51 research outputs found

    INDIVIDUAL AND GENDER DIFFERENCES IN PERSONALITY INFLUENCE THE DIAGNOSIS OF MAJOR DEPRESSIVE DISORDER

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    Background: In order to explore whether gender differences are present in self-reports on personality measures when all Major Depressive Disorder (MDD) participants are diagnosed at an equal intensity, the aim of this study was to investigate individual and gender differences in personality between healthy participants and those suffering from severe feature MDD. Subjects and methods: The sample consisted of 632 participants: 385 in the healthy control group and 247 MDD, the latter comprised of patients in their first diagnosed episode or recurrent. The Hamilton Depression Rating Scale (HAM-D) was used to measure symptom severity. Beck’s Depression Inventory was administered when depression symptoms had lessened, establishing it as minor when filling out the personality questionnaire (NEO-PI-R). Results: The results indicate a broad difference in personality between the healthy control and the MDD groups. High neuroticism and low extraversion, accompanied by low scores on openness and conscientiousness, were the most important personality dimensions in understanding distinctions. While agreeableness did not indicate any important role, it did significantly influence the understanding of gender differences within groups. Females were found more agreeable in both groups, but those from the healthy group were also more open and conscientiousness than healthy males. Females from the MDD group were found to be also higher on neuroticism than males of the same group. Conclusions: A general conclusion from the study is that personality dimensions are more important in understanding vulnerability to depression in comparison to gender differences in personality within groups. As females in the MDD group tend to self-report higher levels of agreeableness and neuroticism than do males in the same group when the level of their depression is categorized as equal MDD-severe type, this may influence practitioners to unequally diagnose depression in males and females

    Comparison of Essential Metals in Different Pork Meat Cuts from the Serbian Market

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    AbstractPork consumption in Serbia accounts for a large share of total meat consumption. Pork is valuable sources of nutrients. We analyzed metal content in three different cuts of pork collected from the Serbian market during 2014. Analyses of the following isotopes: zinc (66Zn), copper (63Cu) and iron (57Fe) were performed by ICP-MS. Our data show that Zn, Cu and Fe were present in significantly different levels in hind leg, loin and shoulder, and that shoulder meat was richest in the analyzed metals. The differing mineral status of different pork cuts implies differences in their nutritional benefits for the human diet

    Comparison of two Analytical Methods (ELISA and LC-MS/MS) for Determination of Aflatoxin B1 in Corn and Aflatoxin M1 in Milk

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    AbstractThe aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B1 in corn and aflatoxin M1 in milk. Samples of corn (n=100) and milk (n=250) were simultaneously analyzed using ELISA and LC-MS/MS methods, after the severe drought that affected Serbia in summer 2012 resulting in occurrence of aflatoxin B1 in corn and aflatoxin M1 in milk. Regression analysis showed higher level of agreement between aflatoxin B1 samples (R2=0.994), compared to aflatoxin M1 samples (R2=0.920). However, both techniques were satisfactory in meeting the requirements for official control purposes

    Živa u različitim vrstama morskih riba na srpskom tržištu

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    Proučavanje žive (Hg) u marinskim sistemima je od velikog interesa, s obzirom da je reč o toksičnom metalu koji ima sposobnost bioakumulacije i biomagnifikacije u lancu ishrane. Vodeni sistemi, a time i ribe, mogu biti kontaminirani živom kao posledicom zagađenja životne sredine prirodnim procesima (vulkanske erupcije, klimatske promene itd.) i antropogenim izvorima zagađenja (industrija, rudarstvo itd.). Živa (Hg) može postojati kao elementarna, neorganska i organska živa. Najtoksičniji oblik žive je metil živa (MetHg) koja čini od 70-100% ukupne Hg u ribi. Naučna ispitivanja ukazuju da velike količine žive u hrani mogu negativno uticati na razvoj fetusa i izazvati oštećenja mozga i jetre. Cilj ovog rada bio je ispitivanje sadržaja žive u jestivim delovima tri vrste morske ribe na tržištu Srbije: oslić - Merluccius merluccius (n=84), skuša - Scomber scombrus (n=35) i papalina - Sprattus sprattus (n=17)). Prosečna potrošnja ribe u Srbiji iznosi oko 5 kg po glavi stanovnika, što je znatno niže u poređenju sa EU prosekom (21 kg po glavi stanovnika). Svi uzorci uzeti su i analizirani tokom 2014. godine. Analiza sadržaja žive urađena je primenom induktivno-kuplovane plazme sa masenom spektrometrijom (ICP-MS), merenjem izotopa 202Hg. Najviša srednja vrednost sadržaja žive utvrđena je u uzorcima skuše (0,056 mg/kg), zatim kod oslića (0,034 mg/kg), a najniža kod papaline (0,016 mg/kg). Maksimalno dozvoljene količine Hg u ispitanim ribama, koje su definisane zakonskom regulativom Srbije [MDK (oslić, papalina) = 500 ng/g, MDK (skuša) = 1000 ng/g] nisu prekoračene u svim ispitanim uzorcima. Statističkom evaluacijom dobijenih rezultata ustanovljeno je da postoji statistički zanačajna razlika (p<0,005) u sadržaju Hg između oslića i skuše, kao i između skuše i papaline. Za procenu unosa Hg konzumiranjem ribe korišćeni su podaci iz „GEMS/Food Consumption Cluster Diets database“. Prema ovom izvoru, procenjena prosečna nedeljna potrošnja morske ribe u Srbiji iznosi 106,4 g. Koristeći podatke iz ove studije izračunat je nedeljni unos Hg, baziran na srednjoj vrednosti sadržaja Hg u konzumiranoj ribi i prosečnoj telesnoj težini čoveka od 70 kg. Na osnovu izračunatih vrednosti za nedeljni unos Hg (oslić: 0,051-0,208 µg/kg telesne težine; skuša: 0,086-0,289 µg/kg telesne težine; papalina: 0,025-0,050 µg/kg telesne težine) može se zaključiti da je unos žive pri konzumaciji oslića, skuše i papaline znatno niži od preporučenih graničnih vrednosti svetske zdravstvene organizacije (1,6 µg MetHg /kg telesne težine)

