Precise MS-bar light-quark masses from lattice QCD in the RI/SMOM scheme

We compute the conversion factors needed to obtain the MS-bar and RGI up, down, and strange-quark masses at next-to-next-to-leading order from the corresponding parameters renormalized in the recently proposed RI/SMOM and RI/SMOM_gamma_mu renormalization schemes. This is important for obtaining the MS-bar masses with the best possible precision from numerical lattice-QCD simulations, because the customary RI(')/MOM scheme is afflicted with large irreducible uncertainties both on the lattice and in perturbation theory. We find that the smallness of the known one-loop matching coefficients is accompanied by even smaller two-loop contributions. From a study of residual scale dependences, we estimate the resulting perturbative uncertainty on the light-quark masses to be about 2% in the RI/SMOM scheme and about 3% in the RI/SMOM_gamma_mu scheme. Our conversion factors are given in fully analytic form, for general covariant gauge and renormalization point. We provide expressions for the associated anomalous dimensions.Comment: Added results for the RI/SMOM_gamma_mu scheme and anomalous dimensions; typos fixed (results unchanged); added reference

QCD Corrections to Vector-Boson Fusion Processes in Warped Higgsless Models

We discuss the signatures of a representative Higgsless model with ideal fermion delocalization in vector-boson fusion processes, focusing on the gold- and silver-plated decay modes of the gauge bosons at the CERN-Large Hadron Collider. For this purpose, we have developed a fully-flexible parton-level Monte-Carlo program, which allows for the calculation of cross sections and kinematic distributions within experimentally feasible selection cuts at NLO-QCD accuracy. We find that Kaluza-Klein resonances give rise to very distinctive distributions of the decay leptons. Similar to the Standard Model case, within the Higgsless scenario the perturbative treatment of the vector-boson scattering processes is under excellent control.Comment: 22 pages, 20 figure

Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer

Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein that is frequently overexpressed in a variety of carcinomas. This pan-carcinoma antigen has served as the target for a plethora of immunotherapies. Innovative therapeutic approaches include the use of trifunctional antibodies (trAbs) that recruit and activate different types of immune effector cells at the tumour site. The trAb catumaxomab has dual specificity for EpCAM and CD3. In patients with malignant ascites, catumaxomab significantly increased the paracentesis-free interval, corroborating the high efficacy of this therapeutic antibody. Here, we characterised the monoclonal antibody (mAb) HO-3, that is, the EpCAM-binding arm of catumaxomab. Peptide mapping indicated that HO-3 recognises a discontinuous epitope, having three binding sites in the extracellular region of EpCAM. Studies with glycosylation-deficient mutants showed that mAb HO-3 recognised EpCAM independently of its glycosylation status. High-affinity binding was not only detected for mAb HO-3, but also for the monovalent EpCAM-binding arm of catumaxomab with an excellent KD of 5.6 × 10−10 M. Furthermore, trAb catumaxomab was at least a 1000-fold more effective in eliciting the eradication of tumour cells by effector peripheral blood mononuclear cells compared with mAb HO-3. These findings suggest the great therapeutic potential of trAbs and clearly speak in favour of EpCAM-directed cancer immunotherapies

Zur Verbreitung, Biologie und Ökologie der Grabwespen (Hym. Sphec.) in der näheren Umgebung von Halle/S. mit speziellen Bemerkungen über Mellinus arvensis L.

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Sublethal injury and Viable but Non-culturable (VBNC) state in microorganisms during preservation of food and biological materials by non-thermal processes

The viable but non-culturable (VBNC) state, as well as sublethal injury of microorganisms pose a distinct threat to food safety, as the use of traditional, culture-based microbiological analyses might lead to an underestimation or a misinterpretation of the product's microbial status and recovery phenomena of microorganisms may occur. For thermal treatments, a large amount of data and experience is available and processes are designed accordingly. In case of innovative inactivation treatments, however, there are still several open points with relevance for the investigation of inactivation mechanisms as well as for the application and validation of the preservation processes. Thus, this paper presents a comprehensive compilation of non-thermal preservation technologies, i.e., high hydrostatic pressure (HHP), pulsed electric fields (PEFs), pulsed light (PL), and ultraviolet (UV) radiation, as well as cold plasma (CP) treatments. The basic technological principles and the cellular and molecular mechanisms of action are described. Based on this, appropriate analytical methods are outlined, i.e., direct viable count, staining, and molecular biological methods, in order to enable the differentiation between viable and dead cells, as well as the possible occurrence of an intermediate state. Finally, further research needs are outlined

Discovery of an Optical Jet in the BL Lac Object 3C 371

We have detected an optical jet in the BL Lac object 3C 371 that coincides with the radio jet in this object in the central few kpc. The most notable feature is a bright optical knot 3 arcsec (4 kpc) from the nucleus that occurs at the location where the jet apparently changes its direction by ~30 degrees. The radio, near-infrared and optical observations of this knot are consistent with a single power-law spectrum with a radio-optical spectral index alpha = -0.81. One possible scenario for the observed turn is that the jet is interacting with the material in the bridge connecting 3C 371 to nearby galaxies and the pressure gradient is deflecting the jet significantly.Comment: 11 pages, LaTeX, 4 figures (1 eps, 3 gifs), accepted for publication in ApJ Letter

Light trapping gratings for solar cells an analytical period optimization approach

Solar cells can harvest incident sunlight very efficiently by utilizing grating based light trapping. As the working principle of such gratings strongly depends on the number as well as the propagation directions of the diffraction orders, the grating period is a key parameter. We present an analytical model for optimizing the grating period, focusing on its impact on light path enhancement and outcoupling probability. Based on the presented model, we formulate guidelines to maximize light trapping in state of the art high end solar cells. The model increases the understanding of the grating performance in systems like the III V Si triple junction solar cell achieving record efficienc

Cellulose hydrolysis-hydrogenolysis to ethyleneglycol and propyleneglycol over Ru and heteropolyacid catalysts

Еthylene and propylene glycols (EG and PG) are widely used in industry to produce cooling systems and other valuable chemical products. But PG is non-toxic, therefore it is used in industries where EG can not be used: pharmaceutical, food, etc. This polyols produced by "one-pot" method, which is one of the promising and effective methods for producing alcohols from cellulose under harsh conditions. The purpose of this study was to determine the optimal composition of the solid bifunctional catalyst and the conditions of its preparation for the hydrolysis-hydrogenolysis of cellulose. Catalists are Ru-HPA/ZrO[2], RuHPA/Nb[2]O[5] and Ru/CsHPK. As a result of the study, the most promising catalyst system is 1%Ru/Cs[3.5]H[0.5]SiW[12]O[40]. In the presence of 1%Ru/CsHPA, the yield of 25% EG and 11% PG was detected (EG and PG selectivity is 60 and 27%). The activity of the catalysts was studied in the presence of Ca(OH)[2]