- core cylinders were exposed to hydrochloric acid treatment, then, after flushing the reservoir properties were determined, and thin sections were prepared. Based on the quantitative petrographic rock analysis, involvin 42 thin sections, the following factors were determined: granulometric mineral composition, cement content, intergranular contacts and pore space structure. According to the comparative analysis of initial samples, the following was determined: content decrease of feldspar, clay and mica fragments, mica, clay and carbonate cement; increase of pore spaces while in the investigated samples- on exposure of rocks to acids effective porosity and permeability value range is ambiguous

Detection of two new RRATs at 111 MHz

A search for pulse signals in a area with declinations of +52\degr <\delta <+55\degr was carried out on the LPA LPI radio telescope. When processing ten months of observations recorded in six frequency channels with a channel width of 415 kHz and a total bandwidth of 2.5 MHz, 22 thousand events were found with a pronounced dispersion delay of signals over frequency channels, i.e. having signs of pulsar pulses. It turned out that the found pulses belong to four known pulsars and two new rotating radio transients (RRATs). An additional pulse search conducted in 32-channel data with a channel width of 78 kHz revealed 8 pulses for the transient J0249+52 and 7 pulses for the transient J0744+55. Periodic radiation of transients was not detected. The analysis of observations shows that the found RRATs are most likely pulsars with nullings, where the proportion of nulling is greater than 99.9\%.Comment: published in Astronomy Reports, translated by Yandex translator with correction of scientific lexis, 5 pages, 2 figures, 1 tabl

Luminescent coordination polymers based on Ca²⁺ and octahedral cluster anions [{M₆Clⁱ₈}Clᵃ₆}²⁻ (M = Mo, W) : synthesis and thermal stability studies

Luminescent coordination polymers (CPs) based of inexpensive stable precursors are attractive materials for applications. Here we report the synthesis and evaluation of the stability and photophysical characteristics of the first examples of phosphorescent CPs based on octahedral molybdenum and tungsten cluster anions. Specifically 1D CP trans-[{Ca(OPPh₃)₄}{{M₆Clⁱ₈}Clᵃ₆}]∞ (M = Mo, W) can be obtained either directly at increased temperature or via intermediate phases [cis-Ca(OPPh₃)₄(H₂O)₂][{M₆Clⁱ₈}Clᵃ₆]∙2CH₃CN that are stable at room-temperature, but convert to the titled CP at temperatures above 100 °C

GEMINGA: NEW OBSERVATIONS AT LOW RADIO FREQUENCIES

ABSTRACT. After nearly 10 years, we have succeeded to detect radio emission from Geminga more again. In this report we present new evidence for presence of radio emission from Geminga in the range 42-112 MHz. The observations were carried out on two sensitive transit radio telescopes We used three new digital receivers to detect the pulses and to obtain dynamic spectra.The examples of mean pulse profiles are presented. Exact value of the dispersion measure have been calculated using the simultaneous observations at three frequencies

Application of Basophil Activation Test with Anthraxin for Laboratory ( <I>in vitro</I>) Diagnostics of Anthrax

Demonstrated is the possibility to use in vitro basophil activation test with anthraxin, with registration of the results by means of flow cytometry, for anthrax diagnostics. This approach seems promising as it provides quantitative assessment of sensitization of the organism and does not cause its additional allergization. The duration of the analysis is 1h. The test is suggested for application, as an express one, for early and retrospective laboratory diagnostics of anthrax, estimation of post-vaccinal immunity

Rhythmic Structure of Reading and Cross-Modal Priming Effect of Rhythm on Grammatical Judgements

