The Epidermiology of Hairstyle related african hair disdorders, in and Urban Township in South Africa

The hair of indigenous people of Africa varies from the north to the south of the continent. Although the variation in hair colour from light brown to black occurs, the most significant difference is in the curls which are tightest, and spiral, in indigenous sub Saharan Africans. African hair for the purpose of this thesis refers to the latter hair phenotype. The unique morphology of this hair type is associated with specific responses to grooming. In addition hairstyle preferences may be influenced by politics and fashion. Specific scalp disorders have been anecdotally reported to be more prevalent in Africans. These are acne (folliculitis) keloidalis (AKN), central centrifugal cicatricial alopecia (CCCA) and traction alopecia (TA). For many years all these conditions have been suspected to have a causal association with hairstyles. However, preliminary investigation suggested a lack of population studies demonstrating the latter association. In addition the possible influence of the unique African hair follicle on disease pathogenesis had not been determined. The aims of this thesis were to: Present a systematic 1. literature review of published prevalence and incidence data on the above three conditions. 2. Conduct cross sectional studies to investigate the prevalence of AKN, CCCA and TA in a population of school children and adults and the prevalence of different hairstyles, and to describe any associations between hairstyles and disease. 3. Develop and test for reliability a new severity scoring system for TA the commonest of the above conditions [the marginal traction alopecia severity (M-TAS) scoring instrument]. 4. Evaluate the determinants of both TA presence and severity in African females using data from our cross sectional studies in school children and adults

Health risks of the clean-shave chiskop haircut

The clean-shave haircut known locally as the chiskop is rare among females but popular with black South African men, who are also predisposed to folliculitis keloidalis nuchae (FKN) (keloids on the back of the head). During a previous study, participants described an unexpected symptom of haircut-associated bleeding. As this is not a widely recognised entity, we conducted the present study at an HIV clinic servicing the same population, with the objective of comparing the prevalences of haircut-associated bleeding and FKN in 390 HIV-positive subjects with published data for Langa (Western Cape, South Africa). The results for HIV-positive participants were similar to the population data, but in both groups the prevalence of haircut-associated bleeding (24.5% v. 32%; p =0.17) was much higher than that of FKN (10.2% v. 10.5%), suggesting that the hairstyle increases the risk of bleeding even in people with healthy scalps without folliculitis. This study does not (and was not intended to) prove a higher HIV prevalence in chiskop wearers or in FKN sufferers, but it confirms a history of haircut-associated bleeding in at least a quarter of our male study participants. The risk of transmission of blood-borne infection via haircuts is likely to be low, but requires formal quantification. Public education on adequate sterilisation of barber equipment between haircuts and promotion of individual hair-clipper ownership for chiskop clients should not be delayed. Depilatory creams formulated for African hair offer a non-mechanical means of achieving clean-shave hairstyles

Health risks of the clean-shave chiskop haircut

The clean-shave haircut known locally as the chiskop is rare among females but popular with black South African men, who are also predisposed to folliculitis keloidalis nuchae (FKN) (keloids on the back of the head). During a previous study, participants described an unexpected symptom of haircut-associated bleeding. As this is not a widely recognised entity, we conducted the present study at an HIV clinic servicing the same population, with the objective of comparing the prevalences of haircut-associated bleeding and FKN in 390 HIV-positive subjects with published data for Langa (Western Cape, South Africa). The results for HIV-positive participants were similar to the population data, but in both groups the prevalence of haircut-associated bleeding (24.5% v. 32%; p=0.17) was much higher than that of FKN (10.2% v. 10.5%), suggesting that the hairstyle increases the risk of bleeding even in people with healthy scalps without folliculitis. This study does not (and was not intended to) prove a higher HIV prevalence in chiskop wearers or in FKN sufferers, but it confirms a history of haircut-associated bleeding in at least a quarter of our male study participants. The risk of transmission of blood-borne infection via haircuts is likely to be low, but requires formal quantification. Public education on adequate sterilisation of barber equipment between haircuts and promotion of individual hair-clipper ownership for chiskop clients should not be delayed. Depilatory creams formulated for African hair offer a non-mechanical means of achieving clean-shave hairstyles

“Next generation sequencing identifies mutations in GNPTG gene as a cause of familial form of scleroderma-like disease”

A letter to the editor making some recommendations on the article entitled “Next generation sequencing identifies mutations in GNPTG gene as a cause of familial form of scleroderma-like disease”

Systems Approach to Human Hair Fibers: Interdependence Between Physical, Mechanical, Biochemical and Geometric Properties of Natural Healthy Hair

Contextual interpretation of hair fiber data is often blind to the effects of the dynamic complexity between different fiber properties. This intrinsic complexity requires systems thinking to decipher hair fiber accurately. Hair research, studied by various disciplines, follows a reductionist research approach, where elements of interest are studied from a local context with a certain amount of detachment from other elements or contexts. Following a systems approach, the authors are currently developing a cross-disciplinary taxonomy to provide a holistic view of fiber constituents and their interactions within large-scale dynamics. Based on the development process, this paper presents a review that explores the associated features, interrelationships and interactive complexities between physical, mechanical, biochemical and geometric features of natural, healthy hair fibers. Through the review, the importance of an appropriate taxonomy for interpreting hair fiber data across different disciplines is revealed. The review also demonstrates how seemingly unrelated fiber constituents are indeed interdependent and that these interdependencies may affect the behavior of the fiber. Finally, the review highlights how a non-integrative approach may have a negative impact on the reliability of hair data interpretation