45 research outputs found
Optimisatoin tactics of disgnostic and treatment of women of reproductive age with dysplastic lesions of sguamosus cervical epitelium and hyperproliferative diseases of the uterus
Cervical cancer frequency ranks second in the structure of cancer among women. HPV is the only proven etiological factor of precancerous lesions and cervical cancer.Given the increasing frequency of adenomyosis and leiomyoma of the uterus and pathology of the cervical epithelium in women with unfulfilled reproductive function and the extension age limits of the reproductive period, organ-preserving methods of treatmentof these pathological conditions is a main priority in gynecology.The aim of this research was to develop approaches to the treatment of cervical pathology in women with hyperproliferative diseases of the uterus
ΠΠ΅ΡΠ΅Π±ΡΠ³ Π²Π°Π³ΡΡΠ½ΠΎΡΡΡ, ΠΏΠΎΠ»ΠΎΠ³ΡΠ² ΡΠ° ΠΎΡΡΠ½ΠΊΠ° ΡΡΠ°Π½Ρ Π½ΠΎΠ²ΠΎΠ½Π°ΡΠΎΠ΄ΠΆΠ΅Π½ΠΈΡ Π² Π·Π°Π»Π΅ΠΆΠ½ΠΎΡΡΡ Π²ΡΠ΄ Π°ΠΊΡΡΠ΅ΡΡΡΠΊΠΎΡ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΡΡ ΠΌΠ°ΡΠ΅ΡΡΠ², Π·Π°ΠΉΠ½ΡΡΠΈΡ Π² Ρ ΡΠΌΡΡΠ½ΠΎΠΌΡ Π²ΠΈΡΠΎΠ±Π½ΠΈΡΡΠ²Ρ
Π ΠΏΡΠΎΡΠ΅ΡΡ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π±ΡΠ»ΠΎ ΠΏΡΠΎΠ°Π½Π°Π»ΡΠ·ΠΎΠ²Π°Π½ΠΎ 50 ΡΠ½Π΄ΠΈΠ²ΡΠ΄ΡΠ°Π»ΡΠ½ΠΈΡ
ΠΊΠ°ΡΡ ΡΠΏΠΎΡΡΠ΅ΡΠ΅ΠΆΠ΅Π½Π½Ρ Π²Π°Π³ΡΡΠ½ΠΈΡ
Π² ΠΆΡΠ½ΠΎΡΡΠΉ ΠΊΠΎΠ½ΡΡΠ»ΡΡΠ°ΡΡΡ ΠΠΠ’ Β«Π‘ΡΠΌΠΈΡ
ΡΠΌΠΏΡΠΎΠΌΒ», ΡΡΡΠΎΡΡΡ ΠΏΠΎΠ»ΠΎΠ³ΡΠ² ΡΠΈΡ
ΠΆΡΠ½ΠΎΠΊ, Π° ΡΠ°ΠΊΠΎΠΆ ΡΡΡΠΎΡΡΡ ΡΠΎΠ·Π²ΠΈΡΠΊΡ Π½ΠΎΠ²ΠΎΠ½Π°ΡΠΎΠ΄ΠΆΠ΅Π½ΠΈΡ
. ΠΡΠ² ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΉ ΡΠ΅ΡΠ΅Π»ΡΠ½ΠΈΠΉ Π°Π½Π°Π»ΡΠ· Π°Π½Π°ΠΌΠ½Π΅ΡΡΠΈΡΠ½ΠΈΡ
Π΄Π°Π½ΠΈΡ
ΠΎΠ±ΡΡΠ΅ΠΆΡΠ²Π°Π½ΠΈΡ
