Survey of lungworm infection of domestic cats in Hungary

From 61 settlements of 12 Hungarian counties, 303 domestic cats were included in this survey. Between autumn 2016 and spring 2018, fresh faecal samples were randomly collected and examined by flotation and by the Baermann–Wetzel method for the presence of lungworm infection. No eggs of Eucoleus aerophilus were detected. Morphological identification of first instar larvae (L1) was also carried out. In the faeces of 60 cats (19.8%) from 17 settlements and Budapest, L1 of Aelurostrongylus abstrusus were found. More than half of the cats were from the western part of the country. The average number of larvae per gram of faeces was 190.2 ± 304.88. These results are in line with the former findings on the prevalence of aelurostrongylosis of domestic cats in Hungary. In addition, Oslerus rostratus was also found for the first time in the faecal samples of three cats from the eastern part of the country, infected also with Ae. abstrusus. The average age (2.51 ± 1.26 years) of infected cats indicates that lungworm infection is more common among younger cats. No relationship was found between the lung-worm infection and the sex of cats. Non-neutered cats had a significantly higher proportion of lungworm infections. Two-thirds of the infected cats were apparently healthy, and only 19 individuals showed clinical signs of respiratory disorders

Egyetemi és fõiskolai hallgatók vállalkozói aktivitása Magyarországon

A fenntartható gazdasági fejlõdés szempontjából különösen fontos az új vállalkozások alapítása. Az új vállalkozások egy részét fiatalok, egyetemisták és fõiskolások alapítják. Ezért is szinte magától értetõdõ annak vizsgálata, hogy a hallgatók közül kik, milyen körülmények között hoznak létre saját vállalkozást. Magyarország 2006-ban kapcsolódott be abba a nemzetközi kutatásba, amely az egyetemisták és fõiskolások vállalkozói készségét és aktivitását értékeli. 2008-ban újabb kérdõíves vizsgálatra került sor a GUESSS projekt keretében. Ebben a tanulmányban a 2008-as kérdõívek feldolgozása alapján foglaljuk össze a nemzetközi tendenciákat és elemezzük a magyar helyzetet. A felsõoktatás hallgatói vállalkozási aktivitásának méréséhez nem elegendõ a hallgatói motiváció értékelése. Az egyetemek-fõiskolák vállalkozói kurzusai és szolgáltatásai fontos szerepet játszanak, ezért egy új mutatót fejlesztettünk, amit egyesítettünk a már korábban is számított hallgatói vállalkozói indexszel, ezt neveztük el felsõoktatási vállalkozói indexnek. (A kutatás az OTKA NK 69283 kutatási program pénzügyi támogatásával valósult meg, köszönet érte.)hallgatói vállalkozói motiváció és aktivitás, hallgatói vállalkozói index, felsõoktatási vállalkozói index

A desedai Községi-erdő talajlakó pókfajainak vizsgálata (Aranea)

In 2011, an aracnological investigation was carried out in Községi erdő near the Deseda lake, local Nature Conservation Area, SW Hungary. The material was recorded by pitfall traps in 13 different habitats. Altogether 5410 specimens were collected. Five species were very abundant (40,77%), namely Allagelena gracilens, Dysdera ninnii, Haplodrassus silvestris, Ozyptila praticola, Trochosa terricola. They annual activities and habitat preferences were also examined with 10 figures

CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats

Successful curative treatment of severe pulmonary arterial hypertension with luminal obliteration will require a thorough understanding of the mechanism underlying the development and progression of pulmonary vascular lesions. But the cells that obliterate the pulmonary arterial lumen in severe pulmonary arterial hypertension are incompletely characterized. The goal of our study was to evaluate whether inhibition of CXC chemokine receptor 4 will prevent the accumulation of c-kit+ cells and severe pulmonary arterial hypertension. We detected c-kit+­ cells expressing endothelial (von Willebrand Factor) or smooth muscle cell/myofibroblast (α-smooth muscle actin) markers in pulmonary arterial lesions of SU5416/chronic hypoxia rats. We found increased expression of CXC chemokine ligand 12 in the lung tissue of SU5416/chronic hypoxia rats. In our prevention study, AMD3100, an inhibitor of the CXC chemokine ligand 12 receptor, CXC chemokine receptor 4, only moderately decreased pulmonary arterial obliteration and pulmonary hypertension in SU5416/chronic hypoxia animals. AMD3100 treatment reduced the number of proliferating c-kit+ α-smooth muscle actin+ cells and pulmonary arterial muscularization and did not affect c-kit+ von Willebrand Factor+ cell numbers. Both c-kit+ cell types expressed CXC chemokine receptor 4. In conclusion, our data demonstrate that in the SU5416/chronic hypoxia model of severe pulmonary hypertension, the CXC chemokine receptor 4-expressing c-kit+ α-smooth muscle actin+ cells contribute to pulmonary arterial muscularization. In contrast, vascular lumen obliteration by c-kit+ von Willebrand Factor+ cells is largely independent of CXC chemokine receptor 4

