Bilateral calf chronic compartment syndrome in an elderly male: a case report

Leg pain is a common presentation to the outpatient department. Bilateral calf chronic compartment syndrome is a rare cause of bilateral calf pain. Although this condition has been well documented in young athletes, it has rarely been reported in the elderly. We present the case of a 68-year-old male bodybuilder with bilateral calf chronic compartment syndrome, describe the presentation and evaluation of the condition, and provide a review of the literature herewith

A Parallel, Unstructured-Mesh Methodology for Device-Scale Combustion Calculations

RŽsumŽ Ñ MŽthodologie parall le avec maillages destructurŽs pour des calculs de combustion-effet du nombre de processeurs Ñ Los Alamos National Laboratories dŽveloppent une mŽthodologie de calcul parall le, destructurŽe et en volumes finis pour la mŽcanique des fluides numŽrique. Cette mŽthodologie est implantŽe dans le code Chad (Computational Hydrodynamics for Advanced Design). Dans cet article, on donne un aper u de la mŽthodologie numŽrique de Chad, et une prŽsentation des rŽsultats de calculs parall les d'Žcoulements dans un moteur Diesel ˆ 4 soupapes. L'efficacitŽ en fonction du nombre de processeurs est ŽtudiŽe. Abstract Ñ A Parallel, Unstructured-Mesh Methodology for Device-Scale Combustion Calculations Ñ Los Alamos National Laboratories is developing a parallel, unstructured-mesh, finite-volume CFD methodology for the simulation of chemically reactive flows in complex geometries. The methodology is embodied in the Chad (Computational Hydrodynamics for Advanced Design) code. In this report we give an overview of the Chad numerical methodology and present parallel scaling results for calculations of flows in a four-valve Diesel engine

Differences in genetic diversity of noncapsulated Haemophilus influenzae from various diseases.

No description supplie

Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death

OBJECTIVE The aim of this study was to investigate tumor recurrence after liver transplantation for hepatocellular carcinoma (HCC), with and without hypothermic oxygenated liver perfusion (HOPE) before transplantation. PATIENTS AND METHODS We analyzed all liver recipients with HCC, transplanted between January 2012 and September 2019 with donation after circulatory death (DCD) livers after previous end-ischemic HOPE-treatment (n = 70, Center A). Tumor parameters and key confounders were compared to consecutive recipients with HCC, transplanted during the same observation period with an unperfused DBD liver (n = 70). In a next step, we analyzed unperfused DCD (n = 70) and DBD liver recipients (n = 70), transplanted for HCC at an external center (Center B). RESULTS Tumor parameters were not significantly different between HOPE-treated DCD and unperfused DBD liver recipients at Center A. One-third of patients were outside established tumor thresholds, for example, Milan criteria, in both groups. Despite no difference in tumor load, we found a 4-fold higher tumor recurrence rate in unperfused DBD livers (25.7%, 18/70), compared to only 5.7% (n = 4/70) recipients with tumor recurrence in the HOPE-treated DCD cohort (P = 0.002) in Center A. The tumor recurrence rate was also twice higher in unperfused DCD and DBD recipients at the external Center B, despite significant less cases outside Milan. HOPE-treatment of DCD livers resulted therefore in a 5-year tumor-free survival of 92% in HCC recipients, compared to 73%, 82.7%, and 81.2% in patients receiving unperfused DBD or DCD livers, from both centers. CONCLUSION We suggest that a simple machine liver perfusion approach appears advantageous to protect from HCC recurrence after liver transplantation, despite extended tumor criteria