45 research outputs found
Juvenile Delinquent and Unruly Proceedings in Ohio: Unconstitutional Adjudications
This article will focus on the constitutional defects of juvenile court adjudications under Ohio juvenile law. The arguments presented, however, are equally applicable in other jurisdictions since every state has some type of legislation granting juvenile court jurisdiction over both criminals and noncriminal misconduct of children
Serum procalcitonin and CRP levels in non-alcoholic fatty liver disease: a case control study
<p>Abstract</p> <p>Background</p> <p>Both C reactive protein (CRP) and procalcitonin (PCT) are well known acute phase reactant proteins. CRP was reported to increase in metabolic syndrome and type-2 diabetes. Similarly altered level of serum PCT was found in chronic liver diseases and cirrhosis. The liver is considered the main source of CRP and a source of PCT, however, the serum PCT and CRP levels in non-alcoholic fatty liver disease (NAFLD) were not compared previously. Therefore we aimed to study the diagnostic and discriminative role of serum PCT and CRP in NAFLD.</p> <p>Methods</p> <p>Fifty NAFLD cases and 50 healthy controls were included to the study. Liver function tests were measured, body mass index was calculated, and insulin resistance was determined by using a homeostasis model assessment (HOMA-IR). Ultrasound evaluation was performed for each subject. Serum CRP was measured with nephalometric method. Serum PCT was measured with Kryptor based system.</p> <p>Results</p> <p>Serum PCT levels were similar in steatohepatitis (n 20) and simple steatosis (n 27) patients, and were not different than the control group (0.06 ± 0.01, 0.04 ± 0.01 versus 0.06 ± 0.01 ng/ml respectively). Serum CRP levels were significantly higher in simple steatosis, and steatohepatitis groups compared to healthy controls (7.5 ± 1.6 and 5.2 ± 2.5 versus 2.9 ± 0.5 mg/dl respectively p < 0.01). CRP could not differentiate steatohepatitis from simple steatosis. Beside, three patients with focal fatty liver disease had normal serum CRP levels.</p> <p>Conclusion</p> <p>Serum PCT was within normal ranges in patients with simple steatosis or steatohepatitis and has no diagnostic value. Serum CRP level was increased in NAFLD compared to controls. CRP can be used as an additional marker for diagnosis of NAFLD but it has no value in discrimination of steatohepatitis from simple steatosis.</p
The route of the catheter directly affects the volume needed in experimental corrosive esophagitis
WOS: 000260184900019PubMed ID: 1881046
Incomplete esophageal duplication presenting with reflux symptoms in an adult
WOS: 000283606200016PubMed ID: 2087233
Giant Esophageal Lipoma Presenting with Gastroesophageal Reflux Symptoms
WOS: 000317531100002PubMed ID: 2353940
The ACE gene I/D polymorphism does not affect the susceptibility to or prognosis of PBC
WOS: 000262761100006PubMed ID: 19119484Background/aims: Primary biliary cirrhosis is an autoimmune liver disease that is strongly influenced by poorly defined, complex genetic factors. Alterations of the renin-angiotensin. system have been implicated in the pathogenesis of various diseases. A deletion polymorphism of a 287-bp fragment of intron 16 of the angiotensin converting enzyme gene allele results in higher levels of circulating enzyme. Angiotensin converting enzyme deletion genotype has been linked to hypertension and sarcoidosis and has been reported to regulate liver fibrosis in HCV-mediated liver disease. We investigated the frequency of the Angiotensin converting enzyme gene insertion/deletion polymorphism in primary biliary cirrhosis patients. Methods: 52 biopsy-proven primary biliary cirrhosis patients and 98 healthy controls were evaluated. Angiotensin converting enzyme insertion/deletion polymorphism was detected by polymerase chain reaction amplification of a genomic DNA fragment on intron 16 of the angiotensin converting enzyme gene. Clinical phenotype of primary biliary cirrhosis was verified with positive anti-mitochondrial antibody or M2 antibody, demonstration of cholestatic liver enzymes, and staging of liver biopsy. The differences between these variables among different genotypes were noted. Results: There was no significant difference in. genotypes and allele frequency between the primary biliary cirrhosis group and controls. The D allele frequency was 54% in primary biliary cirrhosis cases and 55% in controls (p=ns). Furthermore, there was no significant difference in clinical features between patients with angiotensin converting enzyme-insertion, or insertion/deletion genotypes vs. patients with angiotensin converting enzyme-deletion genotype. Conclusions: In our limited sample, the angiotensin converting enzyme deletion genotype did not make a. significant contribution to the pathogenesis or progression of primary biliary cirrhosis
Diagnosis of Campylobacteriosis in the Aborted Bovine Foetuses by Pathological, Immunohistochemical, Microbiological and Real Time PCR
WOS: 000278340800026In this study; 105 aborted bovine fetuses were examined for Campylobacteriosis and pathologic findings were compared with microbiologic, immunohistochemical and real time polimerase chain reaction (Real Time-PCR) methods. Although, Campylobacter spp. was microbiologically detected in only 4 cases, this was detected in 5 cases by immunohistochemical method and by Real Time-PCR in 7 cases. It is concluded that 6.6% (7/105) of abortion cases were caused by Campylobacteriosis and Real Time PCR more sensitive and usefull for the the diagnosis of the disease and immunohistochemical method is as sensitive as microbiologic methods for diagnosis in unsufficient labarotories