689 research outputs found

    Outsourcing to self-employed knowledge workers: What are the key success factors?

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    This paper reveals the lack of discovery of the interrelationships between the various factors identified as key factors in building successful in situations where organisations outsource knowledge work to self employed management consultants. Masterful management of these success factors could lead to fruitful outcomes for both clients and consultants alike. In addition, consultants mastering these factors could gain a competitive advantage in a highly competitive profession. This paper reviews both academic and practitioner literature in relation to factors that are seen as impacting significantly on consulting assignment outcomes for both client and consultant and highlights the dearth of research surrounding the investigation of the interplay, connectedness and relationship between the various factors identified in isolation in the existing literature. In addressing this gap, a conceptual framework is proposed with a broad research agenda with seven propositions to establish the linkages between the significant success factors identified in the literature. This paper makes a unique contribution towards future research in this respect through the provision of a clear conceptual framework and robust research agenda

    Gaining the competitive edge: The key to successful client consultant relationships

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    This paper reveals the lack of discovery of the interrelationships between the various factors identified as key factors in building successful in client-consultant relationships. Masterful management of these success factors could lead to fruitful outcomes for both clients and consultants alike. In addition, consultants mastering these factors could gain a competitive advantage in a highly competitive profession. This paper reviews both academic and practitioner literature in relation to factors that are seen as impacting significantly on consulting assignment outcomes for both client and consultant and highlights the dearth of research surrounding the investigation of the interplay, connectedness and relationship between the various factors identified in isolation in the existing literature. In addressing this gap, a conceptual framework is proposed with a broad research agenda with seven propositions to establish the linkages between the significant success factors identified in the literature. This paper makes a unique contribution towards future research in this respect through the provision of a clear conceptual framework and robust research agenda

    Variations in the squamous part of the occipital bone in medieval and contemporary cranial series from Bulgaria

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    The squamous part of the occipital bone is a place of many different variations. They are a result of faulty ossification in the occipital squama or due to the presence of sutural bones in the lambda region. As their differentiation is intricate because of the various criteria used, the issue of their recognition in the adult skull still remains difficult even though they can be clearly distinguished at a younger age. The aim of the present study was to compare the frequency of interparietal, preinterparietal and sutural bones in the lambda region in medieval male and female cranial series as well as between medieval and contemporary male series from Bulgaria. We also discuss the development of the occipital squama in order to set clearer criteria for further differentiation of such variations in the adult skull. In the reviewed 3 cranial series, the variations in the squamous portion of the occipital bone were observed with a low frequency. The incidence of preinterparietal bones was more common than the interparietal ones. The sutural bones in the lambda region were numerous in the series. No statistically significant sex or intergroup differences were established. So even if these anatomical variations are relatively rare, the understanding of them is of significance for many disciplines like anthropology, comparative and developmental anatomy, clinical and forensic medicine.

    Facial soft tissue thicknesses in Bulgarian adults: relation to sex, body mass index and bilateral asymmetry

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    Background: The aim of the study is to measure the facial soft tissue thicknesses (STTs) in Bulgarians, to evaluate the relation of the STTs to the nutritional status, sex and bilateral asymmetry, and to examine the correlations between the separate STTs as well as between the STTs and body weight, height, and body mass index (BMI). In the present study, the facial STTs were measured on computed tomography scans of the head of Bulgarian adults. Materials and methods: The STTs were measured at 7 midline and 9 bilateral landmarks. The measurements were performed in the free software InVesalius in the axial and sagittal planes. The mean, standard deviation, minimum and maximum values, median and coefficient of variation were reported for the STT at each landmark according to the sex and BMI category. The BMI, sex and bilateral differences were assessed for statistical significance. Pearson correlation analysis was applied to assess the strength and direction of the relationships between the STTs and body height, weight and BMI, as well as between separate STTs. Results and Conclusions: The facial soft tissues in Bulgarian adults changed in accordance with the nutritional status of the individual and in both sexes all STTs augmented with the increasing BMI. For both normal and overweight BMI categories, males had more soft tissue at the majority of facial points than females, as the only exceptions were observed in the cheek zone, where STTs were thicker in females. Significant bilateral differences were observed in either sex and BMI category. Stronger correlations were established for the STTs in the jaw region and between the cheek and jaw soft tissues. Besides, the correlations between the homologous bilateral landmarks were among the strongest ones

