769 research outputs found

    University Biology patrons in the library literature 2000-2010: A Content Analysis & Literature Review

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    The researcher conducted a content analysis and literature review of papers written from 2000-2010 that focused on university biology students, faculty, and their papers. Scholarly articles were divided into the library research domains. The largest number of papers was from the Education domain, followed closely by Collections. Only two papers were categorized as Reference/Enquiries, and no papers were found in Management and Professional Issues. This research will enable science librarians to better understand what has already been written about biology subjects in a university setting. Gaps in the literature can help other librarians who are interested in pursuing more research with biology subjects

    Grey and white matter differences in Chronic Fatigue Syndrome : A voxel-based morphometry study

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    Conflicts of interest and source of funding The authors declare no conflicts of interest. This research was funded by the Medical Research Council (MR/J002712/1). AF is supported by Research Capability Funding from the Newcastle upon Tyne Hospitals NHS Foundation Trust and the Northumberland, Tyne and Wear NHS Foundation Trust.Peer reviewedPublisher PD

    New probes for heme detection in biological systems

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    Non-destructive methods to assess health of wild tropical frogs (túngara frogs: <i>Engystomops pustulosus</i>) in Trinidad reveal negative impacts of agricultural land

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    Amphibians are threatened globally with at least 43% of species declining and the most important stressor being habitat loss or degradation. Amphibians inhabiting highly biodiverse tropical regions are disproportionately threatened; however, the effects of landscape alterations on amphibian health are virtually unknown. In this study, we utilised non-destructive techniques to compare size (weight, snout-vent length [SVL]), body condition, male secondary sexual features (forelimb width, nuptial pad length) and breeding success (egg number, fertility [percentage fertilised eggs], hatching success) in túngara frogs (Engystomops pustulosus) collected from reference (n = 5), suburban (n = 6) and agricultural (n = 4) sites in Trinidad; characterised by presence/absence of crops/houses. All measured endpoints were negatively impacted in frogs collected from agricultural sites. The largest effect was observed for hatching success (2.77-fold lower) and egg number (2.5-fold lower). Less pronounced effects were observed on male frogs (weight: 1.77-fold lower; SVL: 1.18-fold lower; forelimb width: 1.33-fold lower; nuptial pad length: 1.15-fold lower). Our findings demonstrate negative impacts of agricultural sites on túngara frog health, with the number of viable offspring reduced by almost one third. The methods outlined here are technically simple and low-cost and thereby have potential for application to other species in order to investigate the potential impacts of habitat degradation on amphibian health. Furthermore, as these methods are non-destructive, they could be used to investigate the potential contribution of frog size and/or reproductive capability as a causative factor contributing to population declines in threatened species, which is particularly pressing in tropical regions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11356-022-20105-4

    A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses

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    Background: Thoroughbred racehorses are subject to non-traumatic distal limb bone fractures that occur during racing and exercise. Susceptibility to fracture may be due to underlying disturbances in bone metabolism which have a genetic cause. Fracture risk has been shown to be heritable in several species but this study is the first genetic analysis of fracture risk in the horse. Results: Fracture cases (n = 269) were horses that sustained catastrophic distal limb fractures while racing on UK racecourses, necessitating euthanasia. Control horses (n = 253) were over 4 years of age, were racing during the same time period as the cases, and had no history of fracture at the time the study was carried out. The horses sampled were bred for both flat and National Hunt (NH) jump racing. 43,417 SNPs were employed to perform a genome-wide association analysis and to estimate the proportion of genetic variance attributable to the SNPs on each chromosome using restricted maximum likelihood (REML). Significant genetic variation associated with fracture risk was found on chromosomes 9, 18, 22 and 31. Three SNPs on chromosome 18 (62.05 Mb – 62.15 Mb) and one SNP on chromosome 1 (14.17 Mb) reached genome-wide significance (p &lt;0.05) in a genome-wide association study (GWAS). Two of the SNPs on ECA 18 were located in a haplotype block containing the gene zinc finger protein 804A (ZNF804A). One haplotype within this block has a protective effect (controls at 1.95 times less risk of fracture than cases, p = 1 × 10-4), while a second haplotype increases fracture risk (cases at 3.39 times higher risk of fracture than controls, p = 0.042). Conclusions: Fracture risk in the Thoroughbred horse is a complex condition with an underlying genetic basis. Multiple genomic regions contribute to susceptibility to fracture risk. This suggests there is the potential to develop SNP-based estimators for genetic risk of fracture in the Thoroughbred racehorse, using methods pioneered in livestock genetics such as genomic selection. This information would be useful to racehorse breeders and owners, enabling them to reduce the risk of injury in their horses

    Girls Excelling in Math and Science (GEMS): Stories of the Original GEMS Girls

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    Girls Excelling in Math and Science (GEMS) is an afterschool club started in 1994 by a parent, Laura Reasoner Jones, who was dismayed to hear her 10-year old daughter Julie opt herself out of attending a magnet school because “Math is hard.” Julie’s math performance had been good in school, therefore Laura wondered what else might be causing her self doubt. Laura decided to address the issue. Collaborating with Julie’s teacher, she started the first GEMS club for Julie and her friends in fifth and sixth grade. During the following 25 years, GEMS clubs have operated globally to provide resources to support leaders to implement community-based, single-sex learning environments with over 200 hands-on STEM activities. Through the website library, GEMS provides free, equal access to these activities for students, parents, and educators. The mission of GEMS is to cultivate curiosity and confidence in STEM for girls in elementary and secondary school

    Navigating uncharted territory: Introducing EBLIP into a department

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    What happens in a department when one introduces EBLIP into the daily workflow? The researcher reflects on the challenges and rewards of the first year as a Collections Assessment Librarian, a newly created position in the library

    The Whole is Greater than the Sum of its Parts: Collection Growth Reports & Informed Decision-Making

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    Collection space is an issue within the library. The assessment librarian examined statistics from various resources that are typically collected in the library, but not normally looked at as a whole. These Collection Growth Reports will help library staff to make evidence-based purchasing and weeding decisions
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