覚醒状態アカゲザルにおける2-[18F]フルオロ-2-デオキシ-D-グルコースの卜レーサー速度論的定数と水の血液-脳組織分配定数の測定および老化・麻酔による変化の解剖学的標準化法を用いたパラメトリック画像での検討

取得学位 : 博士（医学）, 学位授与番号 : 医博甲第1613号, 学位授与年月日 : 平成16年3月25日, 学位授与大学 : 金沢大

Decomposing the Spectrum of Ultra-Luminous X-ray Pulsar NGC 300 ULX-1

A phase-resolved analysis on the X-ray spectrum of Ultra-Luminous X-ray Pulsar (ULXP) NGC 300 ULX-1 is performed with data taken with XMM-Newton and NuSTAR on 2016 December 16th. In addition to the classical phase-restricting analysis, a method developed in active galactic nuclei studies is newly employed for ULXP. It has revealed that the pulsation cycle of the source can be divided into two intervals in terms of X-ray variability. This suggests the rotating flow consists of at least two representative emission regions. Furthermore, the new method successfully decomposed the spectrum into an independent pair in each interval. One is an unchanging-component spectrum that can be reproduced by a standard disk model with a $720^{+220}_{-120}$ km inner radius and a $0.25\pm0.03$ keV peak temperature. The other is the spectrum of the component that coincides with the pulsation. This was explained with a Comptonization of a $0.22^{+0.2}_{-0.1}$ keV blackbody and exhibited a harder photon index in the brighter phase interval of two. The results are consistent with a picture that the pulsating emission originates from a funnel-like flow formed within the magnetosphere, and the inner flow exhibiting a harder continuum is observed exclusively when the opening cone points to the observer.Comment: 27 pages, 15 figures, accepted for publication in Ap

New herpetofaunal records from Gunung Mulu National Park and its surrounding areas in Borneo

Gunung Mulu National Park (GMNP) in northwestern Borneo is marked by high species diversity and diverse environments. We present one new amphibian and ten new reptile records from GMNP and its surrounding area. In the records, Asthenodipsas jamilinaisi and Garthius chaseni were newly recorded in the Sarawak State. We also present the first record of Cyrtodactylus muluensis from outside of GMNP and the second record of Opisthotropis typica from the park. Combined with previous information, a total of 108 amphibians and 104 reptiles are known from GMNP, and their preferred habitat types are diverse. Furthermore, observed male-male combat of Dopasia buettikoferi is the first detailed description of the genus. Two color morphs of D. buettikoferi had an identical ND2 haplotype and appeared to be the same species. The present study provides new information about Bornean amphibians and reptiles, and also emphasizes the importance of continuous monitoring

Longitudinal observation of insulin secretory ability before and after the onset of immune checkpoint inhibitor-induced diabetes mellitus: A report of two cases

Immune checkpoint inhibitor-induced diabetes mellitus is a rare immune-related adverse event. This report illustrates clinical data and insulin secretory ability before and after the onset of immune checkpoint inhibitor-induced diabetes