Differential Gene Expression in Gonadotropin-Releasing Hormone Neurons of Male and Metestrous Female Mice.

BACKGROUND: Gonadotropin-releasing hormone (GnRH) neurons play a pivotal role in regulation of the hypothalamic-pituitary gonadal axis in a sex-specific manner. We hypothesized that the differences seen in reproductive functions of males and females are associated with a sexually dimorphic gene expression profile of GnRH neurons. METHODS AND RESULTS: We compared the transcriptome of GnRH neurons obtained from intact, metestrous female and male GnRH-GFP transgenic mice. About 1,500 individual GnRH neurons from each sex were sampled with laser capture microdissection followed by whole transcriptome amplification for gene expression profiling. Under stringent selection criteria (fold change >1.6, adjusted p value 0.01), Affymetrix Mouse Genome 430 PM array analysis identified 543 differentially expressed genes. Sexual dimorphism was most apparent in gene clusters associated with synaptic communication, signal transduction, cell adhesion, vesicular transport and cell metabolism. To validate microarray results, 57 genes were selected and 91% of their differential expression was confirmed by real-time PCR. Similarly, 88% of microarray results were confirmed with PCR from independent samples obtained by patch pipette harvesting and pooling of 30 GnRH neurons from each sex. We found significant differences in expression of genes involved in vesicle priming and docking (Syt1, Cplx1), GABAergic (Gabra3, Gabrb3, Gabrg2) and glutamatergic (Gria1, Grin1, Slc17a6) neurotransmission, peptide signaling (Sstr3, Npr2, Cxcr4) and the regulation of intracellular ion homeostasis (Cacna1, Cacnb1, Cacng5, Kcnq2, Kcnc1). CONCLUSION: The striking sexual dimorphism of the GnRH neuron transcriptome we report here contributes to the better understanding the differences in cellular mechanisms of GnRH neurons in the two sexes. (c) 2015 S. Karger AG, Basel

Spontaneous emission of radiation by metallic electrons in the presence of electromagnetic fields of surface plasmon oscillations

The spontaneous emission of radiation of metallic electrons embedded in a high-intensity enhanced surface plasmon field is considered analytically. The electrons are described by exact dressed quantum states which contain the interaction with the plasmon field non-perturbatively. Considerable deviations from the pertubative behaviour have been found in the intensity dependence of the emitted fundamental and the second harmonic signals, even at moderate incoming laser intensities. The theoretical predictions deduced from the formalism are in good qualitative agreement with the experimental results.Comment: 23 pages, 6 figure

A felsőoktatási innováció, mint a regionális gazdaság potenciális motorja Pécs példáján

The RDI as a modern and dynamically developing sector of the economy plays a more and more significant role nowdays. Beside the companies and the governmental sphere the higher education institutions are also reliable for the efficiency of the quaternary sector. The article deals with this topic from the aspect of the University of Pécs (UP) as one of the main institute responsible for the innovational activity of the South Transdanubian region and the biggest employer of the city of Pécs. In the course of this after finding the place of Hungary and the region in the EU and in the country as measuring its RDI potential, it examines the external and internal RDI milieu of the UP with a SWOT analysis. After this it reveals the innovational researches of each faculty and the main profile of the spin-off and start-up enterprises connected to them among with their RDI tendering operation between 2007 and 2013. Among others it also deals with the well-known RDI investments of Pécs according to the city’s population and the innovation management process of the UP