REQUIREMENTS IN THE PROCESS OF BUILDING A CONTINGENT OF ETHNIC MINORITY CADRES IN THE MOUNTAINOUS AREAS OF NGHE AN PROVINCE, VIETNAM

Nghe An is a province in Vietnam, with 10 mountainous districts and 1 mountainous town, accounting for 83.31% of the province's natural area. The mountainous area of Nghe An is a place with complicated and dangerous terrain and poor infrastructure; the lowest human development index (HDI) in the province; economic situation is extremely difficult, but it is a place with an important strategic position in terms of socio-economic development and protection of national border security. Therefore, building a contingent of ethnic minority cadres has a very important position and role in the development of the mountainous area of Nghe An. However, the work of building a contingent of ethnic minority cadres in mountainous districts of Nghe An currently has many shortcomings and limitations that need to be overcome, and possible solutions are needed so that the construction building a contingent of ethnic minority cadres in mountainous areas to achieve good results in the coming time.  Article visualizations

QUALITY OF PERSONNEL ETHNIC MINORITY IN THE MOUNTAIN AREA OF VIETNAM IN THE TIME OF PROMOTING INDUSTRIAL, MODERNIZING THE COUNTRY

Human resources are the most significant asset, a decisive factor for the existence and development of every country. Human resource development has become an urgent task not only of each country but also of each region and region according to the characteristics of geography, population and requirements of economic development orientation - society. In the mountainous areas of Vietnam, ethnic minority human resources are considered a central factor, playing a decisive role in socio-economic growth and development. Human resource training is a fundamental factor determining socio-economic development in ethnic minority areas in mountainous areas; it plays a decisive role in the education, professional and technical qualifications of human resources, training people capable of leading and gathering ethnic minority communities in production organization and social management; create human resources capable of applying new scientific and technological achievements in parallel with promoting indigenous knowledge and experiences of ethnic minorities in socio-economic development, and at the same time capable of solving new problems, problems arising in practice, production and social life.  Article visualizations

Genome Sequence of a Virulent African Swine Fever Virus Isolated in 2020 from a Domestic Pig in Northern Vietnam

This study reports the genome sequence of an isolated African swine fever (ASF) virus (VNUA-ASFV-05L1/HaNam) obtained at the fourth passage on pulmonary alveolar macrophages. The virus was isolated during a typical acute ASF outbreak in pigs in a northern province of Vietnam in 2020

Synthesis and biological evaluation of shikimic acid derivatives

From shikimic acid, new series of oseltamivir analogues containing either ether sulfur or ether oxygen at C-3 position were prepared and evaluated for their biological activities. This is the first report on synthesis of oseltamivir analogues with ether sulfur at C-3. Except for compounds 4d, 4f, 7c and 7d, the remaining compounds were found to be active against MCF-7, LU-1 and KB cell lines. As oseltamivir had no cytotoxicity against different cell lines such as MCF-7, LU-1, KB, MDCK, MRC-5, VERO, MK and 293, the modification of alkyl groups at C-3 of the oseltamivir ring framework could significantly increase the cytotoxicity for this class of compounds. Loss of neuraminidase inhibition activity of these synthetic oseltamivir analogues suggested that the alkyl ether groups at C-3 should be critical for their anti-neuraminidase activity

Eupolauridine alkaloids of Polyalthia nemoralis

Two eupolauridine alkaloids, eupolauridine (1) and 8-methoxyeupolauridine (2), together with a phenanthrene compound, 2,7-dihydroxy-3,6-dimethoxyphenanthrene (3), were isolated from the ethyl acetate extract of Polyalthia nemoralis barks. Their structures were elucidated on the basis of spectroscopic analysis and comparison with related known compounds. These compounds were evaluated the cytotoxicity on seven human cancer cell lines including KB, MCF7, LU-1, HepG2, LNCap, SW626 and SW480

Synthesis of antiulcer drug esomeprazole.

Esomeprazole (Nexium®), the (S)-isomer of Omeprazole, is the first proton-pump inhibitor developed as a single isomer for the treatment of acid-related diseases. It is used for the treatment of peptic ulcers, gastroesophagal reflux disease, and erosive esophagitis. Herein, we report our synthetic study of esomeprazole sodium salt from the starting    2-mercapto-5-methoxybenzimidazole and 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride reagents. The Esomeprazole sodium salt was obtained from enantioselectivesulfoxidation reaction in moderate yield with high enantioselectivity

The role of eco-innovation, eco-investing, and green bonds in achieving sustainable economic development: evidence from Vietnam

The perpetual upsurge of global economic development and human actions has multiplied the intensity of carbon emissions that signifies the effectiveness eco-innovation, eco-investment and green bonds in order to curb carbon emissions. Thereby, the study attempts to examine the impact of eco-innovation, eco-investment, and green bonds on the achievement of sustainable economic development (S.E.D.) in Vietnamese economy. Secondary data was used and extracted from Organization for Economic Co-operation and Development (O.E.C.D.), central bank, and World Development Indicators (W.D.I.) from 1991 to 2020. Techniques such as dynamic Auto-regressive Distributed Lags (D.A.R.D.L.) model and Bayesian Auto-regressive Distributed Lags (B.A.R.D.L.) were employed to evaluate the relationship. Findings echo that that eco-innovation, eco-investment, green bonds, industrialisation, inflation, and employment rate share positive connection with the achievement of S.E.D. in Vietnam. The study guides the policymaking authorities that they should establish the policies related to S.E.D. by using eco-innovation and eco-investment

A practical synthesis of fluoroquinolone antibiotic moxifloxacin

The fluoroquinoloneantibiotic has been used in clinical practice since the 1980s, primarily for the treatment infections caused by Gram-negative bacteria. Moxifloxacin, a fourth-generation fluoroquinolone antibiotic developed by pharmaceutical company Bayer AG, exhibit broad spectrum of activity against Gram-negative, Gram-positive bacteria as well as  anaerobia. Moxifloxacin is used for community-acquired respiratory tract infections, sinusitis, acute exacerbations of chronic bronchitis and pneumonia, and skin structure infections. We have described the synthesis of moxifloxacin using difluoroboron complex. In this paper, a practical synthesis of moxifloxacin using acetoxyboronate complexwas reported

Lignans isolated from the ethyl acetate extract of Knema pachycarpa fruit

Knema is a genus of tropical evergreen trees of the family Myristicaceae found in South East Asian countries such as Vietnam, Thailand, and Malaysia. In this paper, four lignans, (+)-pinoresinol (1),(+) epi-pinoresinol (2), piperitol (3), and pluviatilol (4), were isolated from the ethyl acetate extract of the fruit of Knema pachycarpa, an indigenus tree in Vietnam. The chemical structures were determined by spectroscopic data and comparison with the reported literature. These compounds were isolated from Knema genus for the first time. Keywords. Knema pachycarpa de Wilde, (+)-Pinoresinol, (+)-Epi-pinoresinol, Piperitol, Pluviatilol