ESTIMASI HUBUNGAN POROSITAS DAN PERMEABILITAS PADA BATUPASIR (Study kasus FORMASI KEREK, LEDOK,SELOREJO)

The research to know the relation of porosity and permeability on sandstone from Kerek, Ledok, and Selorejo formation is carried out. Permeability is measured using Ruska Gas Permeameter, and the porosity is measured using Helium Porosimeter. The relation between porosity and permeability on sandstone taken by linear regretion method. The result of linear corellation analysis shows that there is a positive relation between porosity and permeability on sandstone samples. Data was processed by using linear regression and the result is log k = 0,06f + 0,34 with r= 0,95. where k in mD and f in percent

OPTIMASI SIMPANG MIROTA KAMPUS SEBAGAI ANTISIPASI RENCANA PENERAPAN SISTEM JALAN SATU ARAH PADA JALAN CORNEL SIMANJUNTAK

In 2014, the Yogyakarta Communication of the Services plans to change the traffic flow in C. Simanjuntak Street from two-way to one-way which will start from the intersection of Mirota Kampus to the south. However, the plan to change the one-way on C.Simanjuntak Street will have an impact on the regulation of traffic signals at the intersection of Mirota Kampus so it needs to be reset as optimal as possible so not to cause congestion at the other intersections, especially the intersection of Pharmacy UGM and UGM roundabout. Primary data collection is done by measuring the geometric conditions, traffic volume survey, saturated flow field, and the queue length field is further processed by MKJI 1997 method to get the level of performance of the intersection. Furthermore, the traffic volume data compared with the prediction of the primary secondary data has been studied by the Traffic Management Study Area of C. Simanjuntak and the surrounding from the Yogyakarta Communication of the Services (2010) when the C. Simanjuntak Street be a one-way street. Comparative analysis was conducted in order to obtain a more predictive approach to the future conditions. Calculation results indicate that the existing condition of the intersection of Mirota Kampus already very saturated because of the degree of saturation at each approach has achieved � 0.85. Reduction in the number of phase with the direct operation of the rules turn left (LTOR) in northern approach is the best anticipation if a one-way system on C. Simanjuntak Street applied. It is shown from the reduced cycle time from 171 seconds to 62 seconds and the degree of saturation at each of approach <0.85. In addition, the intersection delay of 172.03 sec/pcu be only 22.55 sec/pcu so that the level of performance of the intersection after the one-way system applied on C. Simanjuntak Street would be more optimal

Detection of Papua New Guinea Thalassemia Alpha Mutation in Gayo, Sumba, Ternate, and Timika Populations

Abstract &nbsp; Papua New Guinea (PNG) mutation is a point mutation that occurs in noncoding region of alpha globin clusters. Polymorphism promotes an additional recognition site for transcription factor (GATA-1) which presumably downregulates alpha globin synthesis. The aim of this research is to detect PNG mutation in other populations in Indonesia, thus the results will be used for completing standard diagnoses in detecting alpha thalassemia mutation based on ethnic background. The method used in detecting PNG mutation was PCR-RFLP. Detection of 399 samples (MCH &lt;80 fL) using the PCR-RFLP method showed positive results for the Timika population. However, negative results were found in the Gayo, Sumba, and Ternate populations. PNG mutation frequency in the Timika (Papuan ethnic) population is 18.1% (28 of 154 samples). High malaria prevalence in East Indonesia did not show a positive correlation with the absence of PNG mutation in the Sumba and Ternate populations. The results showed that PNG mutation is only found groups that are infected with Plasmodium falciparum malaria, but not in Plasmodium vivax-infected ones. However, PNG mutation is common in the eastern Indonesia population. &nbsp; &nbsp; Abstrak &nbsp; Deteksi Mutasi Papua Nugini (PNG) Thalassemia Alfa di Populasi Gayo, Sumba, Ternate, dan Timika. Mutasi PNG merupakan mutasi titik di luar gugus globin alfa. Polimorfisme menyebabkan terbentuknya promoter baru sebagai situs pengikatan faktor transkripsi GATA-1 yang diduga menurunkan laju transkripsi normal globin alfa. Tujuan dari penelitian ini adalah untuk mengetahui keberadaan mutasi PNG di populasi lain di Indonesia, sehingga hasil penelitian ini dapat digunakan untuk melengkapi standar diagnosis dalam mendeteksi mutasi penyebab thalassemia alfa berdasarkan latar belakang etnik. Teknik yang digunakan dalam mendeteksi mutasi PNG adalah PCR-RFLP. Hasil menunjukkan 18,1% (28 dari 154 sampel) positif pada populasi Timika, namun hasil negatif ditunjukkan pada semua sampel DNA populasi Gayo, Sumba, dan Ternate. Prevalensi malaria yang tinggi di wilayah Indonesia Timur tidak menunjukkan korelasi positif terhadap keberadaan mutasi PNG di populasi Sumba dan Ternate. Hasil penelitian menunjukkan bahwa mutasi PNG ditemukan hanya pada kelompok individu yang terinfeksi Plasmodium falciparum tetapi tidak pada kelompok individu yang terinfeksi Plasmodium vivax dan mutasi PNG juga ditemukan pada satu individu beretnik Ambon yang tinggal di Timika. &nbsp

Detection of Papua New Guinea Thalassemia Alpha Mutation in Gayo, Sumba, Ternate, and Timika Populations

AbstractPapua New Guinea (PNG) mutation is a point mutation that occurs in noncoding region of alpha globin clusters. Polymorphism promotes an additional recognition site for transcription factor (GATA-1) which presumably downregulates alpha globin synthesis. The aim of this research is to detect PNG mutation in other populations in Indonesia, thus the results will be used for completing standard diagnoses in detecting alpha thalassemia mutation based on ethnic background. The method used in detecting PNG mutation was PCR-RFLP. Detection of 399 samples (MCH5 hlm