Anxiety and Depression in Adults with Autism Spectrum Disorder: A Systematic Review and Meta-analysis

Adults with autism spectrum disorder (ASD) are thought to be at disproportionate risk of developing mental health comorbidities, with anxiety and depression being considered most prominent amongst these. Yet, no systematic review has been carried out to date to examine rates of both anxiety and depression focusing specifically on adults with ASD. This systematic review and meta-analysis examined the rates of anxiety and depression in adults with ASD and the impact of factors such as assessment methods and presence of comorbid intellectual disability (ID) diagnosis on estimated prevalence rates. Electronic database searches for studies published between January 2000 and September 2017 identified a total of 35 studies, including 30 studies measuring anxiety (n = 26 070; mean age = 30.9, s.d. = 6.2 years) and 29 studies measuring depression (n = 26 117; mean age = 31.1, s.d. = 6.8 years). The pooled estimation of current and lifetime prevalence for adults with ASD were 27% and 42% for any anxiety disorder, and 23% and 37% for depressive disorder. Further analyses revealed that the use of questionnaire measures and the presence of ID may significantly influence estimates of prevalence. The current literature suffers from a high degree of heterogeneity in study method and an overreliance on clinical samples. These results highlight the importance of community-based studies and the identification and inclusion of well-characterized samples to reduce heterogeneity and bias in estimates of prevalence for comorbidity in adults with ASD and other populations with complex psychiatric presentations

HIGH DENSITY SLAG CONCRETE

Test results are presented that show that a strong concrete weighing approximately 185 lb/ft/sup 3/ can be made using water, waste lead slag, and Ciment Fondu. Feasibility, materials, mortar tests, concrete tests, and Ciment Fondu concretes are discussed. A 24-in.-thick concrete shield wall would have to be increased in thickness by 5 in. if slag concrete is used in place of barytes or magnetite concrete. On a pound-for-pound basis, the waste lead slag concrete materials were 30% cheaper than barytes and magnetite concrete materials. (M.C.G.

HTGR analytical methods and design verification

Analytical methods for the high-temperature gas-cooled reactor (HTGR) include development, update, verification, documentation, and maintenance of all computer codes for HTGR design and analysis. This paper presents selected nuclear, structural mechanics, seismic, and systems analytical methods related to the HTGR core. This paper also reviews design verification tests in the reactor core, reactor internals, steam generator, and thermal barrier

Entanglement of trapped-ion qubits separated by 230 meters

We report on an elementary quantum network of two atomic ions separated by 230 m. The ions are trapped in different buildings and connected with 520(2) m of optical fiber. At each network node, the electronic state of an ion is entangled with the polarization state of a single cavity photon; subsequent to interference of the photons at a beamsplitter, photon detection heralds entanglement between the two ions. Fidelities of up to $(88.2+2.3-6.0)\%$ are achieved with respect to a maximally entangled Bell state, with a success probability of $4 \times 10^{-5}$. We analyze the routes to improve these metrics, paving the way for long-distance networks of entangled quantum processors

Entanglement of trapped-ion qubits separated by 230 meters

International audienceWe report on an elementary quantum network of two atomic ions separated by 230 m. The ions are trapped in different buildings and connected with 520(2) m of optical fiber. At each network node, the electronic state of an ion is entangled with the polarization state of a single cavity photon; subsequent to interference of the photons at a beamsplitter, photon detection heralds entanglement between the two ions. Fidelities of up to $(88.2+2.3-6.0)\%$ are achieved with respect to a maximally entangled Bell state, with a success probability of $4 \times 10^{-5}$. We analyze the routes to improve these metrics, paving the way for long-distance networks of entangled quantum processors

Entanglement of trapped-ion qubits separated by 230 meters

We report on an elementary quantum network of two atomic ions separated by 230 m. The ions are trapped in different buildings and connected with 520(2) m of optical fiber. At each network node, the electronic state of an ion is entangled with the polarization state of a single cavity photon; subsequent to interference of the photons at a beamsplitter, photon detection heralds entanglement between the two ions. Fidelities of up to $(88.2+2.3-6.0)\%$ are achieved with respect to a maximally entangled Bell state, with a success probability of $4 \times 10^{-5}$. We analyze the routes to improve these metrics, paving the way for long-distance networks of entangled quantum processors