61 research outputs found

    On analysis of small bore piping vibrations

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    This thesis investigates the natural frequency and vibration induced stress of small bore power plant piping. Straight piping and piping with concentrated load, such as a valve, located anywhere along the span are studied. Four different boundary conditions of fixed-free, simple-fixed, fixed-fixed and simple-simple are investigated, as any single span piping may be approximated by one of these boundary conditions. The results otained [sic] for frequency and stress coefficients in the case of straight piping are plotted. Plots of frequency factor and stress ratio for the piping with concentrated load are also presented. The results obtained for the natural frequencies are compared with the available literature, and it is observed that they are in good agreement. In the case of single span piping with concentrated load, the natural frequency asymptotically approaches that of uniform piping as the concentrated load approaches zero

    Synthesis of peptide-ligand conjugates and their applications

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    Three research areas pertaining to this dissertation, (i) synthesis strategies of peptide-ligand conjugates, (ii) their applications and (iii) chemistry of ferryls were surveyed in the introduction chapter. Next, the divergent and dual divergent strategies for the synthesis of non-heme ligand-peptide conjugates were developed. Using these strategies various peptide-ligand conjugates were synthesized via solution as well as solid phase synthesis. The scope and the functional group compatibility of these strategies were also established. The utility of the dual divergent strategy has been demonstrated by synthesizing a small library of metal-binding LHRH analogues. This work showcased the ability of the dual divergent strategy to rapidly construct the diverse array of ligand structures. In another application, the synthesis and characterization of the first ferryl-peptide conjugate was presented. In this work the reactivity and the mechanistic study for this ferryl-peptide conjugate were also described. From the mechanistic studies it has been proven that the remote benzyl group controls the stability of ferryl-peptide conjugate via an intramolecular hydrogen atom transfer mechanism

    Novel Approach for Job Offloading Technique in Mobile Cloud Computing

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    User preferences for computing have evolved as a result of recent advancements in mobile computing technologies. Mobile devices (SMDs) are still low potential computer platforms with capped memory sizes, CPU speeds, and battery life. Computationally heavy mobile apps may be run on SMDs thanks to Mobile Cloud Computing (MCC), which uses computational offloading. In both the business and academic worlds, there is rising interest in the mobile cloud computing is a new computing paradigm. Lack of a comprehensive experimental framework to use in their experiments and to evaluate their proposed work is a serious issue for mobile cloud computing researchers. Through MCC, mobile devices will be able to serve a wider variety of resource-intensive tasks while maintaining and growing their resource pools. In order to improve the mobile user experience, it places a high priority on improving energy efficiency, storage capacity, computational power, and data security. Since both the mobile device and the Cloud must determine energy-time trade-offs and decisions made on one side have an influence on the performance of the other, designing MCC systems is a challenging task. According to an examination of the MCC literature, all present models are centred on mobile devices, with the Cloud viewed as a system with infinite resources. Furthermore, no MCC-specific simulation tool is currently known to exist. To fill this need, we present in this study a Novel Approach for Job Offloading in Cloud Environments such as Google Cloud, using OCR application, while attempting to reduce energy use (Power). We are measuring the results of this experiment on both Cloud Computing and Mobile Device Computing. &nbsp

    Investigation of Thermoelectric properties of Magnetic Insulator FeRuTiSi Using First Principle Calculation

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    In this work, we have investigated the electronic structure and thermoelectric properties of quaternary heusler alloy, FeRuTiSi, using first principle DFT tools implemented in WIEN2k and BoltzTraP code. Electronic structure calculations using TB-mBJ potential shows appearance of flat band at the conduction band edge, thus electron in conduction band have the large effective mass (me*), and therefore mainly contribute for negatively large value of Seebeck coefficient (S). This alloy has indirect band gap of 0.59 eV, and shows the n-type transport behavior. Under the constant relaxation time approximation (tau = 10 -14 s), temperature dependent Seebeck coefficient, electrical conductivity (sigma), and electronic thermal conductivity (ke) were also estimated. The maximum figure-of-merit (ZT), for the FeRuTiSi compound is found to be ~0.86 at 840 K, with n-type doping, which suggests that this quaternary alloy can be a good candidate among the n-type material for thermoelectric applications in high-temperature regComment: 4 Pages, 4 figure

