Alcohol use among adolescents in India: a systematic review

Abstract Background Alcohol use is typically established during adolescence and initiation of use at a young age poses risks for short- and long-term health and social outcomes. However, there is limited understanding of the onset, progression and impact of alcohol use among adolescents in India. The aim of this review is to synthesise the evidence about prevalence, patterns and correlates of alcohol use and alcohol use disorders in adolescents from India. Methods Systematic review was conducted using relevant online databases, grey literature and unpublished data/outcomes from subject experts. Inclusion and exclusion criteria were developed and applied to screening rounds. Titles and abstracts were screened by two independent reviewers for eligibility, and then full texts were assessed for inclusion. Narrative synthesis of the eligible studies was conducted. Results Fifty-five peer-reviewed papers and one report were eligible for inclusion in this review. Prevalence of ever or lifetime alcohol consumption ranged from 3.9% to 69.8%; and prevalence of alcohol consumption at least once in the past year ranged from 10.6% to 32.9%. The mean age for initiation of drinking ranged from 14.4 to 18.3 years. Some correlates associated with alcohol consumption included being male, older age, academic difficulties, parental use of alcohol or tobacco, non-contact sexual abuse and perpetuation of violence. Conclusion The evidence base for alcohol use among adolescents in India needs a deeper exploration. Despite gaps in the evidence base, this synthesis provides a reasonable understanding of alcohol use among adolescents in India and can provide direction to policymakers. </jats:sec

Fixed drug eruption related to sunitinib: a case report

Sunitinib is an oral multi-targeted tyrosine kinase inhibitor. It has been approved for the treatment of gastro-intestinal stromal tumor and advanced renal cell carcinoma. Fixed drug eruption related to sunitinib is a rare cutaneous adverse drug reaction

Transport, magnetic and thermal properties of La1−xPrxSr2Mn2O7

From resistivity specific heat (measured at B=0 and 9 T) and thermoelectric power measurements on La1−xPrxSr2Mn2O7, 00.7 between 120<T<160 K.© Elsevie

An efficient storage framework design for cloud computing: Deploying compression on de-duplicated No-SQL DB using HDFS

Cloud Computing is an alluring technology which provides elasticity, scalability and cost-efficiency over a network. In recent years, database obtrusion has become a crucial feature in cloud computing. Rapid data growth and need to keep it safer require organizations to integrate how they manage and use their data. To meet these necessities, No-SQL has proven to be better over RDBMS because of its high scalability. To provide better availability, No-SQL databases has a huge among of Redundant data. In order to address this neophyte challenges and further achieve a dependable and secure cloud storage service, different storage efficiency approaches are used these days. This paper proposed a novel design of efficient storage framework for cloud computing for No-SQL databases. The framework tackles the challenge of managing the huge amount of the data at the back end of the cloud service provider. The Framework uses Map-Reduce paradigm of Hadoop with the schema-less document-oriented MongoDB. The outcomes are improved storage efficiency by saving subsequent storage space and network bandwidth during data transfer among multiple nodes

Sahoo-Supplement Fig 2.pdf

<p><b>Micro-architectural parameters of iliac crest bone evaluated by µCT</b></p> <p>(a) 3-D µCT images showing a normal bone and gross micro-architectural deterioration in the proband’s bone, (b<b>)</b> All parameters of cortical bone microarchitecture; T.Ar (periosteal area), B.Ar (cortical mean cross-section area), Cs.Th (cortical thickness), T.Pm (periosteal perimeter), and B.Pm (cortical bone perimeter) are significantly lower in the proband compared to age and sex-matched healthy control,<b> </b>(c)<b> </b>Parameters of trabecular bone microarchitecture; Tb.Th (trabecular thickness), and Tb.N (trabecular number) are decreased, while Tb.Sp (trabecular separation) and SMI (structure model index) are increased in the proband’s bone. All values are expressed as mean ± S.E. </p> <p>* p<0.05 and ** p<0. 01versus control</p

Supplementary Data File- Hypophosphataemic osteomalacia in a patient with neurofibromatosis type 1- a role for FGF23?

<h2>Supplementary Data File</h2

Supplementary Data-Hypophosphataemic osteomalacia in a patient with neurofibromatosis type 1- a role for FGF23?

Supplementary Dat

Supplement Figures - Hypophosphataemic osteomalacia in a patient with neurofibromatosis type 1- a role for FGF23?

<p><b>Supplement Figure 1</b></p> <p><b><i>Family pedigree</i> </b><br> <b></b></p><p><br></p><p><br></p> <p><b>Supplement Figure 2</b></p> <p><b><i>Micro-architectural parameters of iliac crest bone evaluated by µCT</i></b></p> <p>(a) 3-D µCT images showing a normal bone and gross micro-architectural deterioration in the proband’s bone, (b<b>)</b> All parameters of cortical bone microarchitecture; T.Ar (periosteal area), B.Ar (cortical mean cross-section area), Cs.Th (cortical thickness), T.Pm (periosteal perimeter), and B.Pm (cortical bone perimeter) are significantly lower in the proband compared to age and sex-matched healthy control,<b> </b>(c)<b> </b>Parameters of trabecular bone microarchitecture; Tb.Th (trabecular thickness), and Tb.N (trabecular number) are decreased, while Tb.Sp (trabecular separation) and SMI (structure model index) are increased in the proband’s bone. All values are expressed as mean ± S.E. </p> <p>* p<0.05 and ** p<0. 01 versus control</p

Sahoo-Supplement Fig 1.Hypophosphataemic osteomalacia in a patient with neurofibromatosis type 1- a role for FGF23?

<b>Family pedigree </b