High prevalence of overweight and obesity in adults with Crohn's disease: associations with disease and lifestyle factors.

peer-reviewedObesity and overweight are major public health issues. Although traditionally associated with weight loss, there is now evidence that increasing Body Mass Index (BMI) and overweight are emerging features of Crohn's disease (CD) and may be associated with more severe disease course. The aim of the study was to determine the prevalence of overweight and obesity in patients with CD compared with matched healthy controls and to identify disease-specific and generic factors associated with current BMI in this group.PUBLISHEDpeer-reviewe

Undernutrition in inactive and mildly active Crohn\u27s Disease : an unrecognised problem?

THESIS 9482Crohn\u27s disease (CD), the incidence of which is increasing worldwide, is a chronic transmural inflammatory disease that can affect any part of the gastrointestinal tract. It follows a relapsing remitting course and results in symptoms such as weight loss, diarrhoea and abdominal pain. Undernutrition is a common feature of active disease, with weight loss and malnutrition apparent during flare-ups and periods of high disease activity affecting up to 85% of patients. On the other hand, during disease remission or at times of low disease activity, undernutrition is not so apparent and can be difficult to diagnose as most patients in remission look and feel well and lack the typical signs normally associated with malnutrition. However, as subclinical inflammation and symptoms predisposing patients to undernutrition can persist, and treatments such as corticosteroids can add to the risk of undernutrition (as they cause muscle wasting and bone loss but can also lead to weight gain and redistribution of body fat); undernutrition can occur and remain un-noticed due to weight gain

High prevalence of overweight and obesity in adults with Crohn\u27s disease: associations with disease and lifestyle factors.

Obesity and overweight are major public health issues. Although traditionally associated with weight loss, there is now evidence that increasing Body Mass Index (BMI) and overweight are emerging features of Crohn\u27s disease (CD) and may be associated with more severe disease course. The aim of the study was to determine the prevalence of overweight and obesity in patients with CD compared with matched healthy controls and to identify disease-specific and generic factors associated with current BMI in this group.PUBLISHEDpeer-reviewe

High prevalence of overweight and obesity in adults with Crohn's disease: associations with disease and lifestyle factors.

Obesity and overweight are major public health issues. Although traditionally associated with weight loss, there is now evidence that increasing Body Mass Index (BMI) and overweight are emerging features of Crohn's disease (CD) and may be associated with more severe disease course. The aim of the study was to determine the prevalence of overweight and obesity in patients with CD compared with matched healthy controls and to identify disease-specific and generic factors associated with current BMI in this group