Simulasi Sistem Untuk Pengontrolan Lampu Dan Air Conditioner Dengan Menggunakan Logika Fuzzy

Energi listrik merupakan salah satu kebutuhan yang sangat vital bagi masyarakat maka sudah seharusnya dalam pemanfaatan energi listrik tersebut diiringi dengan cara pemakaian yang bijak saja. Tetapi Kenyataannya dimasyarakat penggunaan listrik yang mubazir masih banyak terjadi. Contoh kasus yang bisa kita cermati seperti pemakaian lampu dan Air Conditioner (AC) yang dibiarkan tetap menyala pada ruangan kantor padahal di dalam ruangan tidak ada orang sama sekali. Sehingga hal ini bisa menimbulkan pemborosan pada pemakaian daya listrik tersebut. Umumnya, pengaturan penggunaan lampu dan AC hanya dilakukan secara manual tanpa mempertimbangkan intensitas cahaya, temperatur udara dan banyaknya orang dalam ruangan. Oleh karena itu, perlu suatu sistem yang mampu mengontrol penggunaan lampu dan AC tersebut secara otomatis untuk mendapatkan efesiensi penggunaan listrik. Sistem simulasi pengontrolan ini dirancang dengan prinsip kendali logika fuzzy dengan menggunakan sistem inferensi fuzzy adalah metode tsukamoto. Parameter yang digunakan untuk mengatur pemakaian lampu berdasarkan intensitas cahaya yang ada. Sementara parameter untuk mengatur temperatur AC berdasarkan banyak orang dan temperatur udara. Nilai tegas output yang dihasilkan berupa temperatur AC dan jumlah lampu yang bisa dihidupkan. Sistem pengontrolan dengan logika fuzzy lebih efektif dibandingkan dengan cara konvensional, hal ini dikarenakan sistem pengontrolan dengan logika fuzzy dapat menyesuaikan dengan banyak orang, temperatur udara dan intensitas cahaya yang terjadi di sebuah ruanga

Propagation of sound in a Bose Einstein condensate in an optical lattice

We study the propagation of sound waves in a Bose-Einstein condensate trapped in a one-dimensional optical lattice. We find that the velocity of propagation of sound wavepackets decreases with increasing optical lattice depth, as predicted by the Bogoliubov theory. The strong interplay between nonlinearities and the periodicity of the external potential raise new phenomena which are not present in the uniform case. Shock waves, for instance, can propagate slower than sound waves, due to the negative curvature of the dispersion relation. Moreover, nonlinear corrections to the Bogoliubov theory appear to be important even with very small density perturbations, inducing a saturation on the amplitude of the sound signal

Results from a meta-analysis of immune checkpoint inhibitors in first-line renal cancer patients: does PD-L1 matter?

Background: The aim of this study was to perform a literature-based meta-analysis to assess the efficacy of the novel immune checkpoint inhibitors (ICIs) in first-line metastatic renal cell carcinoma (RCC), focusing on the predictive role of PD-L1 expression. Methods: The primary outcome was overall survival, and secondary outcomes were progression-free survival (PFS) and objective response. We planned a subgroup analysis for overall survival according to PD-L1 status. Results: Five studies were included in the analysis for a total of 4063 cases. Overall survival was greater in PD-L1 positive tumours (HR = 0.49, 95% CI: 0.36\u20130.67; p < 0.001). The pooled analysis of the unselected cases showed a statistically significative improvement in PFS with the use of ICIs (HR = 0.85, 95% CI: 0.72\u20130.99; p = 0.04) and we found a greater PFS benefit (HR = 0.65, 95% CI: 0.57\u20130.74; p < 0.001) in patients with PD-L1 positive tumours. Conclusions: This study supports the efficacy of ICIs and, although a significant clinical benefit has been reported in PD-L1 negative patients, a greater efficacy of ICIs was observed in PD-L1 positive patients. More prospective randomized studies are needed to clarify the role of PDL-1 status in metastatic RCC treated with ICIs

Dipole and Bloch oscillations of cold atoms in a parabolic lattice

The paper studies the dynamics of a Bose-Einstein condensate loaded into a 1D parabolic optical lattice, and excited by a sudden shift of the lattice center. Depending on the magnitude of the initial shift, the condensate undergoes either dipole or Bloch oscillations. The effects of dephasing and of atom-atom interactions on these oscillations are discussed.Comment: 3 pages, to appear in proceeding of LPHYS'05 conference (July 4-8, 2005, Kyoto, Japan

Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease

Starting from nature as original source, new potential agents with pleiotropic activities have been synthesized and evaluated as neuroprotective agents. In this work, novel nature-based hybrids, combining antioxidant motifs with rivastigmine, have been designed and synthesized. The biological results revealed that the new compounds inhibit both AChE and BuChE. In particular, lipoic acid hybrids LA1, LA2, LA3 resulted to be the most potent inhibitors of BuChE showing IC50 values ranging from 340 to 378 nM. Analogously, all the compounds were able to inhibit the self β-amyloid1-42 aggregation. The gallic acid hybrid GA2 as well as the 2-chromonecarboxylic acid hybrids CA1 and CA2 prevented the self-mediated Aβ aggregation with percentages of inhibition ranging from 53% to 59%. Finally, some of them also show potent neuroprotective effects against glutamate-induced cell death and low toxicity in HT22 cells

Uso de PPM® (Plant Preservative Mixture) na desinfestação de sementes de guanandi (Calophyllum brasiliense Cambess.), introduzidas in vitro.

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Uso de antioxidantes no estabelecimento in vitro de segmentos nodais de guanandi (Calophyllum brasiliense Cambess.).

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An Innovative Enhanced Wall to Reduce the Energy Demand in Buildings

Energy saving in buildings is one of most important issues for European countries. Although in the last years many studies have been carried out in order to reach the zero-consumption house the energy rate due to passive solar heating could be further enhanced. This paper proposes a method for increasing the energy rate absorbed by opaque walls by using a two phase loop thermosyphon connecting the internal and the external façade of a prefabricated house wall. The evaporator zone is embedded into the outside facade and the condenser is indoor placed to heat the domestic environment. The thermosyphon has been preliminary designed and implanted into a wall for a prefabricated house in Italy. An original dynamic thermal model of the building equipped with the thermosyphon wall allowed the evolution of the indoor temperature over time and the energy saving rates. The transient behaviour of the building has been simulated during the winter period by using the EnergyPlusTM software. The annual saving on the heating energy is higher than 50% in the case of a low consumption building