10 research outputs found
Transparency of Land-based Investments: Cameroon Country Snapshot
Despite a recent transparency law and participation in transparency initiatives, Cameroon’s investment environment remains plagued by poor transparency.
In a new report focusing on agribusiness projects in Cameroon, CCSI and the Centre pour l’Environnement et le Développement (CED) find that: Communities continue to be excluded from decision-making around investments. The government pursues a top-down approach to concession allocation and remains reluctant to recognize all legitimate tenure rights. The government faces threats to its legitimacy as the grievances of citizens and investors alike lead to the barring of roads by communities and investor withdrawals.
CCSI and CED therefore call for: A new law concerning the governance of land and land-based investment in Cameroon, to be developed in close consultation and collaboration with communities, Indigenous groups, and other actors. The law should respond to the transparency needs of affected communities, enable increased funding for technical support to communities, and facilitate the recognition of all legitimate customary land rights, with specific attention to Indigenous communities and women and girls. A national moratorium on any new approvals for large-scale agribusiness and other land-based investment projects until Cameroon’s legal and policy landscape has been reformed.
This research forms part of a broader portfolio of research conducted by CCSI on a demand-driven approach to land investment transparency, focusing on the transparency needs of project-affected communities and host governments. This project was funded with UK aid from the UK government; however, the views expressed do not necessarily reflect the UK government’s official policies
Legal empowerment for accountable, just and equitable governance of land and investment in Cameroon
Between 2018 and 2021, local and indigenous communities of the Ocean Division received legal support towards a more equitable and inclusive land governance... The lessons learned in the field have improved the recognition of their land rights and a set of recommendations to provided ongoing land reform in Cameroon
Xeno-monitoring of molecular drivers of artemisinin and partner drug resistance in P. falciparum populations in malaria vectors across Cameroon
Background: Monitoring of drug resistance in Plasmodium populations is crucial for malaria control. This has primarily been performed in humans and rarely in mosquitoes where parasites genetic recombination occurs. Here, we characterized the Plasmodium spp populations in wild Anopheles vectors by analyzing the genetic diversity of the P. falciparum kelch13 and mdr1 gene fragments implicated in artemisinin and partner drug resistance across Cameroon in three major malaria vectors.
Methods: Anopheles mosquitoes were collected across nine localities in Cameroon and dissected into the head/thorax (H/T) and abdomen (Abd) after species identification. A TaqMan assay was performed to detect Plasmodium infection. Fragments of the Kelch 13 and mdr1 genes were amplified in P. falciparum positive samples and directly sequenced to assess their drug resistance polymorphisms and genetic diversity profile.
Results: The study revealed a high Plasmodium infection rate in the major Anopheles vectors across Cameroon. Notably, An. funestus vector recorded the highest sporozoite (8.0%) and oocyst (14.4%) infection rates. A high P. falciparum sporozoite rate (80.08%) alongside epidemiological signatures of significant P. malariae (15.9%) circulation were recorded in these vectors. Low genetic diversity with six (A578S, R575I, G450R, L663L, G453D, N458D) and eight (H53H, V62L, V77E, N86Y, G102G, L132I, H143H, Y184F) point mutations were observed in the k13 and mdr1 backbones respectively. Remarkably, the R575I (4.4%) k13 and Y184F (64.2%) mdr1 mutations were the predominant variants in the P. falciparum populations.
Conclusion: The emerging signal of the R575I polymorphism in the Pfk13 propeller backbone entails the regular surveillance of molecular markers to inform evidence-based policy decisions. Moreover, the high frequency of the 86N184F allele highlights concerns on the plausible decline in efficacy of artemisinin-combination therapies (ACTs); further implying that parasite genotyping from mosquitoes can provide a more relevant scale for quantifying resistance epidemiology in the field
Epidemiology of malaria, schistosomiasis, and geohelminthiasis amongst children 3–15 years of age during the dry season in Northern Cameroon
Background:
The double burden of malaria and helminthiasis in children poses an obvious public health challenge, particularly in terms of anemia morbidity. While both diseases frequently geographically overlap, most studies focus on mono-infection and general prevalence surveys without molecular analysis. The current study investigated the epidemiological determinants of malaria, schistosomiasis, and geohelminthiasis transmission among children in the North Region of Cameroon.
Methodology:
School and pre-school children aged 3–15 year-of-age were enrolled from three communities in March 2021 using a community cross-sectional design. Capillary-blood samples were obtained, and each was examined for malaria parasites using rapid-diagnostic-test (RDT), microscopy, and PCR while hemoglobin level was measured using a hemoglobinometer. Stool samples were analyzed for Schistosoma mansoni, S. guineensis, and soil-transmitted-helminthiasis (STH) infections using the Kato Katz method, and urine samples were assessed for the presence of S. haematobium eggs (including hybrids) using the standard urine filtration technique.
Result:
A malaria prevalence of 56% (277/495) was recorded by PCR as opposed to 31.5% (156/495) by microscopy and 37.8% (186/495) by RDT. Similarly, schistosomiasis was observed at prevalence levels of up to 13.3% (66/495) overall [S. haematobium (8.7%); S. mansoni (3.8%); mixed Sh/Sm (0.6%); mixed Sh/Sm/Sg (0.2%). Both infections were higher in males and the 3–9 year-of-age groups. A high frequency of PCR reported P. falciparum mono-infection of 81.9% (227/277) and mixed P. falciparum/P. malariae infection of 17.3% (48/277) was observed. Malaria-helminths co-infections were observed at 13.1% (65/495) with marked variation between P. falciparum/S. haematobium (50.8%, 33/65); P. falciparum/S. mansoni (16.9%, 11/65) and P. falciparum/Ascaris (9.2%, 6/65) (χ2 = 17.5, p = 0.00003). Anemia prevalence was 32.9% (163/495), categorically associated with P. falciparum (45.8%, 104/227), Pf/Sh (11.5%, 26/227), and Pf/Sm (3.9%, 9/227) polyparasitism.
Conclusion:
Polyparasitism with malaria and helminth infections is common in school-aged children despite periodic long-lasting insecticide-treated nets (LLINs) distribution and regular school-based praziquantel (for schistosomiasis) and albendazole (for STH) campaigns. Co-existence of Plasmodium parasites and helminths infections notably Schistosoma species among children may concurrently lead to an increase in Plasmodium infection with an enhanced risk of anemia, highlighting the necessity of an integrated approach for disease control interventions
AMÉLIORER LE SYSTÈME D'EXPROPRIATION ET DE COMPENSATION DANS UN CONTEXTE DE PLURALISME JURIDIQUE: LEÇONS DU CAMEROU
Cameroon is currently witnessing an unprecedented wave of land-based investments, ranging from natural resources exploitation (oil, mining and gas), logging, large infrastructure building, etc. These developments happen in a context of population growth, in an increase in the domestic demand for land. There is a gap between the legislation governing expropriation and compensation in the country, and the variety of customary rules on land and resources. This context of legal pluralism results into endless conflicts opposing communities and the investors, including the State. A thorough analysis of the legislation reveals a series of weaknesses, and the on-going land reform in Cameroon offers a unique opportunity for an in-depth revision of the rules governing expropriation, in order to ensure a better protection of communities’ rights. This study indicated paths for the reform, in terms of improvements of the quality of information granted to potentially affected communities, in the composition and mandate of the commission identifying the victims and damages, and in the scope of compensation and modalities of payment