Evolução da obesidade da infância até a vida adulta entre mulheres da fila de espera para a cirurgia bariátrica pelo sistema único de saúde

Apesar de muito estudada, a obesidade continua um tema que requer ainda muitos estudos. Ao classificá-la entre os distúrbios psicossomáticos, abre-se um vasto campo de exploração no sentido de entendê-la como um problema de saúde pública fortemente influenciado pelo meio e pela forma com que o sujeito interage com seu ambiente. O objetivo do trabalho foi caracterizar, a partir de relatos sobre a alimentação, os hábitos de vida, a idade de início e a evolução da obesidade entre mulheres adultas da fila de espera para o tratamento cirúrgico da obesidade pelo Sistema Único de Saúde. Participaram do estudo 35 mulheres com idade média de 39,511,7, variando de 21 a 67 anos, e índice de massa corporal (IMC, em Kg/m2) entre 36,1 e 60,1 kg ∕ m2, recrutadas na Clínica Bariátrica de Piracicaba – SP. Para efeito de análise, as mulheres foram agrupadas segundo o período de início da obesidade: 0 ┤10 anos, 10 ┤20 anos, 20 ┤30 anos e >30 anos. O perfil das candidatas, em termos de massa corporal, tempo de espera na fila para a cirurgia bariátrica, informações pessoais, prevalência de comorbidezes, limitações físicas para execução de tarefas da vida diária, bem como as razões para a procura da cirurgia, foram obtidos a partir de um formulário. A história de vida relativa à alimentação, a atividades físicas e de lazer e a tratamentos realizados para perda ponderal foi levantada com auxílio de instrumento de avaliação cronológica dos eventos, “Linha do tempo”, criado para esse fim. A estimativa e a avaliação da adequação do consumo alimentar atual foram realizadas a partir dos dados obtidos em três recordatórios de 24 horas (R24h). Quanto às experiências de vida, não foram percebidas diferenças marcantes entre as mulheres, quando confrontadas conforme o período de início da obesidade. O ambiente obesogênico...Even though obesity has been extensively studied, it is a theme that still requires extensive investigation. Once it became classified as a psychosomatic disorder, a broad field opened up for exploration, i.e., understanding that obesity is a public health problem that is strongly influenced by the environment and by the way individuals interact with the environment. This study used feeding reports to characterize the life habits, age of onset and progression of obesity in adult women recruited from the waiting list for surgical treatment of obesity of the Unified Health System. The participants included 35 women 39.511.7 mean of age, varying from 21 to 67 years, with a body mass index (BMI in kg/m2) of 36.1 to 60.1 kg/m2 seen at the Bariatric Clinic of Piracicaba, SP. Analysis was performed by grouping the women according to the age of onset of obesity: 0 ┤10 years, 10 ┤20 years, 20 ┤30 years and >30 years. A self-administered questionnaire was used to determine the profile of the participants in terms of body mass, time in the waiting list for bariatric surgery, personal information, prevalence of comorbidities, physical limitations that interfere with daily tasks and activities and reasons for seeking surgery. Their life story regarding feeding habits, physical and leisure activities and weight loss treatments was determined with an instrument that assesses the chronological order of events, “Time Line,” created for this purpose. Data obtained from three 24-hour recalls (24HR) were used to estimate and verify the adequacy of actual food intake. Regarding life experiences, there were no marking differences among the women at the onset of obesity. Today’s obesogenic environment, product of this new century, was the habitat of every one of those women from childhood, with its effects being manifested especially in adult life. These women sought surgical treatment in 2005... (Complete abstract click electronic access below)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES

Association of 5-HT2C (rs3813929) and UCP3 (rs1800849) gene polymorphisms with type 2 diabetes in obese women candidates for bariatric surgery

ABSTRACT Objective Obesity can cause systemic arterial hypertension (SAH) and type 2 diabetes mellitus (DM2) factor that is also influenced by genetic variability. The present study aims to investigate the association between gene polymorphisms related with obesity on the prevalence of SAH and DM2 in the preoperative period and 1 year after Roux-en-Y gastric bypass surgery. Subjects and methods In total, 351 obese women in a Brazilian cohort completed the study. The clinical diagnosis of SAH and DM2 was monitored from medical records. Twelve gene polymorphisms (rs26802; rs572169; rs7799039; rs1137101; rs3813929; rs659366; rs660339; rs1800849; rs7498665; rs35874116; rs9701796; and rs9939609) were determined using real-time polymerase chain reaction and TaqMan assay. Results In the preoperative period, prevalence of SAH and DM2 was 57% and 22%, respectively. One year postoperatively, 86.8% subjects had remission of DM2 and 99.5% had control of SAH. Subjects with T allele from the serotonin receptor gene (5-HT2C, rs3813929) had five times greater chance of DM2, and the CC genotype from uncoupling protein 3 gene (UCP3, rs1800849) had three times greater chance in the preoperative period. Conclusion These findings indicate that polymorphisms rs3813929 and rs1800849 from 5-HT2C and UCP3 genes were related to DM2 prevalence among the Brazilian obese women candidates for bariatric surgery

The under-reporting of energy intake influences the dietary pattern reported by obese women in the waiting list for bariatric surgery

<div><p>ABSTRACT Objective To verify the interference of the energy intake under-reporting in the determination of the dietary patterns and nutrient intakes reported by obese women in the waiting list for bariatric surgery. Methods The study included 412 women aged 20 to 45 years with a body mass index ranging from 35 to 60kg/m2 who were on waiting list for bariatric surgery. Data from three reported food intake and physical activity, body weight, and height were used for estimating the reported energy intake, physical activity level, and resting energy expenditure. Subsequently, it was checked the biological plausibility of the reported energy intakes, classifying all participants as plausible reporters or under-reporters. Exploratory factor analysis was used to determine the participants’ dietary patterns. The Mann-Whitney test assessed the reported energy and nutrient intakes between plausible reporters and under-reporters groups. The Z-test assessed the variables of plausible reporters or under-reporters in relation to all participants of the study. Results Six dietary patterns were determined for all participants of study. After excluding information from under-reporting women, only two dietary patterns remained similar to those of all participants, while three other dietary patterns presented different conformations from food subgroups to plausible reporters. The reported energy intake did not present difference for the subgroups of fruits, leaf vegetables and vegetables. However, the energetic value reported for the other food subgroups was higher for the plausible reporters. Conclusion The under-reporting of energy intake influenced the determination of dietary patterns of obese women waiting for bariatric surgery.</p></div