Preventing mother-to-child transmission: factors affecting mothers\' choice of feeding — a case study from Cameroon

This paper reports on factors influencing the decision of mothers regarding the type of feeding method for their babies in a rural setting in Cameroon. The aim of the study was to ascertain the proportion of mothers choosing the different methods of feeding, to determine the various factors influencing their choices, and to ascertain the relationships of these factors to their respective choices. Questionnaires were used on 108 HIV-positive mothers who had delivered babies and who were administered nevirapine at least 3 months prior to the study. A focus group discussion with mothers also took place. Findings were that more mothers (84%) chose breastfeeding than artificial feeding (16%), while a minority (4%) selected mixed feeding. Factors found to militate against artificial feeding were cost (69%), stigma (64%), family pressure (44%), inconvenience in preparation/administration (38%), prior education from health workers (23%), and loss of special attention from family (8%). On the other hand, advice of health worker (44%), ill health (19.5%), free milk (12.5%), job pressure (12.5%) and loss of beauty (12.5%) were found to militate against breastfeeding. A direct relationship was also found between age, educational level, income size, marital status and choice of feeding. Policies targeting stigma reduction and socio-cultural factors affecting the choice of feeding are needed to optimise uptake of the less risky methods of feeding which could in turn contribute to a reduction in transmission. Key words: HIV/AIDS, mother-to-child transmission prevention, feeding. La prévention de la transmission mère-enfant: les facteurs influençant le choix de la mère sur la méthode d'allaitement – une etude de cas du Cameroun RÉSUMÉ Cette communication présente des facteurs qui influencent la décision des mères concernant la méthode d\'allaitement de leur nourrissons, en zone rurale au Cameroun. Le but de cette étude était de s\'assurer de la proportion de mères qui choisissent de méthodes différentes d\'allaitement, de déterminer les facteurs influençant leur choix et d\'étudier la relation entre ces facteurs et les méthodes d\'allaitement choisies. Pour recueillir des données, un questionnaire a été utilisé auprès de 108 mères séropositives qui ont des nourrissons. Ces mères étaient sur le traitement de la névirapine depuis au moins 3 mois avant le début de cette étude. Une discussion d\'un groupe de foyer de mères a eu lieu. Les résultats ont montré que plus de 84% de mères ont choisi l\'allaitement maternel contre 16% qui ont choisi l\'allaitement artificiel alors qu\'une minorité (4%) ont choisi l\'allaitement mixte (maternel et artificiel). Les raisons contre l\'allaitement artificiel sont les suivants: le coût (69%); la stigmatisation (64%); les pressions familiales (44%); les inconvénients liés à la préparation et l\'administration du lait artificiel (38%); une éducation préliminaire de la part du personnel soignant (23%) et le manque de soins particuliers de la part de la famille (8%). D\'autre part, les facteurs qui favorisent l\'allaitement artificiel sont les suivants: les conseils du personnel de santé (44%); la mauvaise santé (19.5%); du lait artificiel gratuit (12.5%) et la perte de beauté (12.5%). Nous avons constaté une relation entre l\'âge de la femme, le niveau d\'éducation, le niveau du revenu, le statut civil et le choix d\'allaitement. Il est nécessaire de mettre en place des politiques visant la réduction de la stigmatisation et les facteurs socioculturels qui influencent le choix d\'une méthode d\'allaitement afin de maximiser une compréhension de méthodes d\'allaitement à moindre risque qui par la suite pourrait contribuer à la réduction de transmission. Mots clés :VIH/SIDA, prévention de la transmission mère-enfant, allaitement. Sahara J Vol.1(3) 2004: 132-13

Understanding innovation platform effectiveness through experiences from west and central Africa

