The photogeological characteristics of carboniferous limestone

Imperial Users onl

Preparation of hydroxyapatite/silk protein thin film implant surfaces, investigation of their microstructural properties and model protein interactions

Thesis (Doctoral)--Izmir Institute of Technology, Chemical Engineering, Izmir, 2009Includes bibliographical references (leaves: 258-267)Text in English; Abstract: Turkish and Englishxx, 267 leavesBiocompatible hydroxyapatite (HAp) coatings of load bearing metallic in vivo hard tissue implants act as local scaffolds for enhanced osteoconduction, providing fast bone apposition and cementless fixation. In this study, in an attempt to exploit the potential of hydroxyapatite as a carrier of bone morphogenetic proteins for post operative accelerated healing, and implant durability, the tailored microstructural properties, and protein adsorption capabilities of thin film hydroxyapatite implant surfaces were investigated.A novel particulate sol method was used to fabricate HAp thin films on bioinert glass, and Ti6Al4V substrates by dip and spin coating. The microstructural characterization of the thin films was carried out by SEM/EDX, AFM, XRD, and FTIR, and their surface roughness, Vickers hardness and adhesion strength were determined. The effects of silk fibroin and sericin thin film layers on the HAp film microstructure, and model protein (bovine serum albumin, BSA) adsorption behavior (by the size exclusion HPLC method) were investigated. The minimum threshold solid content of the suspensions was determined as 15% by weight for a continuous HAp film structure. The silk sericin and fibroin intermediate layers drastically improved homogeneity of the HAp layer. The BSA adsorption of the glass/sericin/commercial-HAp film was 2.6 ug/cm2, more than twice of the glass/commercial-HAp, and glass/sericin/dry-milled-HAp films, evidencing the effectiveness of surface micro/nano topographical structure as well as chemical structure. The XRD patterns of spin coated commercial-HAp films on Ti6Al4V pointed out to a particular crystal orientation which increased the positive degree of cooperativity between HAp and proteins during adsorption or deposition

Preparation of hydroxyapatite/silk protein thin film implant surfaces, investigation of their microstructural properties and model protein interactions

Thesis (Doctoral)--Izmir Institute of Technology, Chemical Engineering, Izmir, 2009Includes bibliographical references (leaves: 258-267)Text in English; Abstract: Turkish and Englishxx, 267 leavesBiocompatible hydroxyapatite (HAp) coatings of load bearing metallic in vivo hard tissue implants act as local scaffolds for enhanced osteoconduction, providing fast bone apposition and cementless fixation. In this study, in an attempt to exploit the potential of hydroxyapatite as a carrier of bone morphogenetic proteins for post operative accelerated healing, and implant durability, the tailored microstructural properties, and protein adsorption capabilities of thin film hydroxyapatite implant surfaces were investigated.A novel particulate sol method was used to fabricate HAp thin films on bioinert glass, and Ti6Al4V substrates by dip and spin coating. The microstructural characterization of the thin films was carried out by SEM/EDX, AFM, XRD, and FTIR, and their surface roughness, Vickers hardness and adhesion strength were determined. The effects of silk fibroin and sericin thin film layers on the HAp film microstructure, and model protein (bovine serum albumin, BSA) adsorption behavior (by the size exclusion HPLC method) were investigated. The minimum threshold solid content of the suspensions was determined as 15% by weight for a continuous HAp film structure. The silk sericin and fibroin intermediate layers drastically improved homogeneity of the HAp layer. The BSA adsorption of the glass/sericin/commercial-HAp film was 2.6 ug/cm2, more than twice of the glass/commercial-HAp, and glass/sericin/dry-milled-HAp films, evidencing the effectiveness of surface micro/nano topographical structure as well as chemical structure. The XRD patterns of spin coated commercial-HAp films on Ti6Al4V pointed out to a particular crystal orientation which increased the positive degree of cooperativity between HAp and proteins during adsorption or deposition

Nusairis/Arab Alawites Between Change and Taqiyya

Nusairis/Arab Alawites has existed in our country’s Mediterranean coast for many years with their distinctive social and cultural structure, religious beliefs, and ethnical differences. In recent times, the approach towards this group is more described with their upper identity as Shia. However, in their ancient tradition while they were named as Nusairis, lately due to conjuncture, ideological and theo-strategical reasons, they are called and grouped with different names. This could be a result of today’s global change wind and taqiyya which is a strong and very effective doctrine in Nusairi belief. While this study covers the appearance of Nusairis in Turkey, its method consists of handling theological, historical and anthropological studies towards this topic in a qualitative way. The purpose of the study is to classify the identity representation of Nusairis with consideration of interaction between taqiyya and global change. According to this classification, Nusairis in Turkey can be listed as following groups; a) Republican with laicism identity b) Hittite Turks c) from being an outsider in the community to becoming Jaafari Nusairi d) Nusairis that are resistant to tradition e) Turkish – Shia relationship/ unrelationship f) lost Christians. As a result, defining Nusairis with Shiia upper identity brings many problems within, also there are many other fractions continue their traditional and theo-strategical existence within community which has different aspects of religious, history, sociology and culture