Ритм является фундаментальным элементом как музыки, так и речи, однако влияние аудиально представленных ритмических паттернов на процессы чтения игнорируется в исследованиях. Здесь мы представляем исследование связанных с событиями потенциалов, проведенное с использованием кросс-модального дизайна. Мы обнаружили увеличение эффекта P600 после регулярной ритмической стимуляции, который был наиболее выражен в правом полушарии. Также мы обнаружили значимое взаимодействие фактора полушария и прайминга. Результаты нашего исследования показывают тесное межмодальное взаимодействие в процессе чтения, а также наличие внутренней ритмической структуры, которая участвует в процессе чтения и может быть синхронизирована с внешней ритмической стимуляцией.Rhythm is a fundamental element of both music and speech, however, the effect of auditorily presented rhythm patterns on reading processes is neglected in the research. Here we present an event-related potentials study conducted using such cross-modal design. We found an increased P600 effect after regular rhythmic stimulation, this effect was the most pronounced in the right hemisphere.We also found a significant interaction between hemispheric factor and priming. These results suggest tight intermodal connections in the reading process as well as the existence of an internal rhythmic structure which is both involved in the reading process and might be synchronized with external rhythmic stimulation

STUDYING DEVELOPMENT OF POST-VACCINAL CELLULAR IMMUNITY AGAINST BRUCELLOSIS BY MEANS OF LYMPHOCYTE <i>IN VITRO</i> TESTS USING AN EXPERIMENTAL ANTIGENIC COMPLEX

Regulatory framework and methodological approaches to evaluation of immunological effects of vaccination against brucellosis are not established, and the degree of immunological post-vaccinal rearrangement is not yet developed. Due to leading role of cellular immunity in formation of immune protection against brucellosis, evaluation the cellular response in response to antigenic stimulation may be considered the most informative and objective approach to analysis of immune changes in the body during vaccination. In order to develop the most diagnostically informative methods for design of antigen-stimulation cell tests in vitro, a careful selection of a stimulating agent (antigen) is required, which should have a sufficient activating potential, thus providing specificity of reaction under in vitro conditions. The aim of the present study is to study the in vitro specific activity of a protein-polysaccharide antigenic complex from the Brucella abortus 19 BA strain (BrAg), and an opportunity of its application in order to assess the formation of post-vaccinal cellular immunity against brucellosis.The study was performed with white laboratory mice (n = 50) immunized with the Brucella abortus 19 BA strain. The control group (n = 50) consisted of laboratory mice that received a sterile saline solution in a volume of 0.5 ml. Blood samples were taken from immunized and control animals before vaccination, and 7, 14, 21, and 30 days after immunization. By means of flow cytometry, the activation molecules CD25, CD69, MHC II and CD95, expressed on T lymphocytes (CD3+CD69+, CD3+CD25+, CD3+CD95+, CD3+MHC+) were determined. To observe the development of immunity, the intensity of expression of T lymphocyte activation markers was calculated using the stimulation quotient. BrAg was used for specific in vitro stimulation of T lymphocytes. The liquid brucellosis allergen (brucellin) was used as an antigen for comparison, when studying opportunity of BrAg usage for assessing the postvaccinal immunity development.The following results were obtained: BrAg has pronounced specific activity, it did not cause non-specific in vitro reactions (activation) of T lymphocytes, thus enabling its application as a test antigen when evaluating development of adaptive vaccine immunity against brucella.Experimental testing of brucellosis antigen for carrying out the in vitro antigen-stimulated cellular reactions, aiming for evaluation of post-vaccinal immunity development against brucellosis, showed that the usage of BrAg promotes increase in diagnostic sensitivity of cellular reactions under in vitro experimental conditions. The applied experimental antigen is a quite promising tool for development of laboratory algorithms for brucellosis diagnostics, and assessment of actual vaccination efficiency in cohorts previously vaccinated against brucellosis

Brucellosis: Trends in the Development of Situation in the World and Forecast for 2022 in the Russian Federation

