4 research outputs found
Enhanced Hsp70 Expression Protects against Acute Lung Injury by Modulating Apoptotic Pathways
The Acute respiratory distress syndrome (ARDS) is a highly lethal inflammatory lung disorder. Apoptosis plays a key role in its pathogenesis. We showed that an adenovirus expressing the 70 kDa heat shock protein Hsp70 (AdHSP) protected against sepsis-induced lung injury. In this study we tested the hypothesis that AdHSP attenuates apoptosis in sepsis-induced lung injury
IL-6 MODULATES SEPSIS-INDUCED DECREASES IN TRANSCRIPTION OF HEPATIC ORGANIC ANION AND BILE ACID TRANSPORTERS
Impaired Hepatocellular Regeneration in Murine Sepsis Is Dependent on Regulatory Protein Levels
Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC)
Targeted inhibition of δ-PKC exerted a lung-protective effect and significantly attenuated pulmonary inflammatory cell infiltration, disruption of lung architecture, and pulmonary edema associated with sepsis