ΠΆΡΠ½ΠΎΠΊ, ΡΡΠ°Π½ ΠΏΡΠ΅ΠΌΠΎΡΠ±ΡΠ΄Π½ΠΎΠ³ΠΎ ΡΠΎΠ½Ρ, ΠΏΠ΅ΡΠ΅Π±ΡΠ³ Π²Π°Π³ΡΡΠ½ΠΎΡΡΡ, ΠΏΠΎΠ»ΠΎΠ³ΡΠ², ΡΠ° ΠΏΡΡΠ»ΡΠΏΠΎΠ»ΠΎΠ³ΠΎΠ²ΠΎΠ³ΠΎ ΠΏΠ΅ΡΡΠΎΠ΄Ρ, ΠΏΠ΅ΡΡΠΎΠ΄Ρ Π½ΠΎΠ²ΠΎΠ½Π°ΡΠΎΠ΄ΠΆΠ΅Π½ΠΎΡΡΡ. ΠΠ²Π΅ΡΡΠ°Π»ΠΈ ΡΠ²Π°Π³Ρ Π½Π° Π³Π΅ΡΡΠ°ΡΡΠΉΠ½ΠΈΠΉ Π²ΡΠΊ Π΄ΡΡΠ΅ΠΉ, ΡΡΠ°Π½ ΠΏΡΠΈ Π½Π°ΡΠΎΠ΄ΠΆΠ΅Π½Π½Ρ ΡΠ° ΠΏΠ΅ΡΠ΅Π±ΡΠ³ ΡΡ
ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΡ Π°Π΄Π°ΠΏΡΠ°ΡΡΡ. ΠΡΡΠΌ ΡΡΠΎΠ³ΠΎ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΊΠ°ΡΠ°ΠΌΠ½Π΅ΡΡΠΈΡΠ½Π΅ ΡΠΏΠΎΡΡΠ΅ΡΠ΅ΠΆΠ΅Π½Π½Ρ Π·Π° Π΄ΡΡΡΠΌΠΈ ΡΠ° ΠΎΡΡΠ½ΠΊΠ° ΡΡ
ΡΡΠ·ΠΈΡΠ½ΠΎΠ³ΠΎ Ρ Π½Π΅ΡΠ²ΠΎΠ²ΠΎ-ΠΏΡΠΈΡ
ΡΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ·Π²ΠΈΡΠΊΡ Π½Π° ΠΏΡΠΎΡΡΠ·Ρ ΡΠΎΠΊΡ ΠΏΠΎ Π΄Π°Π½ΠΈΠΌ ΠΎΠ±Π»Π°ΡΠ½ΠΎΡ Π΄ΠΈΡΡΡΠΎΡ ΠΏΠΎΠ»ΡΠΊΠ»ΡΠ½ΡΠΊΠΈ.
ΠΡΠΈ ΡΠΈΡΡΠ²Π°Π½Π½Ρ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°, Π²ΠΈΠΊΠΎΡΠΈΡΡΠΎΠ²ΡΠΉΡΠ΅ ΠΏΠΎΡΠΈΠ»Π°Π½Π½Ρ http://essuir.sumdu.edu.ua/handle/123456789/503
ΠΠΌΡΠ½ΠΈ Π³ΠΎΡΠΌΠΎΠ½ΠΎΠΏΡΠΎΠ΄ΡΠΊΡΡΡΠΎΡ ΡΡΠ½ΠΊΡΡΡ ΡΠ΅ΡΠΎΠΏΠ»Π°ΡΠ΅Π½ΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΡ ΠΏΡΠ΄ Π²ΠΏΠ»ΠΈΠ²ΠΎΠΌ ΡΠΊΡΠ΄Π»ΠΈΠ²ΠΈΡ ΠΏΡΠΎΠΌΠΈΡΠ»ΠΎΠ²ΠΈΡ ΡΠΈΠ½Π½ΠΈΠΊΡΠ²
More effective complex therapy for placental insufficiency in the deep study of hormonal productional functiol of FPC at pregnancy as a result of chronic intoxication of salts of heavy metals is under investigation.ΠΠΎΠΊΡΠ°ΡΠ°Π½Π½Ρ Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΡ ΡΠ΅ΡΠ°ΠΏΡΡ ΠΏΠ»Π°ΡΠ΅Π½ΡΠ°ΡΠ½ΠΎΡ Π΄ΠΈΡΡΡΠ½ΠΊΡΡΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Ρ Π³Π»ΠΈΠ±ΠΎΠΊΠΎΠ³ΠΎ Π²ΠΈΠ²ΡΠ΅Π½Π½Ρ Π³ΠΎΡΠΌΠΎΠ½ΠΎΠΏΡΠΎΠ΄ΡΠΊΡΡΡΠΎΡ ΡΡΠ½ΠΊΡΡΡ Π€ΠΠ Ρ Π²Π°Π³ΡΡΠ½ΠΈΡ
Π· Ρ
ΡΠΎΠ½ΡΡΠ½ΠΎΡ ΡΠ½ΡΠΎΠΊΡΠΈΠΊΠ°ΡΡΡΡ ΡΠΎΠ»ΡΠΌΠΈ Π²Π°ΠΆΠΊΠΈΡ
ΠΌΠ΅ΡΠ°Π»ΡΠ².