Effects of single cycle binaural beat duration on auditory evoked potentials

Binaural beat (BB) illusions are experienced as continuous central pulsations when two sounds with slightly different frequencies are delivered to each ear. It has been shown that steady-state auditory evoked potentials (AEPs) to BBs can be captured and investigated. The authors recently developed a new method of evoking transient AEPs to binaural beats using frequency modulated stimuli. This methodology was able to create single BBs in predetermined intervals with varying carrier frequencies. This study examines the effects of the BB duration and the frequency modulating component of the stimulus on the binaural beats and their evoked potentials. Normal hearing subjects were tested with a set of four durations (25, 50, 100, and 200 ms) with two stimulation configurations, binaural dichotic (binaural beats) and diotic (frequency modulation). The results obtained from the study showed that out of the given durations, the 100 ms beat, was capable of evoking the largest amplitude responses. The frequency modulation effect showed a decrease in peak amplitudes with increasing beat duration until their complete disappearance at 200 ms. Even though, at 200 ms, the frequency modulation effects were not present, the binaural beats were still perceived and captured as evoked potentials

Metabolik Alkalozla Prezente Olan Diyabetik Ketoasidoz

Diabetic Ketoacidosis Presenting withMetabolic AlkalosisMetabolik Alkalozla Prezente Olan Diyabetik KetoasidozMustafa Erdoğan1, Seydahmet Akın1, Sinan Kazan2, Mehmet Aliustaoğlu1, Özcan Keskin1&nbsp;Giriş: Diyabet sıklığı ve prevelansı giderek artan bir hastalıktır.Diyabetin kronik ve akut komplikasyonları morbidite, mortalite veartmış sağlık harcamalarına neden olmaktadır. Diyabetin önemlibir akut komplikasyonu genellikle ciddi organik asidoz ile ortayaçıkan diyabetik ketoasidozdur.Olgu Sunumu: Vakamızda diyabetik alkaloz ile tanı konan birdiyabetik ketoasidoz vakasını sunuyoruz.Sonuç: Biz bu vaka üzerinden, acil şartlarda miks kan gazıbozukluklarının değerlendirilmesine dikkat çekmeyi amaçladık.Anahtar Kelimeler: Diyabetik ketoasidoz, metabolik alkaloz,metabolik asidoz&nbsp;Diabetic Ketoacidosis Presenting withMetabolic AlkalosisMetabolik Alkalozla Prezente Olan Diyabetik KetoasidozMustafa Erdoğan1, Seydahmet Akın1, Sinan Kazan2, Mehmet Aliustaoğlu1, Özcan Keskin1&nbsp;Introduction: Diabetes is a disease with an increasing incidenceand prevalence. Chronic and acute complications of diabetescause mortality, morbidity, and increased health expenditure. Amajor acute complication of diabetes usually presenting withserious organic acidosis is diabetic ketoacidosis.Case Report: We report the case of a patient with diabeticketoacidosis case who presented with diabetic metabolic alkalosis.Conclusion: Through this case, we aimed to draw attention tothe assessment of mixed acid–base disturbances in emergencydepartments.Keywords: Diabetic ketoacidosis, metabolic alkalosis, metabolicacidosis&nbsp;</div

Doplor Sleep: Monitoring Hospital Soundscapes for Better Sleep Hygiene

Good sleep is conducive to the recovery process of hospital patients – and yet, in many wards, sleep duration and quality can often be suboptimal, in part due to modifiable hospital-related sounds and noises. At the neurological ward of the Reinier de Graaf hospital in Delft, the Netherlands, we developed and evaluated a prototype information exchange system to raise awareness of specific sounds as disturbing patients’ sleep. The system both classifies different relevant sound events and tracks sleep quality (using a Fitbit device). This information is then visualized for patients and staff to present the influence of the soundscape on patients’ sleep hygiene in a friendly and comprehensive way. We discuss the design process, including a context study and various evaluations of the technology, interface, and created affordances. Our initial findings indicate that visualizing hospital soundscapes may, indeed, support both patients and staff in their efforts towards better sleep hygiene