108 research outputs found
A SOCIO-COGNITIVE BASIS FOR STRATEGIC GROUPS: COGNITIVE DISSONANCE IN SWINE GENETICS
Institutional and Behavioral Economics, Livestock Production/Industries,
Toward Better Defining the Field of Agribusiness Management
Agribusiness management, authority, bounded rationality, diversified growth, resources., Agribusiness, Resource /Energy Economics and Policy, Q1,
Valuing Strategic Alliances in the Pharmaceutical/Biotechnology Industry
In an era of rapid and changing technological advances, a firm's survival and growth depends on its' ability to introduce products to the market. Since a firm's growth and survival depends on its' ability to develop products and services over time (Penrose, 1959), the question posed by this study is what determines a firm's ability to introduce products to market? In this study, a firm's ability to introduce product to markets are influenced by its' "absorptive capacity" to identify and internalize the resource benefits of its' alliance partners. Such an integrated view is absent in firm level and strategic alliance studies of product development. A conceptual model of firm product introductions is developed and empirically tested. Results generally support the hypotheses of this study.Research and Development/Tech Change/Emerging Technologies,
Learning to Learn: A Case for the Heterogeneous Expectations Hypothesis in Industrialized Markets
A cobweb model is developed where the heterogeneous expectation hypothesis is examined. An agent’s heterogeneous expectation involves the development of a “higher ordered learning” process in which agents over time develop expectations that are consistent with rational expectations. In addition, as cob web models are production based systems, an agents’ heterogeneous expectations are influenced by a specialization of activities. The case of the industrialization of the U.S. hog-pork industry is used to illustrate the influence of these features on the equilibrium and non-equilibrium properties of a modified cob-web model
A COEVOLUTIONARY APPROACH TO UNDERSTANDING THE PARADOX OF SOCIAL PRESSURES VERSUS ECONOMIC EFFICIENCY ACROSS THE WORLD'S FOOD CHAINS
Institutional and Behavioral Economics,
INCENTIVE INCOMPATIBILITY IN CO-OPERATIVE AGRIBUSINESS FIRMS IN CANADA: DOES SUPPLY MANAGEMENT MATTER?
Agribusiness,
A developmental approach to diversifying neuroscience through effective mentorship practices: perspectives on cross-identity mentorship and a critical call to action.
Many early-career neuroscientists with diverse identities may not have mentors who are more advanced in the neuroscience pipeline and have a congruent identity due to historic biases, laws, and policies impacting access to education. Cross-identity mentoring relationships pose challenges and power imbalances that impact the retention of diverse early career neuroscientists, but also hold the potential for a mutually enriching and collaborative relationship that fosters the mentee\u27s success. Additionally, the barriers faced by diverse mentees and their mentorship needs may evolve with career progression and require developmental considerations. This article provides perspectives on factors that impact cross-identity mentorship from individuals participating in Diversifying the Community of Neuroscience (CNS)-a longitudinal, National Institute of Neurological Disorders and Stroke (NINDS) R25 neuroscience mentorship program developed to increase diversity in the neurosciences. Participants in Diversifying CNS were comprised of 14 graduate students, postdoctoral fellows, and early career faculty who completed an online qualitative survey on cross-identity mentorship practices that impact their experience in neuroscience fields. Qualitative survey data were analyzed using inductive thematic analysis and resulted in four themes across career levels: (1) approach to mentorship and interpersonal dynamics, (2) allyship and management of power imbalance, (3) academic sponsorship, and (4) institutional barriers impacting navigation of academia. These themes, along with identified mentorship needs by developmental stage, provide insights mentors can use to better support the success of their mentees with diverse intersectional identities. As highlighted in our discussion, a mentor\u27s awareness of systemic barriers along with active allyship are foundational for their role
LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
Tumor-associated macrophages (TAMs) are a heterogeneous population of cells that facilitate cancer progression. However, our knowledge of the niches of individual TAM subsets and their development and function remain incomplete. Here, we describe a population of lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1)-expressing TAMs, which form coordinated multi-cellular “nest” structures that are heterogeneously distributed proximal to vasculature in tumors of a spontaneous murine model of breast cancer. We demonstrate that LYVE-1+ TAMs develop in response to IL-6, which induces their expression of the immune-suppressive enzyme heme oxygenase-1 and promotes a CCR5-dependent signaling axis, which guides their nest formation. Blocking the development of LYVE-1+ TAMs or their nest structures, using gene-targeted mice, results in an increase in CD8+ T cell recruitment to the tumor and enhanced response to chemotherapy. This study highlights an unappreciated collaboration of a TAM subset to form a coordinated niche linked to immune exclusion and resistance to anti-cancer therapy
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