ON SOME NUMERICAL INTEGRATION CURVES FOR PDE IN NEIGHBORHOOD OF "BUTTERFLY" CATASTROPHE POINT

We consider a three-dimensional nonlinear wave equation with the source term smoothly changing over time and space due to a small parameter. The behavior of solutions of this PDE near the typical “butterfly” catastrophe point is studied. In the framework of matched asymptotic expansions method we derive a nonlinear ODE of the second order depending on three parameters to search for the special solution describing the rapid restructuring of the solution of the PDE in a small neighborhood of the catastrophe point, matching with expansion in a more outer layer. Numerical integration curves of the equation for the leading term of the inner asymptotic expansion are obtained

Economic sovereignty of the Russian Federation under the current conditions

On the basis of cross-industrial approach, the article investigates the features of economic sovereignty of the government, studying its political, legal and economical aspects. Author definitions of economic sovereignty, government sovereignty are provided, as well as argu-ments describing its differences from economic independence and economic security. Article provides characteristics of modern conditions of economic sovereignty that define future ways of development.peer-reviewe

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Urban land use planning within the system of sustainable urban development management

Agricultural and forest lands near settlements are main reserve for expansion of urban areas. Thus, among 148.5 thousand hectares of lands added to Moscow city territory in 2012, 72.2 thousand hectares or 48% were occupied by agricultural and forest lands. Urban areas are characterized by excessively high intensity of land use, land depletion, deterioration in environmental quality and decline in sustainability of urban development. The paper presents the results of analysis of urban land use planning system in the interests of sustainable development of urban territories. The object of the study is the land that is part of Moscow, which is planned to be developed in the coming decades. The authors propose an algorithm for urban development of such areas, which takes into account the quality of land. Design calculations for areas under development were carried out for Shchapovskoye settlement in New Moscow as an example. In addition, the paper covers aspects of land management when developing agricultural land within cities. The authors developed a classification of agricultural land according to a criterion of “suitability for urban development”. The suggested classification has been applied to achieve the objectives of planning urban land use development, determining the order of construction on agricultural lands within the system of sustainable urban development management

Calculation of Durability and Fatigue Life Parameters of Structural Alloys Using a Multilevel Model of Acoustic Emission Pulse Flow

The issues of durability and fatigue life of various structural materials occupy an important place in the operation of equipment and elements subjected to high stresses. To correctly predict its operation time, knowledge of the unique internal structure of a particular piece of operating equipment is required. To obtain such data, a multilevel model of acoustic emission signal flow is proposed in the article, which is based on the kinetic concept of strength and the selection of various stages of destruction in the kinetics of damage accumulation. The selected information, which accounts for the hypothesis of the linear summation of damage, is used in modern models for calculating fatigue life based on kinetic parameters, e.g., the activation energy of destruction and activation volume. The fracture activation energies, activation volume, destructive load, and fatigue life of various structural alloys and steels were calculated using the proposed acoustic emission model based on static test data from various scientific literature sources. For comparison, several methods of calculating kinetic parameters based on the thermal fluctuation concept of strength were used. In addition, numerical modeling was performed to select the structural lethargy coefficient from the elastic deformation zone. The results of the proposed model are in good agreement with the experimental data and allow—within the framework of more thorough tests and with a more accurate consideration of temperature—for the application of an engineering-based approach with which to evaluate the durability and residual service life of objects

Research Journal of Pharmaceutical, Biological and Chemical Sciences Rotary Machines for Production of Ceramic Wall Materials

ABSTRACT This paper deals with an analytical study of design and operating principle of machines for molding plastic materials, using clay as an example. It has been shown that screw press, which has separated transportation and molding functions, can not reduce metal and power consumption of the pressing process. The directions of constructive-technological improvement of machinery for the manufacture of rough ceramics has been determined, in order to reduce the power consumption of the molding process and improve the quality of finished products. There is a design of rotary machines, which combines both transportation and molding functions, and the compression process is near to manual molding process, eliminating streaking in the structure of the clay timber

Mössbauer Synchrotron and X-ray Studies of Ultrathin YFeO3 Films

The YFeO3 orthoferrite is one of the most promising materials for antiferromagnetic (AFM) spintronics. Most studies have dealt with bulk samples, while the thin YFeO3 films possess unusual and variable properties. Ultrathin (3–50 nm) YFeO3 films have been prepared by magnetron sputtering on the r-plane (1 1¯ 0 2)-oriented Al2O3 substrates (r-Al2O3). Their characterization was undertaken by the Mössbauer reflectivity method using a Synchrotron Mössbauer Source and by X-ray diffraction (XRD) including grazing incidence diffraction (GI-XRD). For thin films with different thicknesses, the spin reorientation was detected under the application of the magnetic field of up to 3.5 T. Structural investigations revealed a predominant orthorhombic highly textured YFeO3 phase with (00l) orientation for relatively thick (>10 nm) films. Some inclusions of the Y3Fe5O12 garnet (YIG) phase as well as a small amount of the hexagonal YFeO3 phase were detected in the Mössbauer reflectivity spectra and by XRD

Mössbauer Synchrotron and X-ray Studies of Ultrathin YFeO₃ Films

The YFeO3 orthoferrite is one of the most promising materials for antiferromagnetic (AFM) spintronics. Most studies have dealt with bulk samples, while the thin YFeO3 films possess unusual and variable properties. Ultrathin (3–50 nm) YFeO3 films have been prepared by magnetron sputtering on the r-plane (1 1¯ 0 2)-oriented Al2O3 substrates (r-Al2O3). Their characterization was undertaken by the Mössbauer reflectivity method using a Synchrotron Mössbauer Source and by X-ray diffraction (XRD) including grazing incidence diffraction (GI-XRD). For thin films with different thicknesses, the spin reorientation was detected under the application of the magnetic field of up to 3.5 T. Structural investigations revealed a predominant orthorhombic highly textured YFeO3 phase with (00l) orientation for relatively thick (>10 nm) films. Some inclusions of the Y3Fe5O12 garnet (YIG) phase as well as a small amount of the hexagonal YFeO3 phase were detected in the Mössbauer reflectivity spectra and by XRD