Oxford and the Cross-Examination Tournament

Now the truth is that Englishmen are hard as nails, and quite capable of rigorous activity when necessity demands. Furthermore, the students of English collegiate institutions are not only well-grounded in history and politics, but remarkably fluent (at least the debaters) and flexible. There was no reason, as far as I could see, why a British team should not participate in at least two rounds of an American collegiate tournament, debating our question under our rules. It seemed particularly appropriate, further more, to ask them to participate in a cross examination tournament, where the format would allow a type of give-and-take similar to the heckling and interruptions which occur on the floor of the various union societies. Consequently, in the Spring of 1953, we started the long chain of negotiations which led to Oxford\u27s appearance at the Pitt Sixth Annual Cross-Examination Tournament, December 11-12, 1953

Space-time thermodynamics and subsystem observables in a kinetically constrained model of glassy systems

In a recent article [M. Merolle et al., Proc. Natl. Acad. Sci. USA 102, 10837 (2005)] it was argued that dynamic heterogeneity in $d$-dimensional glass formers is a manifestation of an order-disorder phenomenon in the $d+1$ dimensions of spacetime. By considering a dynamical analogue of the free energy, evidence was found for phase coexistence between active and inactive regions of spacetime, and it was suggested that this phenomenon underlies the glass transition. Here we develop these ideas further by investigating in detail the one-dimensional Fredrickson-Andersen (FA) model in which the active and inactive phases originate in the reducibility of the dynamics. We illustrate the phase coexistence by considering the distributions of mesoscopic spacetime observables. We show how the analogy with phase coexistence can be strengthened by breaking microscopic reversibility in the FA model, leading to a non-equilibrium theory in the directed percolation universality class.Comment: 12 pages, 11 figures, final version with minor change

The Portfolio Pension Plan: An Alternative Model for Retirement Security

This chapter describes a proposed new defined benefit (DB) pension design known as a portfolio pension plan. This design falls within a larger category of so-called ‘shared risk’ pension plans. In the United States, shared risk pension plans address a need created by the limitations of existing retirement plan designs. An alternative to existing designs is needed because DB plans to date have concentrated risk on plan sponsors in a way that makes them financially unsustainable in many, if not most, circumstances. Moreover, existing defined contribution (DC) retirement plans impose risk on employees in a way that is challenging for most individuals to manage. In the past, many employers shared risk with employees by providing both a DB and a DC plan. Nevertheless, this chapter argues that a new model can provide an alternative that better serves employers and employees in the United States

Evidence for a Hard Ionizing Spectrum from a z=6.11 Stellar Population

We present the Magellan/FIRE detection of highly-ionized CIV 1550 and OIII] 1666 in a deep infrared spectrum of the z=6.11 gravitationally lensed low-mass galaxy RXC J2248.7-4431-ID3, which has previously-known Lyman-alpha. No corresponding emission is detected at the expected location of HeII 1640. The upper limit on HeII paired with detection of OIII] and CIV constrains possible ionization scenarios. Production of CIV and OIII] requires ionizing photons of 2.5-3.5 Ryd, but once in that state their multiplet emission is powered by collisional excitation at lower energies (~0.5 Ryd). As a pure recombination line, HeII emission is powered by 4 Ryd ionizing photons. The data therefore require a spectrum with significant power at 3.5 Ryd but a rapid drop toward 4.0 Ryd. This hard spectrum with a steep drop is characteristic of low-metallicity stellar populations, and less consistent with soft AGN excitation, which features more 4 Ryd photons and hence higher HeII flux. The conclusions based on ratios of metal line detections to Helium non-detection are strengthened if the gas metallicity is low. RXJ2248-ID3 adds to the growing handful of reionization-era galaxies with UV emission line ratios distinct from the general z=2-3 population, in a way that suggests hard ionizing spectra that do not necessarily originate in AGN.Comment: 7 pages, 4 figures, 1 table. Accepted for publication to ApJ

Glassy behaviour in an exactly solved spin system with a ferromagnetic transition

We show that applying simple dynamical rules to Baxter's eight-vertex model leads to a system which resembles a glass-forming liquid. There are analogies with liquid, supercooled liquid, glassy and crystalline states. The disordered phases exhibit strong dynamical heterogeneity at low temperatures, which may be described in terms of an emergent mobility field. Their dynamics are well-described by a simple model with trivial thermodynamics, but an emergent kinetic constraint. We show that the (second order) thermodynamic transition to the ordered phase may be interpreted in terms of confinement of the excitations in the mobility field. We also describe the aging of disordered states towards the ordered phase, in terms of simple rate equations.Comment: 11 page

