102 research outputs found

    The Evolution of E-Books

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    The Invariant Algorithm for Identification and Detection of Multiple Gas Plumes and Weak Releases

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    The ability to detect and identify gaseous effluents is a problem that has been pursued with limited success. It has been shown to bepossible using the Invariant algorithm on synthetic hyperspectralscenes with a strong single gas release. That however, is a veryspecific case and leaves room for further investigation. This studylooks at more realistic detection and release scenarios. Ourimplementation of the Invariant algorithm uses Singular ValueDecomposition (SVD) to select basis vectors from a subspace of targetgases in conjunction with a Generalized Likelihood Ratio Test (GLRT) to determine on a pixel by pixel basis how ``like the target gas each pixel is. The target gases are modeled in the image radiance space including atmospheric effects. Target spectra are modeled in both emission and absorption. This study investigates how well weak plumes are detected. Also, there will be a test of a mixed gas in a strong plume release. Finally, a situation where a weak multiple gas release will be discussed. Synthetic hyperspectral imagery in the long wave infrared region (LWIR) of the electromagnetic spectrum will be the predominate data used in this study. This algorithm has been found to be applicable for these detection and identification scenarios

    Quality indicators of diabetes care: an example of remote-area Aboriginal primary health care over 10 years

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    To describe service characteristics of Derby Aboriginal Health Service (DAHS) and document diabetes management activities and intermediate clinical outcomes for Aboriginal patients with type 2 diabetes

    On the Differences Between Blood and Red Ink: A Second Look at the Policy Arguments for the Abrogation of the Economic Loss Rule in Consumer Litigation

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    The long-running debate concerning the scope of the economic loss rule\u27 presents issues which are important in themselves and as illustrations of broader questions.2 Litigants and commentators champion the opposing schools of thought through close analysis of precedent;3 the exchange of views as to the nature of tort law and contract law;4 and occasionally, economic analysis

    Identification and Detection of Gaseous Effluents from Hyperspectral Imagery Using Invariant Algorithms

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    The ability to detect and identify effluent gases is, and will continue to be, of great importance. This would not only aid in the regulation of pollutants but also in treaty enforcement and monitoring the production of weapons. Considering these applications, finding a way to remotely investigate a gaseous emission is highly desirable. This research utilizes hyperspectral imagery in the infrared region of the electromagnetic spectrum to evaluate an invariant method of detecting and identifying gases within a scene. The image is evaluated on a pixel-by-pixel basis and is studied at the subpixel level. A library of target gas spectra is generated using a simple slab radiance model. This results in a more robust description of gas spectra which are representative of real-world observations. This library is the subspace utilized by the detection and identification algorithms. The subspace will be evaluated for the set of basis vectors that best span the subspace. The Lee algorithm will be used to determine the set of basis vectors, which implements the Maximum Distance Method (MaxD). A Generalized Likelihood Ratio Test (GLRT) determines whether or not the pixel contains the target. The target can be either a single species or a combination of gases. Synthetically generated scenes will be used for this research. This work evaluates whether the Lee invariant algorithm will be effective in the gas detection and identification problem

    Management transition to the Great Lakes nearshore: Insights from hydrodynamic modeling

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    The emerging shift in Great Lakes management from offshore to nearshore waters will require attention to complexities of coastal hydrodynamics and biogeochemical transformations. Emphasizing hydrodynamics, this work resolves transport processes in quantifying discharge plume and pollutant of concern (POC) footprint dimensions, the latter being the portion of the plume where water quality standards are not met. A generic approach, isolated from pollutant-specific biokinetics, provides first-approximation estimates of the footprint area. A high-resolution, linked hydrodynamic-tracer model is applied at a site in the Greater Toronto Area on Lake Ontario. Model results agree with observed meteorological and hydrodynamic conditions and satisfactorily simulate plume dimensions. Footprints are examined in the context of guidelines for regulatory mixing zone size and attendant loss of beneficial use. We demonstrate that the ratio of the water quality standard to the POC concentration at discharge is a key determinant of footprint dimensions. Footprint size for traditional pollutants (ammonia, total phosphorus) meets regulatory guidelines; however, that for soluble reactive phosphorus, a presently unattended pollutant, is ~1–2 orders of magnitude larger. This suggests that it may be necessary to upgrade treatment technologies to maintain consistency with regulatory guidelines and mitigate manifestations of the eutrophication-related soluble reactive phosphorus POC

    Zika Virus-Specific IgY Results Are Therapeutic Following a Lethal Zika Virus Challenge without Inducing Antibody-Dependent Enhancement

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    The Zika virus (ZIKV) is a newly emerged pathogen in the Western hemisphere. It was declared a global health emergency by the World Health Organization in 2016. There have been 223,477 confirmed cases, including 3720 congenital syndrome cases since 2015. ZIKV infection symptoms range from asymptomatic to Gullain–Barré syndrome and extensive neuropathology in infected fetuses. Passive and active vaccines have been unsuccessful in the protection from or the treatment of flaviviral infections due to antibody-dependent enhancement (ADE). ADE causes an increased viral load due to an increased monocyte opsonization by non-neutralizing, low-avidity antibodies from a previous dengue virus (DENV) infection or from a previous exposure to ZIKV. We have previously demonstrated that polyclonal avian IgY generated against whole-killed DENV-2 ameliorates DENV infection in mice while not inducing ADE. This is likely due to the inability of the Fc portion of IgY to bind to mammalian Fc receptors. We have shown here that ZIKV oligoclonal IgY is able to neutralize the virus in vitro and in IFNAR−/− mice. The concentration of ZIKV-specific IgY yielding 50% neutralization (NT50) was 25 µg/mL. The exposure of the ZIKV, prior to culture with ZIKV-specific IgY or 4G2 flavivirus-enveloped IgG, demonstrated that the ZIKV-specific IgY does not induce ADE. ZIKV IgY was protective in vivo when administered following a lethal ZIKV challenge in 3-week-old IFNAR−/− mice. We propose polyclonal ZIKV-specific IgY may provide a viable passive immunotherapy for a ZIKV infection without inducing ADE
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