576 research outputs found

    Two-Dimensional Controlled Syntheses of Polypeptide Molecular Brushes via N-Carboxyanhydride Ring-Opening Polymerization and Ring-Opening Metathesis Polymerization.

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    Well-defined molecular brushes bearing polypeptides as side chains were prepared by a "grafting through" synthetic strategy with two-dimensional control over the brush molecular architectures. By integrating N-carboxyanhydride ring-opening polymerizations (NCA ROPs) and ring-opening metathesis polymerizations (ROMPs), desirable segment lengths of polypeptide side chains and polynorbornene brush backbones were independently constructed in controlled manners. The N2 flow accelerated NCA ROP was utilized to prepare polypeptide macromonomers with different lengths initiated from a norbornene-based primary amine, and those macromonomers were then polymerized via ROMP. It was found that a mixture of dichloromethane and an ionic liquid were required as the solvent system to allow for construction of molecular brush polymers having densely-grafted peptide chains emanating from a polynorbornene backbone, poly(norbornene-graft-poly(β-benzyl-l-aspartate)) (P(NB-g-PBLA)). Highly efficient postpolymerization modification was achieved by aminolysis of PBLA side chains for facile installment of functional moieties onto the molecular brushes

    A SOCIAL SURVEY ON COMMUNITY RESPONSE TO ROAD TRAFFIC NOISE IN HANOI

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    Joint Research on Environmental Science and Technology for the Eart

    Innovative in silico approaches to address avian flu using grid technology

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    The recent years have seen the emergence of diseases which have spread very quickly all around the world either through human travels like SARS or animal migration like avian flu. Among the biggest challenges raised by infectious emerging diseases, one is related to the constant mutation of the viruses which turns them into continuously moving targets for drug and vaccine discovery. Another challenge is related to the early detection and surveillance of the diseases as new cases can appear just anywhere due to the globalization of exchanges and the circulation of people and animals around the earth, as recently demonstrated by the avian flu epidemics. For 3 years now, a collaboration of teams in Europe and Asia has been exploring some innovative in silico approaches to better tackle avian flu taking advantage of the very large computing resources available on international grid infrastructures. Grids were used to study the impact of mutations on the effectiveness of existing drugs against H5N1 and to find potentially new leads active on mutated strains. Grids allow also the integration of distributed data in a completely secured way. The paper presents how we are currently exploring how to integrate the existing data sources towards a global surveillance network for molecular epidemiology.Comment: 7 pages, submitted to Infectious Disorders - Drug Target

    Biodiversity of Tintinnids (Tintinnida) in Khanh Hoa - Binh Thuan waters

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    Tintinnidsarean important protozoan group in the aquatic food web and had been widely studied in various waters. There are about 1000 known species in the world. However, there have beenvery few taxonomic studies in Vietnam and therefore the number of Tintinnid taxa and their distribution are poorly known. Thepresent study documents 65 tintinnids species belonging to 30 genera and 13 families in samples collected from Khanh Hoa - Binh Thuan waters in 2016 and 2017. There were 17 new taxa records for Vietnam protozoan fauna, raising the number of tintinnids recorded in Vietnam to 125 taxa. Tintinnid assemblages in Khanh Hoa-Binh Thuan waters shared about 17 species with Ha Long Bay, 32 species with Con Co island and 26 species with coastal waters of South Vietnam. Analysis of species diversity shows that the Shannon diversity index H' varied from 1.5 to 2.6. Distribution of species numbers and diversity in the Khanh Hoa - Binh Thuan waters revealed possible combined effects of hydrographical activities (e.g. upwelling), Mekong river influent (e.g. salinity), and food available on tintinnid communities.   Citation: Nguyen Thi Kieu, Phan Tan Luom, Nguyen Tam Vinh, Nguyen Ngoc Lam, Josepth P. Montoya, Doan Nhu Hai, 2017. Biodiversity of Tintinnids (Tintinnida) in Khanh Hoa - Binh Thuan waters. Tap chi Sinh hoc, 39(4): 421-433. DOI: 10.15625/0866-7160/v39n4.11033. *Corresponding author:[email protected] Received 19 September 2017, accepted 12 December 2017

    High Energy Scattering in the Quasi-Potential Approach

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    Asymptotic behavior of the scattering amplitude for two scalar particles by scalar, vector and tensor exchanges at high energy and fixed momentum transfers is reconsidered in quantum field theory. In the framework of the quasi-potential approach and the modified perturbation theory a systematic scheme of finding the leading eikonal scattering amplitudes and its corrections are developed and constructed.The connection between the solutions obtained by quasi-potential and functional approaches is also discussed.The first correction to leading eikonal amplitude is found. Keywords: Eikonal scattering theory, Quantum gravity.Comment: 18 pages. arXiv admin note: substantial text overlap with arXiv:0804.343

    Challenges to Accurate Estimation of Methane Emission from Septic Tanks with Long Emptying Intervals

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    Septic tanks in low- and middle-income countries are often not emptied for a long time, potentially resulting in poor pollutant removal efficiency and increased greenhouse gas emissions, including methane (CH₄). We examined the impact of long emptying intervals (4.0–23 years) on the biochemical oxygen demand (BOD) removal efficiency of 15 blackwater septic tanks and the CH₄ emission rates of 23 blackwater septic tanks in Hanoi. The average BOD removal efficiency was 37% (−2–65%), and the average CH₄ emission rate was 10.9 (2.2–26.8) g/(cap·d). The emptying intervals were strongly negatively correlated with BOD removal efficiency (R = −0.676, p = 0.006) and positively correlated with CH₄ emission rates (R = 0.614, p = 0.001). CH₄ emission rates were positively correlated with sludge depth (R = 0.596, p = 0.002), but against expectation, negatively correlated with BOD removal efficiency (R = −0.219, p = 0.451). These results suggest that shortening the emptying interval improves the BOD removal efficiency and reduces the CH₄ emission rate. Moreover, the CH₄ emission estimation of the Intergovernmental Panel on Climate Change, which is a positive conversion of BOD removal, might be inaccurate for septic tanks with long emptying intervals. Our findings suggest that emptying intervals, sludge depth, and per-capita emission factors reflecting long emptying intervals are potential parameters for accurately estimating CH₄ emissions from septic tanks

    Optical Propagation and Communication

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    Contains reports on four research projects.National Science Foundation (Grant ECS81-20637)U.S. Navy - Office of Naval Research (Contract N00014-81-K-0662)U.S. Army Research Office - Durham (Contract DAAG29-80-K-0022)U.S. Navy - Office of Naval Research (Contract N00014-80-C-0941
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