34 research outputs found
Pulmonary Embolism Revealing Idiopathic Membranous Glomerulonephritis
We describe a case of a 55-year-old man who presented with pulmonary embolism and who was found to have nephrotic syndrome due to idiopathic membranous nephropathy. There are no other signs of nephrotic syndrome such as edema
Cancers du larynx etude retrospective Ă propos de 90 cas
Objectif : Le cancer du larynx est parmi les premiers cancers de la sphĂšre oto-rhino laryngĂ©e. La dysphonie constitue le maĂźtre symptĂŽme rĂ©vĂ©lateur et peut ĂȘtre associĂ©e Ă une dyspnĂ©e selon la localisation tumorale. Il sâagit essentiellement dâun carcinome Ă©pidermoide. Lâalcoolo-tabagisme joue un rĂŽle important dans la genĂšse de ce cancer.MatĂ©riel et mĂ©thodes: Notre Ă©tude est rĂ©trospective Ă propos de 90 cas colligĂ©s sur une pĂ©riode de 18 ans (1990-2007).RĂ©sultats : La prĂ©dominance du sexe masculin est nette avec une seule femme dans notre sĂ©rie. Le pic dâĂąge est entre 60 et 70 ans. 98,9% de nos patients sont des fumeurs chroniques. 14,4% ont Ă©tĂ© suivis pour une laryngite chronique. La dysphonie a Ă©tĂ© retrouvĂ©e chez tous nos patients. Le dĂ©lai de consultation moyen est relativement long avec une moyennede 8 mois. Le point de dĂ©part de la tumeur a Ă©tĂ© le plan glottique dans 72,2% et sus glottique dans 23,4%. Le type histologique le plus frĂ©quent est le carcinome Ă©pidermoĂŻde dans 92,2%. Le bilan dâextension a systĂ©matiquement comportĂ© une endoscopie sous anesthĂ©sie gĂ©nĂ©rale avec une tomodensitomĂ©trie. La majoritĂ© de nos malades ont Ă©tĂ© classĂ©sT3-T4 et ceci dans 31,4%. Le taux de survie globale Ă 5 ans a Ă©tĂ© de 57,1%.Conclusion : Le cancer du larynx est un cancer du sujet de sexe masculin surtout alcoolo-tabagique. Le bilan endoscopique et radiologique essentiellement scanographique va permettre un bilan dâextension et guider ainsi la conduite thĂ©rapeutique. Le traitement est essentiellement chirurgical, couplĂ© parfois Ă une radiothĂ©rapie ou une chimiothĂ©rapie.Le pronostic est le plus frĂ©quemment favorable surtout si le diagnostic est prĂ©coce.Mots-clĂ©s : Larynx, Cancer, TomodensitomĂ©trie,Traitemen
Benign osteoblastoma in an unusual mastoid location
SummaryIntroductionBenign osteoblastoma (OB) is an unusual primary bone tumor. The preferred locations are the posterior arch of vertebrae and long bones. We report herein an extremely rare location of an OB in the mastoid process of the temporal bone.Case reportA 22-year-old woman presented with painful left retro-auricular swelling. Computed tomography features were suggestive of an aggressive osteolytic lesion of the left mastoid. The pathologic examination of bone curettage material revealed a benign OB. A complete resection of the tumor was performed later, with no evidence of recurrence at 1 year.Discussion/ConclusionTo our knowledge, this is the 14th reported case of OB confined to the mastoid process of temporal bone. Its histological diagnosis can be difficult and osteosarcoma is its principal differential diagnosis. Although generally regarded as benign, OB has potential for recurrence and local invasion. As such, complete resection, whenever possible, is preferred over conventional curettage
La mucormycose nasosinusienne: Diagnostic et modalites therapeutiques
La mucormycose est une infection fongique rare qui touche essentiellement les sujets immunodĂ©primĂ©s et notamment diabĂ©tiques. La localisation de cette maladie est surtout nasosinusienne. Son pronostic reste mauvais malgrĂ© le dĂ©veloppement des moyens de prise en charge. Nous rapportons deux cas de mucormycose nasosinusienne Ă travers lesquels nous discutons les aspects cliniques et radiologiques, ainsi que les moyens thĂ©rapeutiques de cette maladie. Il sâagit dâun homme et dâune femme ĂągĂ©s respectivement de 56 et 52 ans. Le premier Ă©tait diabĂ©tique et la deuxiĂšme insuffisante rĂ©nale. LâĂ©volution Ă©tait lente dans le premier cas et trĂšs rapide dans le deuxiĂšme. Le diagnostic Ă©tait dans les deux cas histologique. LâĂ©volution Ă©tait, dans le premier cas, favorable aprĂšs traitement associant dĂ©bridement chirurgical et amphotĂ©ricine B, et dans le second rapidement fatale. Conclusion : La mucormycose nasosinusienne est une affection grave dont le pronostic peut ĂȘtre mauvais malgrĂ© le traitement.Mots clĂ©s : Infection fongique, mucormycose rhinocĂ©rĂ©brale, zygomycĂštes
Flexural Bending and Fatigue Analysis of Functionally Graded Viscoelastic Materials: Experimental and Numerical Approaches