    Production and Purification of Pectinase by Soil Isolate Penicillium Sp and Search for Better Agro-Residue for its SSF

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    Pectinase producing microorganisms were isolated from pectin industry waste using selective isolation technique. Among them, a potential culture was identified on morphological basis as Penicillium sp. It was found to produce significant amount of extracellular pectinase under submerged fermentation process. The type of enzyme produced was subsequently identified as polygalacturonase (PG). On partial optimization, culture showed maximum enzyme production at 35 oC in a medium having pH 6.0 containing 1.5% pectin on 72 h of incubation. The PG produced by the isolate was further purified by ammonium sulphate precipitation, size exclusion and ion exchange chromatography. The molecular weight of purified enzyme was determined to be 35 kDa by SDS-PAGE. Under optimized conditions, purified PG showed 98.66 U/ml activity which was almost 12 fold higher than crude. In view of cost effective pectinase production, substrate optimization using solid state fermentation was carried out amongst which orange bagasse gave 64.50 U/gm PG activity which was higher than other natural substrates

    SYNTHESIS AND ANTIBACTERIAL SCREENING OF FEW NEW 5-MEMBERED HETEROCYCLIC SUGAR HYDRAZONES

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    Objective: The aim of this study is to synthesize, characterize, and screen some new 5-membered heterocyclic sugar hydrazones for their antibacterialactivities.Methods: A library of sugar hydrazones containing 2-benzofuryl, 2-thiophenyl, and 2-pyrrolyl motifs were synthesized. Structures of the newlysynthesized compounds were deduced based on spectral data and elemental analyses.Results: Antibacterial activity was screened against Gram-positive and Gram-negative bacterial strains. Results were compared to gentamicin.Compound 6a exhibited most potent antibacterial activity against all the tested strains.Conclusion: 2-benzofuryl derivatives were observed to be good antibacterials.Keywords: Benzofuran, Thiophene, Pyrrole, Antibacterial, Sugar

    A SURVEY OF YOGA CURRICULUM AND TRANSACTION TECHNIQUES IN GOVERNMENT AND PRIVATE INSTITUTES IN MAHARASHTRA

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    Yoga is becoming increasingly popular among the youth population as a health intervention, physical education, and recreational activity. What constitutes yoga varies, as does what is taught and how it is taught. The objectives of this study were to examine yoga curricula to identify content, teaching strategies, and assessment; wellness dimensions addressed; whether national health and physical education standards have been met; implementation of loyalty management systems; and shared constructs between yoga and educational psycholog

    Effect of Classical Hathayoga on executive functions among corporate employees

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    Background: In the fast-paced and demanding corporate world, the need for strategies to enhance cognitive abilities, particularly executive functions, has garnered increasing attention. Yoga, a holistic practice originating from ancient Eastern traditions, has gained popularity as a potential intervention to address the cognitive demands placed on modern professionals. The objective of this study was to determine whether classical hata yoga practice enhances the executive functions resulting in improved cognitive functions and reduction in perceived stress levels. Material and Methods: One hundred corporate employee subjects who had enrolled in a six months classical hatayoga practice. Their ages ranged between 24 and 50 years (group average ±S.D., 31.04±4.5 years). Those who have any chronic illness and mental illness, and those who are not willing to participate were excluded. Classical hata yoga practice was given for six months, 1hours/daily 5 days a week. At baseline and following six months, all participants completed SLCT, DLST, DVT and PSS. Results: Classical hata yoga practice showed significant change in both SLCT and DLST scores, increase (P-value< 0.000) in total attempted score, significant increase (P-value<0.000) in net score, significant reduction in wrongly attempted score (P-value<0.00) in yoga group compared to the non-significant improvements of control group, also there was significant change in total time taken and wrong attempts (P-value<0.00) of DVT in Yoga group compare to the control group, PSS scores were also significantly reduced (P-value<0.00)  in Yoga group compared to control group, there was a significant improvement in all the variables of yoga group compare to the control when compared between groups through Mann–Whitney test. Conclusions: The six months classical hata practice was successful in enhancing the  executive functions and reducing perceived stress among corporate employees
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