Requisas personales y violación a la dignidad e intimidad de las féminas visitantes, Chimbote

La presente tesis titulada “Requisas Personales y Violación a la dignidad e Intimidad de las Féminas visitantes. Chimbote” tiene como objetivo general: determinar si las requisas personales aplicadas a las féminas visitantes violan el derecho a la dignidad e intimidad personal en el Centro Penitenciario Cambio Puente, para ello, se han desarrollado los conceptos de Requisas personales, tipos de requisas, violación de derechos, derecho a la dignidad, derecho a la intimidad. Es un enfoque cualitativo porque surgen nuevas interrogantes en el proceso; es descriptivo porque se basa en describir un fenómeno particular a partir de la información obtenida; se fundamenta en el diseño de teorías; porque se nutre de aspectos jurídicos y lógicos argumentales. Porque se basa en la doctrina y jurisprudencia original y vigente. Es un tipo diseñado para la investigación cualitativa porque se utiliza para desarrollar teorías sobre fenómenos relevantes que se encuentran en la sociedad. Las técnicas de recogida de información han sido validadas por 3 expertos en derecho penal y procesal penal. Así se ha aplicado a 12 participantes seleccionados en base a sus conocimientos y experiencia, así tenemos: por 5 Fiscales del Distrito Fiscal del Santa, 4 trabajadores del INPE y 3 abogadas

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field