An analysis of trends in the development of situation on brucellosis in the world over past decade and the data on the main risk factors for the occurrence of epidemiological complications regarding this infection in various regions of the world are provided in the paper. An expert assessment of the current epizootiological and epidemiological situation on brucellosis, the coverage of population and animals with immunization in the Russian Federation is given. Over 9 months of 2021, 210 potentially hazardous as regards brucellosis in cattle areas and 24 sites – as regards brucellosis in small ruminants – were registered in Russia. Compared to the same period in 2020, there was a decrease in the number of newly identified hazardous sites for bovine brucellosis by 35.8 % (117 areas). However, long-term upward trend in epizootiological adversity for bovine brucellosis in Russia persists. The epidemiological situation on brucellosis in the country for the period of 2012–2021 is characterized as unfavorable. Decrease in the number of newly detected human brucellosis cases (by 25.1 % of long-term average values) is observed against the background of persistent unfavorable epizootic conditions for brucellosis among epidemiologically significant species of small ruminants and cattle in regions with developed animal husbandry. In 2021, clusters of human cases were registered in the Republic of Dagestan and Penza Region. In the Republic of Dagestan, against the background of aggravation of epizootiological and epidemiological situation on brucellosis, there was also an alarming trend towards prevalence of a relatively high incidence among minors. The proportion of cases of brucellosis among children under the age of 17 in the Republic amounted to 60.3 % of the total number of minors with newly diagnosed brucellosis in Russia over the past 10 years. Taking into account current epizootic, epidemic situations and the long-term dynamics of the development of situation on  brucellosis in the Russian Federation, the incidence of brucellosis among the population  is predicted to be 10–15 % lower than the average long-term values – 0.18–0.20 per 100000 of the population – in 2022. The number of human cases of brucellosis can range from 250 to 300

К ВОПРОСУ О СТАНДАРТИЗАЦИИ СЫРЬЯ ЭСТРАГОНА

Tarragon (Artemisia dracunculus L.) is a spicy aromatic culture, perspective to use in the food and medical industry. In the collection of aromatic and medicinal plants of the Nikita Botanical Gardens, tarragon is represented by two varieties: Isumrud and Travnevy. The Isumrud variety is characterized by a high content of essential oil (0.6% of the wet weight) of the methylchavicol chemotype (the main component of the essential oil is methylchavicol, whose mass fraction is up to 91%) and is perspective to use not only as a spice, but also in medicine as a reducing facilities. The variety Travnevy contains only 0.1% of the essential oil from the wet mass of the sabineno-elemicin chemotype (the main components of the essential oil are sabinen (40.0%) and trans-from-iso-elemicin – 26.1%), characterized by high productivity of the aerial mass (12 kg/m2 ), the main direction of use in the food industry as a spice. Due to the lack of requirements for dry raw tarragon, we have developed a draft technical specifications for dry crushed tarragon raw materials TS 01.28.30-009-01579640-2018. Specifications apply to dried whole and crushed raw materials, intended for the manufacture of water and water-alcohol infusions, as a source of biologically active substances, as a component for seasonings to meat, fish dishes, for use in cooking, as well as in the production of alcohol and soft drinks. The main physicochemical indicators of whole and crushed tarragon raw materials (type, size, smell, taste, mass fraction of essential oil, impurities, moisture, ash) are presented.Эстрагон (Artemisia dracunculus L.) – пряно-ароматическая культура, перспективная для применения в пищевой и фармацевтической промышленности. В коллекции ароматических и лекарственных растений Никитского ботанического сада эстрагон представлен двумя сортами собственной селекции: Изумруд и Травневый. Сорт Изумруд характеризуется высоким содержанием эфирного масла (0,6% от сырой массы) метилхавиколового хемотипа (основным компонентом эфирного масла является метилхавикол, массовая доля которого составляет до 91%) и перспективен для использования не только как пряность, но и в медицине в качестве общеукрепляющего средства. Сорт Травневый содержит всего 0,1% эфирного масла от сырой массы сабиненово-элемицинового хемотипа (основные компоненты эфирного масла сабинен (40,0%) и трансизо-элемицин – 26,1%), характеризуется высокой продуктивностью надземной массы (12 кг/м2), основное направление использования – в пищевой промышленности в качестве пряности. В связи с отсутствием требований к сухому сырью эстрагона нами разработан проект технических условий на сухое измельченное сырье эстрагона ТУ 01.28.30-009-01579640-2018. Технические условия распространяются на высушенное цельное и измельченное сырье, предназначенное для изготовления водных и водно-спиртовых настоев, как источника биологически активных веществ, в качестве компонента для приправ к мясным, рыбным блюдам, для использования в кулинарии, а также при производстве спиртных и прохладительных напитков. Приведены основные физико-химические показатели цельного и измельченного сырья эстрагона (вид, размер, запах, вкус, массовая доля эфирного масла, примесей, влаги, золы)