The role of GEOSS in monitoring ecosystems and their services

Global declines in biodiversity and ecosystem services have triggered national and international agreements to halt and reverse these trends (e.g. the Convention on Biological Diversity's target of achieving a significant reduction in the current rate of biodiversity loss by 2010). These agreements have highlighted the need for monitoring systems which accurately describe the conditions and trends of biodiversity and ecosystem services, as well as the drivers of change. GEOSS aims to contribute to these needs in the ecosystems and biodiversity benefit areas. We demonstrate the benefits of GEOSS in the monitoring and assessment of biodiversity and ecosystem services using a case study from a semi-arid biodiversity hotspot in South Africa. Using data poor (non-GEOSS) and data rich (GEOSS) scenarios we highlight the substantial differences found in biodiversity and ecosystem service condition. We link these findings to the need for careful and well informed management of ecosystems in semi-arid regions. We conclude with a summary of the costs and benefits of improved data

Continuous Transition between Antiferromagnetic Insulator and Paramagnetic Metal in the Pyrochlore Iridate Eu2Ir2O7

Our single crystal study of the magneto-thermal and transport properties of the pyrochlore iridate Eu2Ir2O7 reveals a continuous phase transition from a paramagnetic metal to an antiferromagnetic insulator for a sample with stoichiometry within ~1% resolution. The insulating phase has strong proximity to an antiferromagnetic semimetal, which is stabilized by several % level of the off-stoichiometry. Our observations suggest that in addition to electronic correlation and spin-orbit coupling the magnetic order is essential for opening the charge gap.Comment: 6 pages, 6 figure

How Newly Acquainted Dyads Develop Shared Stereotypic Impressions through Conversation

This study investigated how feelings of closeness at initial acquaintance encourage the development of shared stereotypic impressions of others through conversation. At least early in a relationship, closer dyads may be especially inclined to get along with one another. In order to satisfy this goal, they should focus their conversations around easily agreed upon stereotypic attributes and spontaneously express agreement about those attributes. As a consequence, the shared impressions that they form should be relatively stereotypic. In this study, closeness was manipulated in previously unacquainted college-age dyads, who then discussed their impressions of an elderly woman. Closer dyads allocated more discussion time to stereotypic attributes, expressed agreement about those attributes, invoked stereotypic exemplars, and ultimately formed more stereotypic shared impressions. The discussion considers study limitations and possible boundary conditions of the effects, as well as implications for the transmission of outgroup stereotypes during socialization to a new ingroup

Hybridization of sub-gap states in one-dimensional superconductor/semiconductor Coulomb islands

We present measurements of one-dimensional superconductor-semiconductor Coulomb islands, fabricated by gate confinement of a two-dimensional InAs heterostructure with an epitaxial Al layer. When tuned via electrostatic side gates to regimes without sub-gap states, Coulomb blockade reveals Cooper-pair mediated transport. When sub-gap states are present, Coulomb peak positions and heights oscillate in a correlated way with magnetic field and gate voltage, as predicted theoretically, with (anti) crossings in (parallel) transverse magnetic field indicating Rashba-type spin-orbit coupling. Overall results are consistent with a picture of overlapping Majorana zero modes in finite wires

Impact of the introduction of a specialist critical care pharmacist on the level of pharmaceutical care provided to the critical care unit

Objectives To evaluate the impact of a dedicated specialist critical care pharmacist service on patient care at a UK critical care unit (CCU). Methods Pharmacist intervention data was collected in two phases. Phase 1 was with the provision of a non-specialist pharmacist chart review service and Phase 2 was after the introduction of a specialist dedicated pharmacy service. Two CCUs with established critical care pharmacist services were used as controls. The impact of pharmacist interventions on optimising drug therapy or preventing harm from medication errors was rated on a 4-point scale. Key findings There was an increase in the mean daily rate of pharmacist interventions after the introduction of the specialist critical care pharmacist (5.45 versus 2.69 per day, P < 0.0005). The critical care pharmacist intervened on more medication errors preventing potential harm and optimised more medications. There was no significant change to intervention rates at the control sites. Across all study sites the majority of pharmacist interventions were graded to have at least moderate impact on patient care. Conclusion The introduction of a specialist critical care pharmacist resulted in an increased rate of pharmacist interventions compared to a non-specialist pharmacist service thus improving the quality of patient care

Quiescence: early evolutionary origins and universality do not imply uniformity

Cell cycle investigations have focused on relentless exponential proliferation of cells, an unsustainable situation in nature. Proliferation of cells, whether microbial or metazoan, is interrupted by periods of quiescence. The vast majority of cells in an adult metazoan lie quiescent. As disruptions in this quiescence are at the foundation of cancer, it will be important for the field to turn its attention to the mechanisms regulating quiescence. While often presented as a single topic, there are multiple forms of quiescence each with complex inputs, some of which are tied to conceptually challenging aspects of metazoan regulation such as size control. In an effort to expose the enormity of the challenge, I describe the differing biological purposes of quiescence, and the coupling of quiescence in metazoans to growth and to the structuring of tissues during development. I emphasize studies in the organism rather than in tissue culture, because these expose the diversity of regulation. While quiescence is likely to be a primitive biological process, it appears that in adapting quiescence to its many distinct biological settings, evolution has diversified it. Consideration of quiescence in different models gives us an overview of this diversity