The Kharkov X-ray Generator Facility NESTOR

WEPWA060 - ISBN 978-3-95450-122-9International audienceThe last few years the sources of the X-rays NESTOR based on a storage ring with low beam energy and Compton scattering of intense laser beam are under design and development in NSC KIPT. The main task of the project is to develop compact intense X-ray generator on the base of relatively cheap accelerator equipment and up-to-date laser technologies. The paper is devoted to description of the last results on construction and commissioning of the facility

Possibilities of using integrated learning in teaching English in a non-linguistic college

In the current conditions, apart from high-quality professional education, a crucial component of a specialist's competitiveness is the knowledge of a foreign language (further on - FL). Because of this, during the training of higher educational institutions' students, learning a FL requires considering professional specifics and its orientation on actualizing the professional activity tasks. Hence, methods of teaching a FL as a science are faced with the aim of searching for the optimal ways of reaching a sufficient level of FL knowledge for professional goals. Therefore, the aim of present article is to discuss the specifics of various methods of teaching a FL for professional communication and the possibilities of using them in a nonlinguistic college. In the context of present study, integrated learning is defined as learning, in which the focus is shifted from isolated teaching of a FL for professional communication to integration of learning the language with studying special disciplines. Analysis of theoretical developments and conduction of an experimental study showed that teaching a FL for professional communication on the basis of the CLIL methodology is efficient for students of a non-linguistic college. © 2017

Possibilities of using integrated learning in teaching English in a non-linguistic college

In the current conditions, apart from high-quality professional education, a crucial component of a specialist's competitiveness is the knowledge of a foreign language (further on - FL). Because of this, during the training of higher educational institutions' students, learning a FL requires considering professional specifics and its orientation on actualizing the professional activity tasks. Hence, methods of teaching a FL as a science are faced with the aim of searching for the optimal ways of reaching a sufficient level of FL knowledge for professional goals. Therefore, the aim of present article is to discuss the specifics of various methods of teaching a FL for professional communication and the possibilities of using them in a nonlinguistic college. In the context of present study, integrated learning is defined as learning, in which the focus is shifted from isolated teaching of a FL for professional communication to integration of learning the language with studying special disciplines. Analysis of theoretical developments and conduction of an experimental study showed that teaching a FL for professional communication on the basis of the CLIL methodology is efficient for students of a non-linguistic college. © 2017

Design, synthesis, antibacterial activity and toxicity of novel quaternary ammonium compounds based on pyridoxine and fatty acids

A diverse series of 43 novel “soft antimicrobials” based on quaternary ammonium pyridoxine derivatives which include six-membered acetals and ketals of pyridoxine bound via cleavable linker moieties (amide, ester) with a fragment of fatty carboxylic acid was designed. Nine compounds exhibited in vitro promising antibacterial activity against Gram-positive and Gram-negative bacterial strains with MIC values comparable with reference antiseptics miramistin, benzalkonium chloride and chlorohexidine. On various clinical isolates, the lead compounds 6i and 12a exhibited antibacterial activity comparable with that of benzalkonium chloride while higher than that of miramistin. Moreover, 6i and 12a were able to kill bacteria embedded into the matrix of mono- and dual species biofilms. The treatment of bacterial cells by either 6i and 12a lead to fast depolarization of the membrane suggesting that the membrane is an apparent molecular target of compounds. 6i and 12a were non mutagenic neither in SOS-chromotest nor in Ames test and non-toxic in vivo at acute oral (LD50 > 2000 mg/kg) and cutaneous administration (LD50 > 2500 mg/kg) on mice. Taken together, our data allow suggesting described active compounds as promising starting point for the new antibacterial agents development

The Kharkov X-ray Generator Facility NESTOR

WEPWA060 - ISBN 978-3-95450-122-9International audienceThe last few years the sources of the X-rays NESTOR based on a storage ring with low beam energy and Compton scattering of intense laser beam are under design and development in NSC KIPT. The main task of the project is to develop compact intense X-ray generator on the base of relatively cheap accelerator equipment and up-to-date laser technologies. The paper is devoted to description of the last results on construction and commissioning of the facility