11 research outputs found
Asymptomatic Bacteriuria and Antibacterial Susceptibility Patterns in an Obstetric Population
Introduction. Asymptomatic bacteriuria (ASB),
occurring in 2–11% of pregnancies, is a major predisposition to
the development of pyelonephritis, which is associated with obstetrical complications,
such as preterm labor and low birth weight infants. The aim of this study was to determine
the prevalence of ASB, the antibacterial susceptibilities of the isolated microorganisms and
the associated risk factors in an outpatient clinical setting in Zekai Tahir Burak Women's
Health Education and Research Hospital in Ankara, Turkey.
Material and Methods. Between December 2009 and May 2010,
pregnant women admitted to the antenatal outpatient clinic were included in this study.
The results of a complete urine analysis, midstream urine culture and antibacterial susceptibility were
evaluated. Results. Of the 2011 pregnant women included, 171 had ASB (8.5%).
E. coli was the most frequently isolated microorganism (76.6%), followed by
Klebsiella pneumonia (14.6%). Both microorganisms were highly sensitive to
fosfomycin, sensivity being 99.2% for E. coli and 88% for Klebsiella pneumonia.
Conclusions. In this certain geographical region, we found E. coli
as the most common causative agent of ASB in the obstetric population and it is very
sensitive to fosfomycin. We recommend fosfomycin for ASB in pregnant women
due to its high sensitivity, ease of administration and safety for use in pregnancy