ΠΡΠΈ ΡΠΈΡΡΠ²Π°Π½Π½Ρ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°, Π²ΠΈΠΊΠΎΡΠΈΡΡΠΎΠ²ΡΠΉΡΠ΅ ΠΏΠΎΡΠΈΠ»Π°Π½Π½Ρ http://essuir.sumdu.edu.ua/handle/123456789/169
ΠΡΠ΄ΡΡΠΊΠΈΠΉ ΡΠΌΡΠ½ΠΎΠ³Π»ΠΎΠ±ΡΠ»ΡΠ½ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΌΡ Π»ΡΠΊΡΠ²Π°Π½Π½Ρ Π°Π½ΡΠΈΡΠΎΡΡΠΎΠ»ΡΠΏΡΠ΄Π½ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΡ
ΠΠ΅ΡΠ° Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ: ΠΎΡΡΠ½ΠΈΡΠΈ ΠΏΠ΅ΡΠ΅Π±ΡΠ³ Π²Π°Π³ΡΡΠ½ΠΎΡΡΡ ΠΉ ΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°Ρ Ρ Π²Π°Π³ΡΡΠ½ΠΈΡ
ΡΠ· ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π²ΡΡΠ°ΡΠΈ ΠΏΠ»ΠΎΠ΄Π° (Π‘ΠΠ), ΠΎΠ±ΡΠΌΠΎΠ²Π»Π΅Π½ΠΈΠΌ Π°Π½ΡΠΈΡΠΎΡΡΠΎΠ»ΡΠΏΡΠ΄Π½ΠΈΠΌ ΡΠΈΠ΄ΡΠΎΠΌΠΎΠΌ (ΠΠ€Π‘), Ρ Π΄ΠΈΠ½Π°ΠΌΡΡΡ Π»ΡΠΊΡΠ²Π°Π½Π½Ρ Π· Π·Π°ΡΡΠΎΡΡΠ²Π°Π½Π½ΡΠΌ Π»ΡΠ΄ΡΡΠΊΠΎΠ³ΠΎ ΡΠΌΡΠ½ΠΎΠ³Π»ΠΎΠ±ΡΠ»ΡΠ½Ρ β ΡΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΎ Π°ΠΊΡΠΈΠ²Π½ΠΎΡ Π±ΡΠ»ΠΊΠΎΠ²ΠΎΡ ΡΡΠ°ΠΊΡΡΡ ΡΠΌΡΠ½ΠΎΠ³Π»ΠΎΠ±ΡΠ»ΡΠ½Ρ G.
ΠΡΠΈ ΡΠΈΡΡΠ²Π°Π½Π½Ρ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°, Π²ΠΈΠΊΠΎΡΠΈΡΡΠΎΠ²ΡΠΉΡΠ΅ ΠΏΠΎΡΠΈΠ»Π°Π½Π½Ρ http://essuir.sumdu.edu.ua/handle/123456789/3646
Fetal infections optimization of pregnancy and delivery introduction
The aim: Improving perinatal outcomes in pregnant women at high risk of intrauterine infection by developing diagnostic criteria and algorithms for managing pregnancy and childbirth.
Materials and methods: The study of pregnancy and childbirth was conducted in 72 patients at high risk of IUI, which formed the main group. The control group consisted of
64 patients with a low infectious risk of IUI. Culture, bacterioscopic and biochemical methods were used to identify microorganisms. Peculiarities of infection in the examined
women were investigated by determining the concentration of Ig M and IgG in the blood serum and performed polymerase chain reaction for measles virus, cytomegalovirus, parvovirus B19. Serum for the presence of specific immune globulins to these pathogens was examined by ELISA. Comprehensive ultrasound examination in B-mode was performed to determine the feto metry of the fetus and assess its development with the determination of the estimated mass, location, size and structure of the placenta, the amount of
amniotic fluid. To determine the condition of the fetus, a Doppler study of blood flow in the uterine arteries, umbilical artery, middle cerebral artery of the fetus and venous duct.
