New Methods Of Locating Business Partners For Joint Development In Japan

This article examines new methods for locating business partners for joint development of manufactured products in Japan.These methods, collectively called the Osaka Model, enable a company with outstanding technology capabilities to partner with a company that needs those capabilities. This paper also discusses what kind of environment should be created for encouraging the use of the model. A large network should be formed where the model is implemented, when successful, the relationship itself is a source of competitiveness of the area

The Influence of Offshore Development on Strategies for Developing China\u27s Software Industry

This article recommends strategies to develop China\u27s software industry, based on our analysis of the recent technology transfer to Chinese software firms from Japan. Li and Gao (2003) recommended that the Chinese software industry focus on its domestic software service market. However, since the end of the 1990s, Chinese software firms have obtained a significant amount of technology contract work from Japan, including coding, testing, and design. Chinese firms have been increasing their design skills through this joint software development with Japan. As a result, offshore software development from Japan has helped Chinese software firms acquire advanced technology. We conclude that the Chinese software industry should focus on both its domestic software service market and the export of software services

Characterization of zebrafish Rad52 and replication protein A for oligonucleotide-mediated mutagenesis

Zebrafish has become a favorite model organism not only in genetics and developmental biology, but also for the study of cancer, neuroscience and metabolism. However, strategies for reverse genetics in zebrafish are mostly limited to the use of antisense oligonucleotides, and therefore the development of other targeting methods is highly desirable. Here, we report an approach to gene targeting in this system in which single-stranded oligonucleotides and zebrafish Rad52 protein are employed. It has been proposed that a single-stranded oligonucleotide containing a mutation can be incorporated into the genome by annealing to the single-stranded region of the lagging strand of the replication fork. Rad52 is expected to accelerate the annealing step. In vitro experiments using purified truncated Rad52 proteins and replication protein A (RPA) showed that annealing of oligonucleotides is accelerated by Rad52 in the presence of RPA. We developed a simple and sensitive PCR-based method to detect point mutations in the genome. In exploratory experiments, we found that microinjection of single-stranded oligonucleotide targeted to a specific gene together with truncated Rad52 into zebrafish embryos resulted in a low level of recombinant copies in 3 of the 80 embryos tested under these conditions

Scaling of soaring seabirds and its implication for the maximum size of flying pterosaurs

The flight ability of animals is restricted by the scaling effects imposed by physical and physiological factors. In comparisons of the power available from muscle and the mechanical power required to fly, theoretical studies have predicted that the margin between the powers should decrease with body size and that flying animals have a maximum body size. However, predicting an absolute value of this upper limit has been difficult because wing morphology and flight styles vary among species. Albatrosses and petrels have long, narrow, aerodynamically efficient wings and are considered to be soaring birds. Here, using animal-borne accelerometers, we show that scaling analyses of wing-flapping frequencies in these seabirds indicate that the maximum size limit for soaring animals is a body mass of 41 kg and a wingspan of 5.1 m. Soaring seabirds were observed to have two modes of flapping frequencies: vigorous flapping during takeoff and sporadic flapping during cruising flight. In these species, high and low flapping frequencies were found to scale with body mass (_mass_ ^-0.30^ and _mass_ ^-0.18^) in a manner similar to the predictions from biomechanical flight models (_mass_ ^-1/3^ and _mass_ ^-1/6^). The scaling relationships predicted that animals larger than the limit will not be able to flap fast enough to stay aloft under unfavourable wind conditions. Our result therefore casts doubt on the flying ability of large, extinct pterosaurs. The largest extant soarer, the wandering albatross, weighs about 10 kg, which might be a pragmatic limit to maintain a safety margin for sustainable flight and to survive in a variable environment

Offshoring of software development from Japan to China / Nobuhiro Takahashi and Mita Li

This article discusses the recent development of offshoring in the software industry in Japan. Following interviews with several Japanese ICT companies, we reveal the present status and problems of offshoring software development, which cannot be recognized from its macro data. Japanese firms must expand offshoring because of increasing competition within Japan, although offshoring creates an outflow of technology and know-how to foreign firms. This outflow fosters prospective foreign competitors, and improves their technology,especially in China. Small and medium-sized Japanese software companies that lack advanced technology will face competition for survival against foreign firms in the near future. The income gap among Japanese software engineers will also increase

Associations of Autism Spectrum Quotient and Personality Profiles with Eating Behaviors in Patients with Anorexia Nervosa and in a Non-clinical Population

Article信州医学雑誌 67(3): 157-166(2019)journal articl

Ion current density profile of laser ablation plasma transported in multicusp magnetic field

Laser ion sources are capable of supplying ion beams with high current because a laser produced plasma has initially high number density same as that of solid. [1]..