Mental Health of People Who Are Going to Marry and Its Relation to Some of Their Demographic Factors

Introduction: Marriage is one of the most important events during an individual's life. Mental health as a component of personal characteristics, are associated with marital satisfaction. considering the role of mental health in a successful marriage, the impact of family health on community mental health, and major role of couples in this regard the present study aimed to determine the Mental health of people who are going to marry and its relation to some of their demographic factors in karaj 2012. Material and Methods: We performed a cross sectional study on the established group of 600 people who attended premarital assessment in a health center. They were selected by convenient sampling method. The data collection instrument was a demographic questionnaire and standardized Goldberge mental health (GHQ-28) questionnaire. The data was analyzed with SPSS/18 using descriptive and inferential statistical methods.(P<0.05) Findings: The mean score of mental health questionnaire was (16/2 &plusmn; 9/9). The results also showed that mental health and sex, religion, place of birth, marital history and employment status were significantly related (P<0.05) such that the mental health of men, Shea, born in the village, no history of marriage, and have a permanent job was higher. Conclusion: Recent research results indicate the desirability of mental health in 80.3 percent of in new couples

Effect of Helicobacter pylori on metabolic syndrome parameters in diabetic patients

Aim: The aim of this study is to survey the effect of Helicobacter Pylori on metabolic syndrome parameters in diabetic patients. Background: Helicobacter pylori (HP) infection is the most common infection in developing countries. Some studies showed the association between HP infection and insulin resistance. Insulin resistance is a major mechanism in the development of metabolic syndrome (MetS) and it is said that MetS is more prevalent among HP infected subjects. Also, some studies have shown that MetS is common among patients with type 2 diabetes mellitus. In this study, we aimed to investigate the prevalence of MetS in diabetic patients and its association with HP. Methods: This cross-sectional study was carried out from May to December 2014 on 211 diabetic patients. For each patient, the following data were collected: age, gender, diabetes duration, weight, body mass index (BMI), waist circumference, blood pressure (BP), HDL, cholesterol, triglyceride (TG), total cholesterol, and HbA1c. The lipid profile was performed on fasting samples. Anti- HP IgG antibody was measured and serum titer > 30AU/mL was considered positive. MetS was diagnosed by The National Cholesterol Education Program's Adult Treatment Panel III report (NCEP-ATPIII) and IDF criteria. Results: Totally 139 patients (65.9) were HP+ and 72 patients (34.1) were HP-. Age, gender and diabetes duration were not significantly different in both groups. BMI was significantly lower in HP+ women (29.05�5.26 vs. 31.45�4.8, p = 0.02). Although the waist circumference of men was not different between the two groups but it was significantly lower in HP+ women (102.04�12.37 vs. 97.3�10, p = 0.03). Although BP and TG levels were not statistically different in HP+ and HP- patients, but HP+ patients had lower HDL level (p = 0.037) which was due to lower HDL in men (58.2�26.6 vs. 72.48�28.1, p = 0.012). The prevalence of MetS according to the IDF criteria among HP+ and HP- patients was 76.6 vs. 69.8 (p = 0.27). Also, the prevalence of MetS according to NCEP-ATP III criteria among HP+ and HP- patients was 90.4 vs. 87.2 (p = 0.5). Duration of diabetes did not affect the prevalence of metabolic syndrome among HP+ and HP- patients. Conclusion: It seems that HP infection increases the prevalence of metabolic syndrome through an increase in insulin resistance. According to NCEP-ATPIII criteria, the increase in the prevalence of metabolic syndrome in HP+ patients is almost significant, however more complete studies is recommended to investigate this relationship. � 2016 RIGLD, Research Institute for Gastroenterology and Liver Diseases

Survey of Anxiety Levels and Its Relation to Students Demographic of Alborz University of Medical Sciences

Background: Today, changing lifestyles, social relations and the advancement of technology causes fear, threats and concerns of different groups in society, especially students. Adverse impact of Anxiety on the efficacy and talents, personality and social identity formation of students, threat to achieve the goals of academic achievement and mental health. The present study was conducted to determine level of anxiety and some of their demographic correlates in the Alborz University of Medical Sciences in 1390. Methods: This study is a descriptive cross sectional study. The study population included all students of the Alborz university. 305 students were selected by stratified random sampling method. The data collection instrument was a demographic questionnaire and standardized Spielberger Anxiety Inventory. Data were analyzed using descriptive and inferential statistical methods. Results: Based on our results, 64 percent of students were anxious. Anxiety levels were significantly higher in men than women (p=0.049). The level of anxiety and interesting in medical course (p<0.001), non-academic study (p=0.007) and a major physical illness (p=0.009) had significant correlations with together. Conclusion: Results showed a high percentage of students anxious. Regarding the relation between anxiety and other problems such as depression and other disorders including failure in educational function, social relationships and lifestyle, Training courses on coping skills for anxiety and stress as well as consulting services and further guidance is recommended for them

Evaluation of involved proteins in colon adenocarcinoma: an interactome analysis

Aim: Assessment of related genes to colon cancer to introduce crucial ones, was the aim of this research. Background: Colon cancer is one of the invasive colorectal diseases. This disease is preventable and manageable if it be diagnosed in early stage. The aggressive tools for its detection imply more investigation for new molecular diagnostic methods. Methods: Numbers of 300 genes from String database (SD) are analyzed via constructed Protein-protein interaction (PPI) network by Cytoscape software 3.4.0. Based on centrality parameters the main connected component of network was analyzed and the crucial genes were introduced. Cluster analysis of the network and gene ontology for the nodes of the main cluster revealed more details about the role of the key proteins related to colon cancer disease. Results: The constructed network was consisted of 300 genes which among them 68 genes were isolated and the 232 other genes formed the main connected component. Ten crucial genes related to colon adenocarcinoma were introduced that presented in cluster 1. Gene ontology analysis showed that cluster 1 is involved in 226 biological processes which are classified in 25 groups. Conclusion: In conclusion, results indicate that the identified key proteins play significant roles in colon adenocarcinoma. It may be possible to introduce a few diagnostic biomarker candidates for colon cancer disease

The diagnosis and management of a patient with acute pyelonephritis

Lower urinary tract infections account for more than 224 000 hospital admissions each year and nearly all of these have the pathophysiological possibility to develop into pyelonephritis, known clinically as an upper urinary tract infection. Acute pyelonephritis is characterised by inflammation of the renal parenchyma caused by bacteriuria ascending from the bladder, up the ureters to the kidneys. Effective history taking, combined with refined physical examination skills, are the two most powerful tools to differentiate upper and lower urinary tract infections as well as assisting the practitioner to exclude other differential diagnoses. Utilisation of these skills by the practitioner, together with the recognised presenting symptom triad of flank pain, fever and nausea in this case study, enabled the diagnosis of acute pyelonephritis to be given.N/