Assessing acute itch intensity : general labelled magnitude scale is more reliable than classic visual analogue scale

The reliable measurement of itch intensity is crucial, both in research as well as clinical contexts. For example, when the reliability of a measurement scale is unknown, it is impossible to determine whether a patient has changed sufficiently to be confident that the change is beyond that which could be attributed to measurement error (1). One factor that might influence the reliability of measurements is the type of rating scale used to assess itch intensity. Previous research (2-4) has documented the retest reliability of different rating scales for assessing chronic itch intensity. However, a retest reliability analysis of rating scales for acute experimental itch, induced using substances such as histamine or cowhage, is currently lacking. Here, we compare the test-retest reliability of three rating scales commonly used for this purpose. First, we considered the visual analogue scale in its classic form (cVAS), where participants indicate itch intensity on a line ranging from 0 (no itch) to 100 (the most intense itch imaginable). Second, we included a variant of the VAS, where an additional ‘Scratch Threshold’ marker is set at 33% (tVAS,5), defined as itching strong enough to be scratched (6). Finally, we considered the general Labelled Magnitude Scale (gLMS,7), where participants judge the magnitude of itch on a line with quasilogarithmically placed labels of “no sensation” at 0, “barely detectable” at 1, “weak” at 6, “moderate” at 17, “strong” at 35, “very strong” at 53 and “strongest imaginable sensation” at 100. Thus, all three scales have an identical range, but differ in the type and number of verbal labels provided

Locally Polynomially Bounded Structures

We prove a theorem which provides a method for constructing points on varieties defined by certain smooth functions. We require that the functions are definable in a definably complete expansion of a real closed field and are locally definable in a fixed o-minimal and polynomially bounded reduct. As an application we show that in certain o-minimal structures definable functions are piecewise implicitly defined over the basic functions in the language.Comment: Change of titl

Fuel subsidies versus market power : is there a countervailing second-best optimum?

Fuel subsidies distort end-use prices below cost, resulting in overconsumption and huge environmental cost. On the other hand, the mark-up over cost due to the exercise of market power results in the social loss of consumer surplus. We open a new line of inquiry into the potential for a market-based solution from these two countervailing forces: can the two offsetting distortions conceivably achieve a second- best optimum? Relying on dynamic panel techniques and gasoline market data for 68 developing countries, we uncover an excessive second-best subsidy offset to market power mark-up on the order of 4.5. Our results indicate that the potential for policy failure strongly exceeds the potential for market failure in our model, and gasoline prices across our sample may not be aligned with vigorous anti-climate change policy

An evaluation of superminicomputers for thermal analysis

The feasibility and cost effectiveness of solving thermal analysis problems on superminicomputers is demonstrated. Conventional thermal analysis and the changing computer environment, computer hardware and software used, six thermal analysis test problems, performance of superminicomputers (CPU time, accuracy, turnaround, and cost) and comparison with large computers are considered. Although the CPU times for superminicomputers were 15 to 30 times greater than the fastest mainframe computer, the minimum cost to obtain the solutions on superminicomputers was from 11 percent to 59 percent of the cost of mainframe solutions. The turnaround (elapsed) time is highly dependent on the computer load, but for large problems, superminicomputers produced results in less elapsed time than a typically loaded mainframe computer

An evaluation of superminicomputers for thermal analysis

The use of superminicomputers for solving a series of increasingly complex thermal analysis problems is investigated. The approach involved (1) installation and verification of the SPAR thermal analyzer software on superminicomputers at Langley Research Center and Goddard Space Flight Center, (2) solution of six increasingly complex thermal problems on this equipment, and (3) comparison of solution (accuracy, CPU time, turnaround time, and cost) with solutions on large mainframe computers

Public Attitudes Toward Crime and Incarceration in Finland

The following paper provides insights into Finland’s criminal justice system and discusses the policies that emphasize using prison for rehabilitation, not merely for punishment. These methods of prevention and rehabilitation, in conjunction with correctional and educational staff within and outside the prison walls, have contributed to consistently low recidivism rates in Finland. This study discusses many ideological similarities between public opinions towards criminals and crime in Finland and the United States. Like Americans, Finns are intolerant of crime and violence, yet open to the idea of alternative forms of punishment, especially for non-violent and juvenile offenders. People in both countries tend to believe criminals are not born into a criminal life and that societal factors play a role in creating criminal behavior. This study sheds light on both the public support for ex-offenders’ rehabilitation in Finland and the extent to which Americans support alternative forms of punishment. It also provides a narrative of the disconnect between public opinion and what public officials think public opinion is

Preliminary design of a geologic sample acquisition and transport device Final report, May - Oct. 1965

Design concept for breadboard model of geological sample and transport device for Surveyor projec

Somatic Cell Counts (Leucocyte Counts) A Standard of Milk Acceptability

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