8 research outputs found
Psychological distress among hospital caregivers during and after the first wave of COVID-19: Individual factors involved in the severity of symptoms expression
Coronavirus disease 2019 has spread rapidly over the globe and has put an unprecedent psychological pressure on
health care workers (HCWs). The present study aimed at quantifying the psychological consequences of the
COVID-19 pandemic on HCWs during and after the first wave and identify sociodemographic, situational, and
psychological risk/protective factors for symptoms severity. An online survey was sent by e-mail to all nurses and
physicians employed by a teaching hospital in Brussels, Belgium. 542 (20,62%) completed the survey. 47%, 55%,
32% and 52% of participants reported posttraumatic stress, anxiety, depression and insomnia symptoms,
respectively, during the peak. Two to three months later, posttraumatic symptoms emerged de novo in 54% of
HCWs. It persisted in 89% of those presenting severe symptoms initially. Neuroticism was the strongest predictor
of posttraumatic stress, anxiety, and insomnia. Work overload was the strongest predictor of depression and
second predictor of posttraumatic stress, anxiety, and insomnia. Other significant predictors included being a
nurse, the number of past traumatic experiences, avoidant coping style, and expressive suppression of emotion
Research into an Association between Anhedonia and Decreased REM Latency in Moderately to Severely Depressed Patients
Anhedonia stands as a core symptom and potential trait marker of major depressive disorder (MDD). The importance of rapid eye movement sleep latency (REML) as a biological marker of depression has previously and repeatedly been studied. The aim of this paper is to analyse the relationship between anhedonia and REML in moderately to severely depressed patients. The shortened Beck Depression Inventory (BDI-13) was chosen to assess depressive symptoms and, among them, more particularly, anhedonic symptoms. Two-way ANCOVA was used for statistical analyses. A significant association between anhedonic symptoms and REML was found when the number of sleep cycles (NCy) and the severity of depression were added as covariates. Our findings suggest that REML may be a useful variable to differentiate some diagnostic subtypes of depression related to anhedonia
Method for producing antibody using "naked" expression vector expressing type II transmembrane fusion protein
publication date: 2012-04-19; filing date: 2011-10-1