    Egg Quality Characteristics in Autochthonous Genotypes of Chickens Raised on Macedonian Rural Farms

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    Egg quality characteristics of three different autochthonous chicken phenotypes (phenotype having ashy-silvery-brown leghorn laced plumage color, phenotype having light brown spangled plumage color and phenotype having black or blue plumage color) were examined. These types of chickens are mainly raised as backyard rural area flocks in the villages of R. Macedonia. The data were collected through first systematic approaches in phenotypical identification and characterisation of these autochthonous genotypes realized recently. Three small flocks of old hens collected from different villages and placed in control pens were established. No data about number of eggs/hen/year is available for the established flocks. Further investigations are needed to record productive (number of egg produced) and reproductive data. The plan was that additional, yearly production records be collected from the flock produced as offspring from established flock of old hens collected from different villages and placed in control pens. Set of 90 eggs was collected (30 eggs from each plumage phenotype) and basic egg quality parameters measured. Egg size (weight) was 50.71g for brown laced plumage phenotype, 60.48g for blue plumage phenotype and 52.6 g for light brown spangled plumage phenotype. Egg shell strength was 3965, 3628 and 3924 g/cm2 for brown laced, blue and brown spangled plumage phenotype, respectively. Light brown spangled plumage phenotype had the highest value of yolk color (10.29) and Hough Units (76.63) compared to brown laced (10.08 and 75.27) and blue (9.09 and 71.65) plumage phenotype

    Characterizing RNA Dynamics at Atomic Resolution Using Solution-state NMR Spectroscopy

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    Many recently discovered non-coding RNAs do not fold into a single native conformation, but rather, sample many different conformations along their free energy landscape to carry out their biological function. Unprecedented insights into the RNA dynamic structure landscape are provided by solution-state NMR techniques that measure the structural, kinetic, and thermodynamic characteristics of motions spanning picosecond to second timescales at atomic resolution. From these studies a basic description of the RNA dynamic structure landscape is emerging, bringing new insights into how RNA structures change to carry out their function as well as applications in RNA-targeted drug discovery and RNA bioengineering

    Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology

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    BACKGROUND: Early life stress (ELS) is consistently associated with increased risk for subsequent psychopathology. Individual differences in neural response to reward may confer vulnerability to stress-related psychopathology. Using data from the ongoing Duke Neurogenetics Study, the present study examined whether reward-related ventral striatum (VS) reactivity moderates the relationship between retrospectively reported ELS and anhedonic symptomatology. We further assessed whether individual differences in reward-related VS reactivity were associated with other depressive symptoms and problematic alcohol use via stress-related anhedonic symptoms and substance use-associated coping. METHOD: Blood oxygen level-dependent functional magnetic resonance imaging (fMRI) was collected while participants (n = 906) completed a card-guessing task, which robustly elicits VS reactivity. ELS, anhedonic symptoms, other depressive symptoms, coping behavior, and alcohol use behavior were assessed with self-report questionnaires. Linear regressions were run to examine whether VS reactivity moderated the relationship between ELS and anhedonic symptoms. Structural equation models examined whether this moderation was indirectly associated with other depression symptoms and problematic alcohol use through its association with anhedonia. RESULTS: Analyses of data from 820 participants passing quality control procedures revealed that the VS × ELS interaction was associated with anhedonic symptoms (p = 0.011). Moreover, structural equation models indirectly linked this interaction to non-anhedonic depression symptoms and problematic alcohol use through anhedonic symptoms and substance-related coping. CONCLUSIONS: These findings suggest that reduced VS reactivity to reward is associated with increased risk for anhedonia in individuals exposed to ELS. Such stress-related anhedonia is further associated with other depressive symptoms and problematic alcohol use through substance-related coping
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