Cross-over behaviour in a communication network

We address the problem of message transfer in a communication network. The network consists of nodes and links, with the nodes lying on a two dimensional lattice. Each node has connections with its nearest neighbours, whereas some special nodes, which are designated as hubs, have connections to all the sites within a certain area of influence. The degree distribution for this network is bimodal in nature and has finite variance. The distribution of travel times between two sites situated at a fixed distance on this lattice shows fat fractal behaviour as a function of hub-density. If extra assortative connections are now introduced between the hubs so that each hub is connected to two or three other hubs, the distribution crosses over to power-law behaviour. Cross-over behaviour is also seen if end-to-end short cuts are introduced between hubs whose areas of influence overlap, but this is much milder in nature. In yet another information transmission process, namely, the spread of infection on the network with assortative connections, we again observed cross-over behaviour of another type, viz. from one power-law to another for the threshold values of disease transmission probability. Our results are relevant for the understanding of the role of network topology in information spread processes.Comment: 12 figure

Status, Testosterone, and Human Intellectual Performance: Stereotype Threat as Status Concern

Results from two experiments suggest that stereotype-threat effects are special cases of a more general process involving the need to maintain or enhance status. We hypothesized that situations capable of confirming a performance stereotype might represent either a threat to status or an opportunity for enhancement of status, depending on the nature of the stereotype. The positive relationship between baseline testosterone and status sensitivity led us to hypothesize that high testosterone levels in males and females would amplify existing performance expectations when gender-based math-performance stereotypes were activated. In Study 1, high-testosterone females performed poorly on a math test when a negative performance stereotype was primed. In Study 2, high-testosterone males excelled on a math test when a positive performance stereotype was primed. The moderating effect of testosterone on performance suggests that a stereotype-relevant situation is capable of conferring either a loss or a gain of status on targets of the stereotype.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Subclinical infection of macaques and baboons with a baboon simarterivirus

Simarteriviruses (Arteriviridae: Simarterivirinae) are commonly found at high titers in the blood of African monkeys but do not cause overt disease in these hosts. In contrast, simarteriviruses cause severe disease in Asian macaques upon accidental or experimental transmission. Here, we sought to better understand the host-dependent drivers of simarterivirus pathogenesis by infecting olive baboons (n = 4) and rhesus monkeys (n = 4) with the simarterivirus Southwest baboon virus 1 (SWBV-1). Surprisingly, none of the animals in our study showed signs of disease following SWBV-1 inoculation. Three animals (two rhesus monkeys and one olive baboon) became infected and sustained high levels of SWBV-1 viremia for the duration of the study. The course of SWBV-1 infection was highly predictable: plasma viremia peaked between 1 × 107 and 1 × 108 vRNA copies/mL at 3–10 days post-inoculation, which was followed by a relative nadir and then establishment of a stable set-point between 1 × 106 and 1 × 107 vRNA copies/mL for the remainder of the study (56 days). We characterized cellular and antibody responses to SWBV-1 infection in these animals, demonstrating that macaques and baboons mount similar responses to SWBV-1 infection, yet these responses are ineffective at clearing SWBV-1 infection. SWBV-1 sequencing revealed the accumulation of non-synonymous mutations in a region of the genome that corresponds to an immunodominant epitope in the simarterivirus major envelope glycoprotein GP5, which likely contribute to viral persistence by enabling escape from host antibodies

Real-time in vivo optogenetic neuromodulation and multielectrode electrophysiologic recording with NeuroRighter

Optogenetic channels have greatly expanded neuroscience’s experimental capabilities, enabling precise genetic targeting and manipulation of neuron subpopulations in awake and behaving animals. However, many barriers to entry remain for this technology – including low-cost and effective hardware for combined optical stimulation and electrophysiologic recording. To address this, we adapted the open-source NeuroRighter multichannel electrophysiology platform for use in awake and behaving rodents in both open and closed-loop stimulation experiments. Here, we present these cost-effective adaptations, including commercially available LED light sources; custom-made optical ferrules; 3D printed ferrule hardware and software to calibrate and standardize output intensity; and modifications to commercially available electrode arrays enabling stimulation proximally and distally to the recording target. We then demonstrate the capabilities and versatility of these adaptations in several open and closed-loop experiments, demonstrate spectrographic methods of analyzing the results, as well as discuss artifacts of stimulation.Emory University. School of Medicine (Emory Neurosciences Initiative seed grant)American Epilepsy SocietyEpilepsy Foundation of America (Predoctoral fellowship)National Science Foundation (U.S.) (NSF GRFP Fellowship 08-593)National Science Foundation (U.S.) (NSF IGERT Fellowship DGE-0333411)National Science Foundation (U.S.) (NSF EFRI #1238097)National Institutes of Health (U.S.) (NIH 1R01NS079757-01)American Society for Engineering Education (SMART Fellowship