This work synthesized a thermoplastic polymer with varying densities along one direction using additive manufacturing technology to study the dynamic and static characteristics of functionally graded viscoelastic materials (FGVMs). To describe the mechanical properties of FGVMs, an analytical formulation based on the sigmoid-law formulation was proposed. The experimental program is conducted on 3D-printed samples, and various tests are conducted to examine the performance of such materials. Furthermore, the finite element method was used to evaluate the structural system's flexural properties. The influences of FG parameters and geometrical properties on flexural and reverse bending fatigue life are analyzed. The results show that increasing porosity from 10% to 30% at a power-law index (k = 2) reduces bending strength by 31.25 percent and deflection by around 11.2 percent for VE samples. Changing the power-law exponent from 0.5 to 10 increases fatigue strength by 35 %
Prevalence of microvascular and macrovascular complications of diabetes in newly diagnosed type 2 diabetes in low-and-middle-income countries: A systematic review and meta-analysis
There is an excessive burden of diabetes complications in low-resource settings. We conducted a systematic review to determine the nature and frequency of diabetes complications in newly diagnosed with type 2 diabetes. A systematic search was performed using Medline, CINAHL and Global Health online databases from inception to July 2020. Articles reporting prevalence of microvascular or macrovascular complications within six months of type 2 diabetes diagnosis and published in English or French from low- and middle-income countries (LMICs) were eligible for analysis. Data were extracted using a standardized data extraction tool. Descriptive statistics were used to describe the prevalence of micro and macrovascular complications in newly diagnosed type 2 diabetes. Assessment of heterogeneity was conducted using the inconsistency index (I2) and Cochran-Q chi2 statistical tests. Publication bias was assessed by the Funnel plot and Egger test. A total of 3 292 records underwent title or abstract screening and 95 articles underwent full text review. Thirty-three studies describing 13 283 participants (aged 20 years and older) met the inclusion criteria. The eligible studies were from Asia (n = 24), Africa (n = 4), Oceania (n = 2), South America (n = 2) and the Caribbean (n = 1). For microvascular complications, the median prevalence (interquartile range) of retinopathy, nephropathy and neuropathy were 12% (6%-15%), 15% (7%-35%) and 16% (10%25%) respectively. For macrovascular complications, the median prevalence (interquartile range) was 10% (7%-17%) for ischaemic heart disease, 6% (1%-20%) for peripheral arterial disease and 2% (1%-4%) for stroke. There was evidence of substantial heterogeneity between studies for all outcomes (I2 > 90%. We found a high prevalence of complications in newly diagnosed type 2 diabetes in LMICs. Findings suggest that many people live with diabetes and are only diagnosed when they present with complications in LMICs. Research is needed to guide timely and effective identification of people living with diabetes in these settings
Teratome kystique mature retro-vesical de l\'adulte: a propos d\'un cas
No Abstract. African Journal of Urology Vol. 13 (2) 2007: pp. 169-17
IntĂ©rĂȘt pronostique de lâinfiltration du chorion dans les tumeurs vĂ©sicales pT1
Introduction: Les objectifs de notre travail sont dâĂ©valuer lâimpact pronostic de la profondeur dâinfiltration tumorale du chorion et de lâenvahissement ou non de la musculaire muqueuse des tumeurs pT1 de la vessie en Ă©tudiant les taux de rĂ©cidive et de progression, les survies globale, sans rĂ©cidive et sans progression.
Patients et MĂ©thodes: La relecture de toutes les lames a Ă©tĂ© effectuĂ©e pour dĂ©terminer la prĂ©sence ou non de la musculaire muqueuse, son envahissement (pT1b) ou non (pT1a) et la profondeur dâenvahissement du chorion (pT1 m: envahissement unifocal †0,5 mm ou pT1e: envahissement unifocal > 0,5 mm ou multiple).
RĂ©sultats: En fonction de lâinvasion de la musculaire muqueuse, les taux de rĂ©cidive et de progression Ă©taient plus frĂ©quents pour les tumeurs pT1b par rapport Ă celles pT1a, avec un taux de rĂ©cidive de 84.6% (p = 0,0012) et de progression de 38.5% (p = 0,003). En fonction du degrĂ© dâinvasion du chorion, la rĂ©cidive et la progression Ă©taient plus frĂ©quentes pour les tumeurs pT1e par rapport Ă celles pT1 m (respectivement 57.2 (p = 0,05) et 17.9% (p = 0.11)). La survie moyenne sans rĂ©cidive Ă©tait de 70.3 mois pour les tumeurs pT1a et 53.6 mois pour celles pT1b (p = 0,046), et elle Ă©tait de 61.7 mois pour les tumeurs pT1e et de 55.5 mois pour celles pT1 m (p = 0,85).
Conclusion: Le classement des ces tumeurs en fonction de lâimportance dâenvahissement du chorion et de lâinfiltration de la musculaire muqueuse a prouvĂ© son efficacitĂ© Ă travers les taux de rĂ©cidive et de progression tumorale chez nos malades