    Disseminated Neonatal Herpes Caused by Herpes Simplex Virus Types 1 and 2

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    Disseminated neonatal herpes simplex virus (HSV) infection is characterized by progressive multiple organ failure and high mortality rates. It can result from infection with either HSV-1 or HSV-2. We report a case of disseminated neonatal herpes that was caused by HSV-1 and HSV-2

    Analysis of cardiac manifestation and treatment of multisystem inflammatory syndrome in children related to SARS-CoV-2

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    Cardiovascular manifestations are common (35–100%) in the multisystem inflammatory syndrome in children. Our study aimed to analyze treatment impact and cardiovascular involvement in patients with multisystem inflammatory syndrome in children. The retrospective cohort included 81 patients treated between April 2020 and December 2021 (9.3±4.6 years). Elevated cardiac troponin I and pro-B-type natriuretic peptide were observed in 34.2% and 88.5% of patients, respectively. Myocardial dysfunction was observed in 50.6%. Children older than 10 years had a 4-fold increased risk of myocardial dysfunction (odds ratio [OR] 3.6, 95% confidence interval [CI] 1.4-8.9; p=0.006). A moderate negative correlation was proved between left ventricle ejection fraction and C-reactive protein (rr = - 0.48; p < 0.001). More than one-fifth of the patients presented with shock. Coronary artery dilatation was observed in 6.2% of patients. Mild pericardial effusion was detected in 27.1% of children. On standard electrocardiogram, 52.6% of children had negative T waves in the inferior and/or precordial leads; transient QTc prolongation was registered in 43% of patients. Treatment failure was observed in 19 patients. Patients initially treated with intravenous immunoglobulins had 10-fold higher chances for treatment failure than patients treated with corticosteroids (OR 10.6, 95% CI 3,18 – 35.35; p < 0.001). Cardiovascular manifestations were observed in more than half of the patients, with acute myocardial dysfunction being the most common, especially in children older than 10 years. We established a negative association between the degree of elevation of inflammatory markers and left ventricular ejection fraction. Patients treated with intravenous immunoglobulins who had cardiovascular manifestations had treatment failures more frequently than patients treated with corticosteroids

    Case report: Spontaneous rupture of leiomyosarcoma uteri 8 months after primary laparoscopic surgery of STUMP

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    IntroductionLeiomyosarcoma (LMS), together with smooth muscle tumors of uncertain malignant potential (STUMP) and benign leiomyomas, belongs to a heterogeneous group of uterine neoplasms. According to the World Health Organization, tumors originating from uterine smooth muscle fibers are the second most frequent tumors. It is challenging to distinguish between STUMP and LMS because of an overlap of symptoms, lack of a precise definition, and unequivocal information obtained using imaging diagnostic methods. Following myomectomy or hysterectomy with laparoscopic or laparotomy surgery and a definitive histological diagnosis of STUMP, the course of treatment is determined by the need to preserve fertility. In 2014, the U.S. Food and Drug Administration published an alert that unprotected laparoscopic morcellation is correlated with a 3-fold higher likelihood of dissemination of malignant cells and disease progression. Unprotected morcellation was independently associated with a higher risk of disease recurrence after demolition or conservative surgery, with a relative risk of 2.94.ConclusionHematoperitoneum resulting from the spontaneous rupture of a uterine tumor is a rare gynecological emergency, with very few cases reported in the last decade

    Kant i prosvetiteljstvo - moderna ontologija aktuelnosti

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    Polazeći od jedne Fukoove opaske o važnosti Kantovog razumevanja\ud prosvetiteljstva za modernu filozofiju uopšte, u ovom tekstu pokušavamo da sledimo trag veze između pitanja o aktuelnosti, prosvetiteljstva i moderne kod Kanta. Ideje slobode i subjektivnosti uočavamo kao nezaobilazne za razumevanje kantovskog prosvetiteljskog projekta i njegove aktuelnosti. U tekstu pokušavamo da pokažemo kako se kod Kanta nailazi na specifično moderno shvatanje aktuelnosti koje ima dalekosežne ontološke posledice, naročito u pogledu kategorije (ne)mogućnosti. Na osnovu sprovedenih analiza dolazimo do teze da se odgovor na pitanje o aktuelnosti prosvetiteljstva ispostavlja kao ulog u borbi za ostvarenje nemogućeg.\u

    Diastolic function of the nonfiling human heart

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