Results: Analyzing the course of this pregnancy in women of the studied groups threatened miscarriage and the threat of premature birth occurred in 24 (33.3%) cases, with signs of isthmic-cervical insufficiency were diagnosed in 13 (18.1%) patients. In the control group of patients, the threat of abortion was diagnosed in 15 (23.4%) patients.
According to ultrasound examination, patients in the main group in 12 (16.7%) cases were diagnosed with fetal growth retardation, in 25 (34.7%) patients at high risk of IUI there were changes in the placenta, namely, hyper echogenic inclusions in the placenta occurred in 7 (9.7%) cases, dilation of the intervillous space in 8 (11.1%) cases, placental hyperplasia in 7 (9.7%) cases, polyhydramnios was diagnosed in only 5 (6), 9%) cases, with 1 (1.4%) acute polyhydramnios in patients with signs of acute respiratory viral
infection during pregnancy.
Conclusions: Women at high risk for IUI require close monitoring of the fetus due to the increased frequency of hemodynamic changes in uteroplacental-fetal circulation, including fetal-placental β 22.2% and the occurrence of intrauterine growth retardation.
Women with suspected cytomegalovirus infection require determination of seroconversion; in case of immunologically confirmed infection, it is desirable to recognize PCR for cytomegalovirus in the amniotic fluid in order to determine further management and monitoring of this pregnancy
ΠΡ ΠΎΠ³ΡΠ°ΡΡΡΠ½Ρ ΠΌΠ°ΡΠΊΠ΅ΡΠΈ Π½Π΅Π²ΠΈΠ½ΠΎΡΡΠ²Π°Π½Π½Ρ Π²Π°Π³ΡΡΠ½ΠΎΡΡΡ Ρ ΠΏΠ΅ΡΡΠΎΠΌΡ ΡΡΠΈΠΌΠ΅ΡΡΡΡ
Π‘Π΅ΡΠ΅Π΄ Π½Π°ΠΉΠ²Π°ΠΆΠ»ΠΈΠ²ΡΡΠΈΡ
ΠΏΡΠΎΠ±Π»Π΅ΠΌ ΠΏΡΠ°ΠΊΡΠΈΡΠ½ΠΎΠ³ΠΎ Π°ΠΊΡΡΠ΅ΡΡΡΠ²Π° ΠΎΠ΄Π½Π΅ Π· ΠΏΠ΅ΡΡΠΈΡ
ΠΌΡΡΡΡ Π·Π°ΠΉΠΌΠ°Ρ Π½Π΅Π²ΠΈΠ½ΠΎΡΡΠ²Π°Π½Π½Ρ Π²Π°Π³ΡΡΠ½ΠΎΡΡΡ Π² Π ΡΡΠΈΠΌΠ΅ΡΡΡΡ, ΡΠΎ Ρ ΠΎΠ΄Π½ΡΡΡ Π· ΠΎΡΠ½ΠΎΠ²Π½ΠΈΡ
ΠΏΡΠΈΡΠΈΠ½ ΠΏΠ΅ΡΠΈΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΡ Π·Π°Ρ
Π²ΠΎΡΡΠ²Π°Π½ΠΎΡΡΡ ΡΠ° ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΡ Ρ ΡΠΊΠ»Π°Π΄Π°Ρ 15 β 20% Π²ΡΠ΄ Π±Π°ΠΆΠ°Π½ΠΈΡ
Π²Π°Π³ΡΡΠ½ΠΎΡΡΠ΅ΠΉ.
ΠΡΠΈ ΡΠΈΡΡΠ²Π°Π½Π½Ρ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°, Π²ΠΈΠΊΠΎΡΠΈΡΡΠΎΠ²ΡΠΉΡΠ΅ ΠΏΠΎΡΠΈΠ»Π°Π½Π½Ρ http://essuir.sumdu.edu.ua/handle/123456789/3290