Innovation platforms (IPs) are a way of organizing multistakeholder interactions, marshalling ideas, people and resources to address challenges and opportunities embedded in complex settings. The approach has its roots in theories of complexity, the concept of innovation systems and practices of participatory action research. IPs have been widely adopted across Africa and beyond in recent years as a “must have” tool in a range of “for development” modes of agricultural research. Our experiences with establishing and facilitating nine IPs in local settings in west and central Africa contribute to understanding factors that impact on their effectiveness. The nine IPs were variously focused on developing dairy, crop and/or meat value chains by strengthening mixed crop-livestock production systems or seed systems. Using case study methods, we identified variables that contribute to explaining the performance of these IPs in relation to six domains of change in the agricultural system and the sustainability of changes. Thematic analysis was guided by a conceptual framework which grouped variables into four categories (context, structure, conduct, and process) that interact to influence IP performance. Stronger market connections and value chains were generated through some of these IPs but the most prevalent changes overall were in farm productivity and technical knowledge of producers. The structures evolved in some IPs, akin to those of producer collectives, suggested they were filling an institutional gap locally. The effect of the IPs on deeper level institutions that influence agricultural systems and food security was modest, constraining prospects for the IPs to generate impact at scale. Impacts from the IPs on research and development organisations were uncommon but had transformative significance. Our conceptual framework did not offer optimal guidance to understanding how the many variables that contributed to performance of these IPs combined and sequenced, but the pattern of interactions was consistent with increased social capital being the prime mediator for change. Achieving greater prospects for transformational change and impact at scale warrants at least equal attention to three other interconnected change pathways: through markets, institutions and innovation capacity. Important factors for increased impact are individuals and organisations with capacity to purposefully build and manage inter-organisational and cross-scale networks, early diagnostic studies of the institutional landscape, and adaptive processes of critical reflection and learning that continue beyond the short term

Sensitivity and discovery potential of the proposed nEXO experiment to neutrinoless double beta decay

The next-generation Enriched Xenon Observatory (nEXO) is a proposed experiment to search for neutrinoless double beta ($0\nu\beta\beta$) decay in $^{136}$Xe with a target half-life sensitivity of approximately $10^{28}$ years using $5\times10^3$ kg of isotopically enriched liquid-xenon in a time projection chamber. This improvement of two orders of magnitude in sensitivity over current limits is obtained by a significant increase of the $^{136}$Xe mass, the monolithic and homogeneous configuration of the active medium, and the multi-parameter measurements of the interactions enabled by the time projection chamber. The detector concept and anticipated performance are presented based upon demonstrated realizable background rates.Comment: v2 as publishe

Characterization of an Ionization Readout Tile for nEXO

A new design for the anode of a time projection chamber, consisting of a charge-detecting "tile", is investigated for use in large scale liquid xenon detectors. The tile is produced by depositing 60 orthogonal metal charge-collecting strips, 3~mm wide, on a 10~\si{\cm} $\times$ 10~\si{\cm} fused-silica wafer. These charge tiles may be employed by large detectors, such as the proposed tonne-scale nEXO experiment to search for neutrinoless double-beta decay. Modular by design, an array of tiles can cover a sizable area. The width of each strip is small compared to the size of the tile, so a Frisch grid is not required. A grid-less, tiled anode design is beneficial for an experiment such as nEXO, where a wire tensioning support structure and Frisch grid might contribute radioactive backgrounds and would have to be designed to accommodate cycling to cryogenic temperatures. The segmented anode also reduces some degeneracies in signal reconstruction that arise in large-area crossed-wire time projection chambers. A prototype tile was tested in a cell containing liquid xenon. Very good agreement is achieved between the measured ionization spectrum of a $^{207}$Bi source and simulations that include the microphysics of recombination in xenon and a detailed modeling of the electrostatic field of the detector. An energy resolution $\sigma/E$=5.5\% is observed at 570~\si{keV}, comparable to the best intrinsic ionization-only resolution reported in literature for liquid xenon at 936~V/\si{cm}.Comment: 18 pages, 13 figures, as publishe