Stability of Externally Driven Magnetic Islands in a Helical Plasma

Influence of external resonant magnetic perturbation (RMP) on a helical plasma is numerically investigated, using a set of reduced magnetohydrodynamic equations. Coexistence of the resistive interchange mode and RMP is simulated. In nonlinear simulations, saturated magnetic islands by the RMP typically show two states: oscillating small islands and locked large islands. In the former state, rotation of magnetic islands by neoclassical transport-driven poloidal flows disturbs growth of islands. On the other hand, in the latter state, locking of poloidal flows due to the RMP and growth of islands occur simultaneously. It is found that the curvature driven current enhances magnetic reconnection, and width of the large islands overcomes that of vacuum islands

Mitosis Detection from Partial Annotation by Dataset Generation via Frame-Order Flipping

Detection of mitosis events plays an important role in biomedical research. Deep-learning-based mitosis detection methods have achieved outstanding performance with a certain amount of labeled data. However, these methods require annotations for each imaging condition. Collecting labeled data involves time-consuming human labor. In this paper, we propose a mitosis detection method that can be trained with partially annotated sequences. The base idea is to generate a fully labeled dataset from the partial labels and train a mitosis detection model with the generated dataset. First, we generate an image pair not containing mitosis events by frame-order flipping. Then, we paste mitosis events to the image pair by alpha-blending pasting and generate a fully labeled dataset. We demonstrate the performance of our method on four datasets, and we confirm that our method outperforms other comparisons which use partially labeled sequences.Comment: 8 pages, 9figures, MICCAI 2023 accepte

Object Transportation System Mimicking the Cilia of Paramecium aurelia Making Use of the Light-Controllable Crystal Bending Behavior of a Photochromic Diarylethene

The design of an object transportation system exploiting the bending behavior of surface-assembled diarylethene crystals is reported. A photoactuated smart surface based on this system can transport polystyrene beads to a desired area depending on the direction of the incident light. Two main challenges were addressed to accomplish directional motion along a surface: first, the preparation of crystals whose bending behavior depends on the direction of incident light; second, the preparation of a film on which these photochromic crystal plates are aligned. Nuclei generation and nuclear growth engineering were achieved by using a roughness-controlled dotted microstructured substrate. This system demonstrates how to achieve a mechanical function as shown by remote-controlled motion along a surface

Photoinduced swing of a diarylethene thin broad sword shaped crystal:a study on the detailed mechanism

We report a swinging motion of photochromic thin broad sword shaped crystals upon continuous irradiation with UV light. By contrast in thick crystals, photosalient phenomena were observed. The bending and swinging mechanisms are in fact due to molecular size changes as well as phase transitions. The first slight bending away from the light source is due to photocyclization-induced surface expansion, and the second dramatic bending toward UV incidence is due to single-crystal-to-single-crystal (SCSC) phase transition from the original phase I to phase IIUV. Upon visible light irradiation, the crystal returned to phase I. A similar SCSC phase transition with a similar volume decrease occurred by lowering the temperature (phase IIItemp). For both photoinduced and thermal SCSC phase transitions, the symmetry of the unit cell is lowered; in phase IIUV the twisting angle of disordered phenyl groups is different between two adjacent molecules, while in phase IIItemp, the population of the phenyl rotamer is different between adjacent molecules. In the case of phase IIUV, we found thickness dependent photosalient phenomena. The thin broad sword shaped crystals with a 3 mu m thickness showed no photosalient phenomena, whereas photoinduced SCSC phase transition occurred. In contrast, large crystals of several tens of mu m thickness showed photosalient phenomena on the irradiated surface where SCSC phase transition occurred. The results indicated that the accumulated strain, between isomerized and non-isomerized layers, gave rise to the photosalient phenomenon

Notch Filter in 70 GHz Range for Microwave Plasma Diagnostics

A notch filter for the rejection of stray light from gigahertz range heating sources was developed to protect a vulnerable microwave plasma diagnostic system. As one of the applications, we consider the installation of the notch filter into the receiver of a collective Thomson scattering diagnostic in the Large Helical Device. Experimental observations indicate that two types of notch filters are required for main and spurious mode rejection; they have very narrow, steep shapes to avoid disturbing the diagnostic signal. On the basis of numerically simulated results, notch filters were fabricated, and their performance was evaluated. An attenuation level of 35 dB at 74.746 GHz with a 3 dB bandwidth of 0.49 GHz is achieved by two pairs of resonator cavities. This attenuation is acceptable in our study

Aerosol measurements using a balloon seperated UAV -Present status for JARE54 operation-

第2回極域科学シンポジウム/第34回気水圏シンポジウム 11月14日（月） 統計数理研究所 セミナー室

Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein.

Alzheimer\u27s disease (AD) is the most common cause of dementia and understanding its pathogenesis should lead to improved therapeutic and diagnostic methods. Although several groups have developed transgenic mouse models overexpressing the human amyloid-β precursor protein (APP) gene with AD mutations, with and without presenilin mutations, as well as APP gene knock-in mouse models, these animals display amyloid pathology but do not show neurofibrillary tangles or neuronal loss. This presumably is due to differences between the etiology of the aged-related human disease and the mouse models. Here we report the generation of two transgenic cynomolgus monkeys overexpressing the human gene for APP with Swedish, Artic, and Iberian mutations, and demonstrated expression of gene tagged green fluorescent protein marker in the placenta, amnion, hair follicles, and peripheral blood. We believe that these nonhuman primate models will be very useful to study the pathogenesis of dementia and AD. However, generated Tg monkeys still have some limitations. We employed the CAG promoter, which will promote gene expression in a non-tissue specific manner. Moreover, we used transgenic models but not knock-in models. Thus, the inserted transgene destroys endogenous gene(s) and may affect the phenotype(s). Nevertheless, it will be of great interest to determine whether these Tg monkeys will develop tauopathy and neurodegeneration similar to human AD