52,276 research outputs found

    Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues

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    We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique. Tissues of three human subjects, obtained at autopsy, were analyzed. BNP transcripts could be detected in the central nervous system, lung, thyroid, adrenal, kidney, spleen, small intestine, ovary, uterus, and striated muscle. ANP transcripts could also be demonstrated in various human extracardiac tissues including several endocrine organs. In all peripheral tissues, the level of both natriuretic peptide transcripts was approximately 1-2 orders of magnitude lower than in cardiac ventricular tissues. This distribution is in marked contrast to the much lower level of ANP and BNP transcripts present in extracardiac rat tissues (generally less than 1/1000 of ventricles). These data suggest differential expression of the two natriuretic peptide genes in cardiac and extracardiac tissues in man. Furthermore, the presence of local synthesis of ANP and BNP in various peripheral organs suggests paracrine and/or autocrine function of these natriuretic peptides

    Bound states and extended states around a single vortex in the d-wave superconductors

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    Making use of the Bogoliubov-de Gennes equation for the d-wave superconductors, we investigate the quasi-particle spectrum around a single vortex. Taking pFξ=10p_F\xi=10, we found that there are bound states which are localized around the vortex core, and extended states which are rather uniform, for E<Δ|E|<\Delta where EE is the quasi-particle energy and Δ\Delta is the asymptotic value of the order parameter for away from the vortex.Comment: 4 pages, 6 figure

    Strong disorder renormalization group on fractal lattices: Heisenberg models and magnetoresistive effects in tight binding models

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    We use a numerical implementation of the strong disorder renormalization group (RG) method to study the low-energy fixed points of random Heisenberg and tight-binding models on different types of fractal lattices. For the Heisenberg model new types of infinite disorder and strong disorder fixed points are found. For the tight-binding model we add an orbital magnetic field and use both diagonal and off-diagonal disorder. For this model besides the gap spectra we study also the fraction of frozen sites, the correlation function, the persistent current and the two-terminal current. The lattices with an even number of sites around each elementary plaquette show a dominant ϕ0=h/e\phi_0=h/e periodicity. The lattices with an odd number of sites around each elementary plaquette show a dominant ϕ0/2\phi_0/2 periodicity at vanishing diagonal disorder, with a positive weak localization-like magnetoconductance at infinite disorder fixed points. The magnetoconductance with both diagonal and off-diagonal disorder depends on the symmetry of the distribution of on-site energies.Comment: 19 pages, 20 figure

    A new root-knot nematode, Meloidogyne moensi n. sp. (Nematoda : Meloidogynidae), parasitizing Robusta coffee from Western Highlands, Vietnam

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    A new root-knot nematode, parasitizing Robusta coffee in Dak Lak Province, Western Highlands of Vietnam, is described as Meloidogyne moensi n. sp. Morphological and molecular analyses demonstrated that this species differs clearly from other previously described root-knot nematodes. Morphologically, the new species is characterized by a swollen body of females with a small posterior protuberance that elongated from ovoid to saccate; perineal patterns with smooth striae, continuous and low dorsal arch; lateral lines marked as a faint space or linear depression at junction of the dorsal and ventral striate; distinct phasmids; perivulval region free of striae; visible and wide tail terminus surrounding by concentric circles of striae; medial lips of females in dumbbell-shaped and slightly raised above lateral lips; female stylet is normally straight with posteriorly sloping stylet knobs; lip region of second stage juvenile (J2) is not annulated; medial lips and labial disc of J2 formed dumbbell shape; lateral lips are large and triangular; tail of J2 is conoid with rounded unstriated tail tip; distinct phasmids and hyaline; dilated rectum. Meloidogyne moensi n. sp. is most similar to M. africana, M. ottersoni by prominent posterior protuberance. Results of molecular analysis of rDNA sequences including the D2-D3 expansion regions of 28S rDNA, COI, and partial COII/16S rRNA of mitochondrial DNA support for the new species status

    Controllability and controller-observer design for a class of linear time-varying systems

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    “The final publication is available at Springer via http://dx.doi.org/10.1007/s10852-012-9212-6"In this paper a class of linear time-varying control systems is considered. The time variation consists of a scalar time-varying coefficient multiplying the state matrix of an otherwise time-invariant system. Under very weak assumptions of this coefficient, we show that the controllability can be assessed by an algebraic rank condition, Kalman canonical decomposition is possible, and we give a method for designing a linear state-feedback controller and Luenberger observer

    Control-system techniques for improved departure/spin resistance for fighter aircraft

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    Some fundamental information on control system effects on controllability of highly maneuverable aircraft at high angles of attack are summarized as well as techniques for enhancing fighter aircraft departure/spin resistance using control system design. The discussion includes: (1) a brief review of pertinent high angle of attack phenomena including aerodynamics, inertia coupling, and kinematic coupling; (2) effects of conventional stability augmentation systems at high angles of attack; (3) high angle of attack control system concepts designed to enhance departure/spin resistance; and (4) the outlook for applications of these concepts to future fighters, particularly those designs which incorporate relaxed static stability

    Applied analytical combustion/emissions research at the NASA Lewis Research Center

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    Emissions of pollutants from future commercial transports are a significant concern. As a result, the Lewis Research Center (LeRC) is investigating various low emission combustor technologies. As part of this effort, a combustor analysis code development program was pursued to guide the combustor design process, to identify concepts having the greatest promise, and to optimize them at the lowest cost in the minimum time
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