Demographic characteristics of the study population.

<p>Demographic characteristics of the study population.</p

Mean complement activities and concentrations in chronic central serous chorioretinopathy (CSC) patients and controls.

<p>Mean complement activities and concentrations in chronic central serous chorioretinopathy (CSC) patients and controls.</p

Additional file 1: of Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis

Table S1. Expression levels of key immune genes in mice with chronic relapsing EAE showing mild or severe neurological disability and comparison with mice showing no disability. Table S2. Mouse primer sequences. Table S3. Primary antibodies, dilution, source. Table S4. Log fold change values of NLRP3 inflammasome genes in the mouse spinal cord at the relapse of chronic relapsing EAE. (PDF 215 kb

Additional file 2: of Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis

Figure S1. Systemic administration of C6 antisense knocks down C6 in mice. Figure S2. QPCR determination of key components of the inflammasome pathway. Figure S3. PMX205 concentrations in plasma, brain and spinal cord. Figure S4. Systemic administration of C6 antisense prevents inflammation in the spinal cord of the chronic relapsing EAE model. Figure S5. C9 is localized at synapses. Figure S6. Systemic administration of C6 antisense prevents NLRP3 inflammasome expression in the spinal cord of the chronic relapsing EAE model. (PDF 877 kb